scholarly journals A Comparative Study of Two Gel-Based Techniques to Detect the Relationship Between Post-Mortem Interval And Nuclear DNA Degradation In Different Tissues In Albino Rats

2020 ◽  
Vol 66 (1) ◽  
pp. 175-186
Author(s):  
Mohamed Mohamed ◽  
Mahmoud El Sherbeny ◽  
Doaa Farag
2021 ◽  
Vol 48 ◽  
pp. 101809
Author(s):  
Weihao Zhu ◽  
Xiandun Zhai ◽  
Zhe Zheng ◽  
Kai Sun ◽  
Mengzi Yang ◽  
...  

2020 ◽  
Vol 21 (10) ◽  
pp. 3540 ◽  
Author(s):  
Pamela Tozzo ◽  
Salvatore Scrivano ◽  
Matteo Sanavio ◽  
Luciana Caenazzo

The determination of the post-mortal interval (PMI) is an extremely discussed topic in the literature and of deep forensic interest, for which various types of methods have been proposed. The aim of the manuscript is to provide a review of the studies on the post-mortem DNA degradation used for estimating PMI. This review has been performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses and the PRISMA Guidelines. Several analytical techniques have been proposed to analyse the post-mortem DNA degradation in order to use it to estimate the PMI. Studies focused mainly on animal models and on particular tissues. The results have been mixed: while on the one hand literature data in this field have confirmed that in the post-mortem several degradation processes involve nucleic acids, on the other hand some fundamental aspects are still little explored: the influence of ante and post-mortem factors on DNA degradation, the feasibility and applicability of a multiparametric mathematical model that takes into account DNA degradation and the definition of one or more target organs in order to standardize the results on human cases under standard conditions.


Author(s):  
Sarita Sharma ◽  
Jyoti Sarah A. Khater ◽  
Eman Abd ElHakim ◽  
Basma Emad Aboulhoda ◽  
Laila Ahmed Rashed ◽  
...  

1989 ◽  
Vol 29 (3) ◽  
pp. 209-217 ◽  
Author(s):  
M. K. Heatley ◽  
J. Crane

The relationship between the blood alcohol concentration and the urine alcohol concentration was studied in 109 routine coroner's autopsies. Although the average ratio for urine alcohol concentration to blood alcohol concentration lay close to the ratio of 4:3 quoted in the literature, the actual ratios determined were widely scattered around this value. Thus the use of this simple ratio to estimate the blood alcohol concentration from the urine alcohol concentration at post-mortem was unreliable. An equation determined by employing linear regression analysis was similarly unhelpful in enabling one to derive a precise value for the blood alcohol concentration from a given urine alcohol concentration. It was concluded that the main value in determining the urine alcohol concentration at autopsy was to exclude the possibility of the alcohol present in the blood sample having been generated during the post-mortem interval.


Author(s):  
Mona El-Harouny ◽  
Sahar El-Dakroory ◽  
Sohayla Attalla ◽  
Nermin, Hasan ◽  
Sobhy El-Nabi

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