scholarly journals Abnormal regional spontaneous neural activity in visual pathway in retinal detachment patients: a resting-state functional MRI study

2017 ◽  
Vol Volume 13 ◽  
pp. 2849-2854 ◽  
Author(s):  
Xin Huang ◽  
Dan Li ◽  
Hai-Jun Li ◽  
Yu-Lin Zhong ◽  
Shelby Freeberg ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Functional Mri ◽  
Neural Activity ◽  
Resting State ◽  
Visual Pathway ◽  
Spontaneous Neural Activity ◽  
Mri Study

scholarly journals Disrupted Spontaneous Neural Activity in Patients With Thyroid-Associated Ophthalmopathy: A Resting-State fMRI Study Using Amplitude of Low-Frequency Fluctuation

2021 ◽  
Vol 15 ◽  
Author(s):  
Wen Chen ◽  
Qian Wu ◽  
Lu Chen ◽  
Jiang Zhou ◽  
Huan-Huan Chen ◽  
...  
Keyword(s):  
Neural Activity ◽  
Resting State ◽  
Low Frequency ◽  
Occipital Lobe ◽  
Frequency Fluctuation ◽  
Clinical Activity ◽  
Spontaneous Neural Activity ◽  
Thyroid Associated Ophthalmopathy ◽  
Middle Occipital Gyrus ◽  
Left Middle

PurposeThe purpose of the study was to investigate the brain functional alteration in patients with thyroid-associated ophthalmopathy (TAO) by evaluating the spontaneous neural activity changes using resting-state functional magnetic resonance imaging (rs-fMRI) with the amplitude of low-frequency fluctuation (ALFF) method.Materials and MethodsThe rs-fMRI data of 30 TAO patients (15 active and 15 inactive) and 15 healthy controls (HCs) were included for analyses. The ALFF values were calculated and compared among groups. Correlations between ALFF values and clinical metrics were assessed.ResultsCompared with HCs, active TAOs showed significantly decreased ALFF values in the left middle occipital gyrus, superior occipital gyrus, and cuneus. Compared with inactive TAOs, active TAOs showed significantly increased ALFF values in the bilateral precuneus. Additionally, inactive TAOs showed significantly decreased ALFF values in the left middle occipital gyrus, superior occipital gyrus, cuneus, and bilateral precuneus than HCs. The ALFF value in the right precuneus of TAOs was positively correlated with clinical activity score (r = 0.583, P < 0.001) and Mini-Mental State Examination (MMSE) score (r = 0.377, P = 0.040), and negatively correlated with disease duration (r = −0.382, P = 0.037). Moreover, the ALFF value in the left middle occipital gyrus of TAOs was positively correlated with visual acuity (r = 0.441, P = 0.015).ConclusionTAO patients had altered spontaneous brain activities in the left occipital lobe and bilateral precuneus. The neuropsychological aspect of the disease should be noticed during clinical diagnosis and treatment.

scholarly journals Altered Spontaneous Brain Activity in Patients with Hemifacial Spasm: A Resting-State Functional MRI Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (1) ◽  
pp. e0116849 ◽  
Author(s):  
Ye Tu ◽  
Yongxu Wei ◽  
Kun Sun ◽  
Weiguo Zhao ◽  
Buwei Yu
Keyword(s):  
Functional Mri ◽  
Hemifacial Spasm ◽  
Resting State ◽  
Brain Activity ◽  
Spontaneous Brain Activity ◽  
Mri Study

Liver transplantation nearly normalizes brain spontaneous activity and cognitive function at 1 month: a resting-state functional MRI study

2015 ◽  
Vol 30 (4) ◽  
pp. 979-988 ◽  
Author(s):  
Yue Cheng ◽  
Lixiang Huang ◽  
Xiaodong Zhang ◽  
Jianhui Zhong ◽  
Qian Ji ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Cognitive Function ◽  
Spontaneous Activity ◽  
Functional Mri ◽  
Resting State ◽  
Mri Study
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