scholarly journals Altered amplitude of low-frequency fluctuation and regional cerebral blood flow in females with primary dysmenorrhea: a resting-state fMRI and arterial spin labeling study

2019 ◽  
Vol Volume 12 ◽  
pp. 1243-1250 ◽  
Author(s):  
Ya-Nan Zhang ◽  
Jian-Wei Huo ◽  
Yi-Ran Huang ◽  
Ying Hao ◽  
Zi-Yue Chen
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Resting State ◽  
Arterial Spin Labeling ◽  
Regional Cerebral Blood Flow ◽  
Low Frequency ◽  
Resting State Fmri ◽  
Spin Labeling ◽  
Primary Dysmenorrhea ◽  
Regional Cerebral Blood

Aberrant resting-state cerebral blood flow and its connectivity in primary dysmenorrhea on arterial spin labeling MRI

2020 ◽  
Vol 73 ◽  
pp. 84-90 ◽  
Author(s):  
Ya-Nan Zhang ◽  
Yi-Ran Huang ◽  
Jun-Lian Liu ◽  
Feng-Quan Zhang ◽  
Bing-Yue Zhang ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Resting State ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Primary Dysmenorrhea

scholarly journals Quantitative Changes in Regional Cerebral Blood Flow Induced by Cold, Heat and Ischemic Pain

2012 ◽  
Vol 117 (4) ◽  
pp. 857-867 ◽  
Author(s):  
Michael A. Frölich ◽  
Hrishikesh Deshpande ◽  
Timothy Ness ◽  
Georg Deutsch
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Arterial Spin Labeling ◽  
Regional Cerebral Blood Flow ◽  
Spin Labeling ◽  
Angular Gyrus ◽  
Ischemic Pain ◽  
Regional Cerebral Blood ◽  
Cold Pain ◽  
Area 6

Background The development of arterial spin labeling methods has allowed measuring regional cerebral blood flow (rCBF) quantitatively and to show the pattern of cerebral activity associated with any state such as a sustained pain state or changes due to a neurotropic drug. Methods The authors studied the differential effects of three pain conditions in 10 healthy subjects on a 3 Tesla scanner during resting baseline, heat, cold, and ischemic pain using continuous arterial spin labeling. Results Cold pain showed the greatest absolute rCBF increases in left anterior cingulate cortex, left amygdala, left angular gyrus, and Brodmann area 6, and a significant rCBF decrease in the cerebellum. Changes in rCBF were characteristic of the type of pain condition: cold and heat pain showed increases, whereas the ischemic condition showed a reduction in mean absolute gray matter flow compared with rest. An association of subjects' pain tolerance and cerebral blood flow was noted. Conclusions The observation that quantitative rCBF changes are characteristic of the pain task used and that there is a consistent rCBF change in Brodman area 6, an area responsible for the integration of a motor response to pain, should provide extremely useful information in the quest to develop an imaging biomarker of pain. Conceivably, response in BA6 may serve as an objective measure of analgesic efficacy.

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