scholarly journals The use of methods of spatial displacement of the myocardial structure (speckle tracking) to determine the indications for coronary angiography in patients suffering from coronary heart disease

2020 ◽  
Vol 22 (2) ◽  
pp. 70-73
Author(s):  
A. N. Kuchmin ◽  
M. Y. Yaroslavtcev ◽  
N. V. Afendikov ◽  
E. P. Galova ◽  
K. B. Evsukov ◽  
...  

The indicators of global and segmental longitudinal deformation of the left ventricular myocardium are presented and analyzed in patients suffering from coronary heart disease. The latter, as before, remains one of the urgent diseases of the circulatory system. To verify and determine management tactics for patients suffering from coronary heart disease, coronary angiography is performed. Indications for its implementation are based on the results of exercise tests, in particular, stress echocardiography. However, its implementation can be difficult due to poor visualization of the walls of the left ventricle, and the conclusion is not without subjectivity. One of the modern methods for assessing the contractility of the left ventricular myocardium, both global and segmental, is the spatial displacement of the myocardial structure (speckle-tracking- echocardiography). The technique automatically calculates the longitudinal deformation of the myocardium, expressed as a percentage of the initial values. It was found that the global and segmental longitudinal deformation of the left ventricular myocardium in the majority of the evaluated segments in the examined patients did not differ before loading. When conducting a stress test, the exact opposite dynamics of changes in the parameters of the global and segmental longitudinal deformation of the left ventricular myocardium is observed. So, in patients with a high risk of complications of coronary heart disease, a decrease in these indicators was observed, in patients without a risk of complications, on the contrary, their increase was observed, which indicates an increase in myocardial contractility during physical exertion. It was revealed that the indicator of global longitudinal deformation of the left ventricular myocardium is highly informative. The lower value of the decrease in the global longitudinal deformation of the left ventricular myocardium was calculated, which can serve as an additional indication for coronary angiography.

2018 ◽  
Vol 20 (1) ◽  
pp. 117-120
Author(s):  
A N Kuchmin ◽  
E P Galova ◽  
D A Galaktionov ◽  
A A Kazachenko ◽  
M Yu Yaroslavtsev ◽  
...  

Topical issues of evaluation, as well as practical application of longitudinal deformities of left ventricular myocardium in the diagnosis of cardiovascular diseases are considered. A study was conducted with an estimation of the segmented reference values for longitudinal deformation of the left ventricular myocardium in healthy middle-aged people using the technique of speckle tracking echocardiography. The essence of the methodic is to track coded areas of the myocardium (speckles) in the gray-scale image with subsequent automatic processing of data by special software. The data obtained are presented in the form of graphs and polar diagrams. This methodic has advantages over the method of tissue dopplerography, because it is more objective, sensitive and requires less time for data processing and analysis. At the same time speckle tracking has a number of limitations. To assess deformation, a good visualization of the image and a regular rhythm are required, and, most importantly, there are no generally accepted standards, since each manufacturer of echocardiographic equipment applies various filters that counteract the scattering of an ultrasonic beam. The effect of these filters on the results is unknown and, therefore, it is impossible to compare the data obtained on different devices. In addition, in the present work, correlation links between the structural and functional state of the myocardium and indices of longitudinal deformation of segments of the left ventricle are revealed. These results reveal the physiological features of the process in myocardial contractility occurring in the heart, both in norm and pathology.


10.12737/7364 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 0-0
Author(s):  
Малыгина ◽  
V. Malygina ◽  
Сергунина ◽  
I. Sergunina ◽  
Туаева ◽  
...  

Currently, the methods of early diagnosis and treatment of stable angina are of interest to researchers. One of the methods of diagnosis is echocardiography using a two-dimensional speckle tracking. Technology speckle tracking allows to evaluate systolic and diastolic heart function in various cardiovascular diseases, including coronary heart disease (CHD). By means of this program all types of myocardial deformation: radial, circular, longitudinal, the rate of deformation and rotation of the myocardium can be evaluated. The clinical studies have shown that changes in the indices of deformation are sensitive markers of myocardial ischemia in the early stages [9]. In this study the authors investigated the effect of anti-anginal drug Coronater on the parameters of radial, circular and longitudinal deformation of the left ventricular myocardium in patients with angina pectoris 1-2 functional class (FC). The drug Coronater is phytotherapeutic preparation of anti-anginal action used to treat angina FC 1-2. The main active ingredients are Ligustikum Sichuan and broneol. Most clinical studies confirm the effectiveness of anti-anginal drug Coronater having significant coronarolytic and anti-ischemic effects.


2021 ◽  
Vol 25 (4) ◽  
pp. 589-592
Author(s):  
V. Yu. Maslovsky

Annotation. In Ukraine, one of the most pressing medical and social problems is coronary heart disease, in particular, such a form as myocardial infarction. Also, as in most countries, coronary heart disease plays a leading role in morbidity and mortality. In Ukraine, coronary heart disease accounts for 65% of the mortality from diseases of the circulatory system of the working population and is the main cause of disability. The aim of the work is to determine the features of the structural and functional state of the myocardium in patients with myocardial infarction without ST segment elevation depending on the nature of the anatomical lesion of the coronary arteries. We conducted a comprehensive study of 200 patients with acute myocardial infarction without ST-segment elevation (NSTEMI) aged 38 to 80 years. According to coronary angiography, the degree of damage to the coronary arteries was determined, and according to echocardiography – the structural and functional state of the myocardium. Comparison of percentages between groups was performed by the criterion χ2, absolute values – by Mann-Whitney U test. The structural condition of the left ventricular myocardium in NSTEMI patients deteriorated significantly. The total severity of coronary artery disease, calculated from coronary angiography, was> 3, indicating a more severe anatomical lesion of the coronary arteries in these patients. This pathology was associated primarily with an increase in the incidence of eccentric left ventricular hypertrophy. A similar association has been established with regard to the development of left ventricular diastolic dysfunction.


Author(s):  
Wojciech Tański ◽  
Paweł Gać ◽  
Angelika Chachaj ◽  
Małgorzata Sobieszczańska ◽  
Rafał Poręba ◽  
...  

Abstract Background The aim of the study was to assess the relationship between the occurrence of rheumatoid arthritis (RA) and ankylosing spondylitis (AS) and the cardiac magnetic resonance (CMR) changes in people without clinically overt heart disease. Methods The study group consisted of 74 people (48.81 ± 11.35 years): 29 patients with RA, 23 patients with AS and 22 people from control group. Blood samples were taken to assess laboratory parameters, disease activity was determined using activity scales, and CMR was performed. Results It was shown that the factors independently related to higher left ventricular mass index are AS occurrence, human B27 leukocyte antigen occurrence, higher neutrophil gelatinase–associated lipocalin concentration (NGAL) and higher body mass index (BMI). The lower right ventricular ejection fraction is result of an independent effect of RA, AS and higher NGAL. RA presence, methotrexate use, higher rheumatoid factor titer, higher NGAL, older age and higher BMI should be considered independent risk factors for greater left ventricular myocardium water content. RA occurrence, AS occurrence, type 2 diabetes occurrence and a higher C-reactive protein concentration can be independently associated with a higher probability of non-ischemic left ventricular myocardium injury. Larger pericardial fluid volume is result of an independent effect of higher NGAL, higher anti-cyclic citrullinated peptide antibodies titer and higher DAS28 disease activity index. Use of steroids is protective factor against larger volume of pericardial fluid. Conclusions RA and AS in people without clinically apparent heart disease are associated with the occurrence of adverse changes in CMR. Key Points•RA and AS in people without clinically apparent heart disease are associated with the occurrence of adverse changes in CMR..•The independent risk factors for higher LVEF are AS occurrence, human B27 leukocyte antigen occurrence, higher NGAL concentration and higher BMI..•RA presence, methotrexate use, higher RF, higher NGAL, older age and higher BMI are independent risk factors for higher LV T2 ratio..•RA occurrence, AS occurrence, type 2 diabetes occurrence and a higher CRP are independently associated with a higher risk of non-ischemic LV myocardium injury..


Kardiologiia ◽  
2015 ◽  
Vol 4_2015 ◽  
pp. 5-13
Author(s):  
A.M. Chernyavsky Chernyavsky ◽  
O.S. Efanova Efanova ◽  
V.U. Efendiyev Efendiyev ◽  
D.A. Sirota Sirota ◽  
E.M. Alyapkina Alyapkina ◽  
...  

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