scholarly journals The physiological uptake pattern of 18F-FDG in the left ventricular myocardium of patients without heart disease

2014 ◽  
Vol 61 (1.2) ◽  
pp. 53-58 ◽  
Author(s):  
Hayato Nose ◽  
Hideki Otsuka ◽  
Yoichi Otomi ◽  
Kaori Terazawa ◽  
Shoichiro Takao ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Left Ventricular Myocardium ◽  
Physiological Uptake ◽  
Uptake Pattern ◽  
18F Fdg

scholarly journals Selected clinical parameters and changes in cardiac morphology and function assessed by magnetic resonance imaging in patients with rheumatoid arthritis and ankylosing spondylitis without clinically apparent heart disease

2021 ◽  
Author(s):  
Wojciech Tański ◽  
Paweł Gać ◽  
Angelika Chachaj ◽  
Małgorzata Sobieszczańska ◽  
Rafał Poręba ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Pericardial Fluid ◽  
Independent Effect ◽  
Left Ventricular Myocardium ◽  
Leukocyte Antigen ◽  
Independent Risk Factors ◽  
Occurrence Type

Abstract Background The aim of the study was to assess the relationship between the occurrence of rheumatoid arthritis (RA) and ankylosing spondylitis (AS) and the cardiac magnetic resonance (CMR) changes in people without clinically overt heart disease. Methods The study group consisted of 74 people (48.81 ± 11.35 years): 29 patients with RA, 23 patients with AS and 22 people from control group. Blood samples were taken to assess laboratory parameters, disease activity was determined using activity scales, and CMR was performed. Results It was shown that the factors independently related to higher left ventricular mass index are AS occurrence, human B27 leukocyte antigen occurrence, higher neutrophil gelatinase–associated lipocalin concentration (NGAL) and higher body mass index (BMI). The lower right ventricular ejection fraction is result of an independent effect of RA, AS and higher NGAL. RA presence, methotrexate use, higher rheumatoid factor titer, higher NGAL, older age and higher BMI should be considered independent risk factors for greater left ventricular myocardium water content. RA occurrence, AS occurrence, type 2 diabetes occurrence and a higher C-reactive protein concentration can be independently associated with a higher probability of non-ischemic left ventricular myocardium injury. Larger pericardial fluid volume is result of an independent effect of higher NGAL, higher anti-cyclic citrullinated peptide antibodies titer and higher DAS28 disease activity index. Use of steroids is protective factor against larger volume of pericardial fluid. Conclusions RA and AS in people without clinically apparent heart disease are associated with the occurrence of adverse changes in CMR. Key Points•RA and AS in people without clinically apparent heart disease are associated with the occurrence of adverse changes in CMR..•The independent risk factors for higher LVEF are AS occurrence, human B27 leukocyte antigen occurrence, higher NGAL concentration and higher BMI..•RA presence, methotrexate use, higher RF, higher NGAL, older age and higher BMI are independent risk factors for higher LV T2 ratio..•RA occurrence, AS occurrence, type 2 diabetes occurrence and a higher CRP are independently associated with a higher risk of non-ischemic LV myocardium injury..

Quality of Life of Patients With Ischemic Heart Disease and Pronounced Dysfunction of Left Ventricular Myocardium With Medical and Surgical Treatments

Kardiologiia ◽  
2015 ◽  
Vol 4_2015 ◽  
pp. 5-13
Author(s):  
A.M. Chernyavsky Chernyavsky ◽  
O.S. Efanova Efanova ◽  
V.U. Efendiyev Efendiyev ◽  
D.A. Sirota Sirota ◽  
E.M. Alyapkina Alyapkina ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Left Ventricular Myocardium ◽  
Surgical Treatments

scholarly journals Cardiac Tuberculosis on 18F-FDG PET Imaging—A Great Masquerader of Cardiac Sarcoidosis

2021 ◽  
Author(s):  
Sumati Sundaraiya ◽  
Abubacker Sulaiman ◽  
Adhithyan Rajendran
Keyword(s):  
Pet Imaging ◽  
Fdg Pet ◽  
Cardiac Sarcoidosis ◽  
Granulomatous Inflammation ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Whole Body ◽  
Left Ventricular Myocardium ◽  
Fdg Uptake ◽  
18F Fdg

AbstractA young gentleman with suspected cardiac sarcoidosis and LV dysfunction whose CMR revealed multifocal subepicardial to mid myocardial linear enhancement in the left ventricular myocardium underwent cardiac 18F-FDG PET imaging. The images revealed patchy regions of increased FDG uptake involving the apical to mid anterolateral, mid to basal anteroseptal/ right ventricular and mildly increased FDG uptake in apical inferior segments of the LV myocardium concordant with CMR findings. Whole body PET CT imaging showed multiple hypermetabolic supra and infra diaphragmatic lymphadenopathy, with no pulmonary lesion identified. Biopsy from the left para aortic lymph node revealed necrotizing granulomatous inflammation consistent with tuberculosis. Based on the histopathological findings of the lymph nodes, diagnosis of cardiac tuberculosis was made, given the similar imaging appearances in both sarcoidosis and TB. This case highlights that cardiac TB although rare, should be included in the differential diagnosis in patients with suspected infiltrative cardiomyopathy, particularly in TB endemic regions.

Dynamics of Structural – Functional State of the Left Ventricle in Patients with Hypertension and Chronic Ischemic Heart Disease on the Background of Gastroesophageal Reflux Disease Under the Influence of Antihypertensive and Antireflux Therapy

2016 ◽  
pp. 102-107
Author(s):  
Diana Moreva
Keyword(s):  
Heart Disease ◽  
Left Ventricle ◽  
Ischemic Heart Disease ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Ischemic Heart ◽  
Left Ventricular Myocardium ◽  
Chronic Ischemic Heart Disease ◽  
Concentric Hypertrophy ◽  
Antireflux Therapy

Diseases of the circulatory system are the most common pathology in Ukraine and cover 26,2 mln. Population 12,3 mln ukrainians suffer from hypertension (AH). Gastroesophageal reflux disease (GERD) is recognized by the World Organization of Gastroenterology disease of the XXI century. Given the common risk factors for hypertension coronary heart disease (CHD) and the question of GERD studies of the combined flow of these diseases and to optimize the treatment of these patients. The objective: to determine the characteristics of intracardiac hemodynamics in patients with hypertension combined with chronic ischemic heart disease on the background of GERD and the determination of the combined effects of antihypertensive and antireflux therapy on the structural-functional state of the left ventricular myocardium. Patients and methods. We examined 107 patients aged 44 to 78 years, with an established diagnosis of hypertension stage I and II in combination with chronic ischemic heart disease. Research methods included anthropometric studies, biochemical blood analysis, ambulatory blood pressure monitoring, the daily ECG monitoring, esophagogas-troduodenoscopy (EGD), echocardiography (echocardiography), testing. Results. Comorbidity for hypertension, chronic ischemic heart disease and GERD is associated with a higher frequency of abdominal type of obesity and the metabolic syndrome according to IDF criteria, significantly higher percentage of patients with grade II and III obesity. That in turn is reflected in the features of the structural1functional state of the left ventricle (LV), which manifests an increase in the number of patients with more severe degrees of left ventricular hypertrophy. Related GERD is associated with a large percentage of cases of concentric hypertrophy of the left ventricle, and a greater prevalence of diastolic dysfunction. The combination of antihypertensive and antireflux therapy for 12 weeks of treatment was reflected in the significant decrease in the weight of the index parameters of left ventricular myocardium (LVMI) and relative wall thickness index and reliable positive dynamics of indicators of left ventricular diastolic function. Conclusion. Patients with hypertension combined with chronic ischemic heart disease with comorbidity with GERD have a higher prevalence of factors of cardiovascular risk. Related GERD is associated with a more severe degree of left ventricular hypertrophy, with a large percentage of cases of concentric hypertrophy of the left ventricle, and a greater prevalence of diastolic dysfunction. A combination of antihypertensive and antireflux therapy for 12 weeks of treatment promoted significant reduction in myocardial mass index indicators LV (LVMI) and relative wall thickness index and had a significant impact on the normalization of LV diastolic function.

scholarly journals The use of methods of spatial displacement of the myocardial structure (speckle tracking) to determine the indications for coronary angiography in patients suffering from coronary heart disease

2020 ◽  
Vol 22 (2) ◽  
pp. 70-73
Author(s):  
A. N. Kuchmin ◽  
M. Y. Yaroslavtcev ◽  
N. V. Afendikov ◽  
E. P. Galova ◽  
K. B. Evsukov ◽  
...  
Keyword(s):  
Coronary Heart Disease ◽  
Heart Disease ◽  
Coronary Angiography ◽  
Speckle Tracking ◽  
Ventricular Myocardium ◽  
Left Ventricular ◽  
Left Ventricular Myocardium ◽  
Longitudinal Deformation ◽  
Spatial Displacement ◽  
Myocardial Structure

The indicators of global and segmental longitudinal deformation of the left ventricular myocardium are presented and analyzed in patients suffering from coronary heart disease. The latter, as before, remains one of the urgent diseases of the circulatory system. To verify and determine management tactics for patients suffering from coronary heart disease, coronary angiography is performed. Indications for its implementation are based on the results of exercise tests, in particular, stress echocardiography. However, its implementation can be difficult due to poor visualization of the walls of the left ventricle, and the conclusion is not without subjectivity. One of the modern methods for assessing the contractility of the left ventricular myocardium, both global and segmental, is the spatial displacement of the myocardial structure (speckle-tracking- echocardiography). The technique automatically calculates the longitudinal deformation of the myocardium, expressed as a percentage of the initial values. It was found that the global and segmental longitudinal deformation of the left ventricular myocardium in the majority of the evaluated segments in the examined patients did not differ before loading. When conducting a stress test, the exact opposite dynamics of changes in the parameters of the global and segmental longitudinal deformation of the left ventricular myocardium is observed. So, in patients with a high risk of complications of coronary heart disease, a decrease in these indicators was observed, in patients without a risk of complications, on the contrary, their increase was observed, which indicates an increase in myocardial contractility during physical exertion. It was revealed that the indicator of global longitudinal deformation of the left ventricular myocardium is highly informative. The lower value of the decrease in the global longitudinal deformation of the left ventricular myocardium was calculated, which can serve as an additional indication for coronary angiography.

scholarly journals The physiological uptake pattern of 18F-FDG in the left ventricular myocardium of patients without heart disease

2000 ◽  
Vol 40 (1.2) ◽  
pp. 53-58
Author(s):  
Hayato Nose ◽  
Hideki Otsuka ◽  
Yoichi Otomi ◽  
Kaori Terazawa ◽  
Shoichiro Takao ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ventricular Myocardium ◽  
Physiological Uptake ◽  
Uptake Pattern
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