scholarly journals Ginger Extract Increases GLUT-4 Expression Preferentially Through AMPK Than PI3K Signalling Pathways in C2C12 Muscle Cells

2020 ◽  
Vol Volume 13 ◽  
pp. 3231-3238
Author(s):  
Marjan Tajik Kord ◽  
Fatemeh Pourrajab ◽  
Seyedhossein Hekmatimoghaddam
1991 ◽  
Vol 266 (4) ◽  
pp. 2615-2621 ◽  
Author(s):  
U M Koivisto ◽  
H Martinez-Valdez ◽  
P J Bilan ◽  
E Burdett ◽  
T Ramlal ◽  
...  

2007 ◽  
Vol 582 (1) ◽  
pp. 41-61 ◽  
Author(s):  
Takashi Sakamoto ◽  
Toshihiro Unno ◽  
Takio Kitazawa ◽  
Tetsuro Taneike ◽  
Masahisa Yamada ◽  
...  

Aging Cell ◽  
2018 ◽  
pp. e12844 ◽  
Author(s):  
Bethan A. Brown ◽  
Georgia M. Connolly ◽  
Carina E. J. Mill ◽  
Helen Williams ◽  
Gianni D. Angelini ◽  
...  

Brain ◽  
2000 ◽  
Vol 123 (2) ◽  
pp. 374-379 ◽  
Author(s):  
P. Baron ◽  
D. Galimberti ◽  
L. Meda ◽  
E. Prat ◽  
E. Scarpini ◽  
...  

2008 ◽  
Vol 32 (4) ◽  
pp. 364
Author(s):  
Leonard Tedong ◽  
Louis C. Martineau ◽  
Ali Benhaddou-Andaloussi ◽  
Hoda M. Eid ◽  
Pierre S. Haddad

2002 ◽  
Vol 34 (6) ◽  
pp. A68
Author(s):  
Sabina Vogel ◽  
Thomas Kubin ◽  
Elisabeth Deindl ◽  
Matthias Heil ◽  
Wolfgang Schaper ◽  
...  

2019 ◽  
Vol 32 (4) ◽  
pp. 210-218
Author(s):  
Tetiana Halenova ◽  
Natalia Raksha ◽  
Olha Kravchenko ◽  
Tetiana Vovk ◽  
Alona Yurchenko ◽  
...  

Abstract The aim of the present study was to evaluate the hypoglycemic activity of the aqueous extract from the fruit walls of Phaseolus vulgaris pods and to examine the potential mechanism underlying the improvement of the glycemic level. In the course of the study, diabetes mellitus was induced in rats with a single intraperitoneal injection of streptozotocin (45 mg·kg−1 b.w.). Diabetic and control rats were then orally administered with a single-dose or repeated-dose (28 day) of P. vulgaris extract (200 mg·kg−1). Results show that the extract was found to possess significant hypoglycemic activity, and the study of glucose utilization by isolated rat hemidiaphragm suggests that the aqueous extract may enhance the peripheral utilization of glucose. The subsequent experiments have revealed that the P. vulgaris extract could increase glucose transporter 4 (GLUT-4) content in skeletal muscle cells of control and diabetic rats. Our data also indicate that the P. vulgaris extract did not affect the content of the insulin receptor, but significantly reduced the total tyrosine kinase activity in skeletal muscle cells of both experimental groups of rats. The present results clearly indicated that P. vulgaris extract may be beneficial for reducing hyperglycemia through its potency in regulation of glucose utilization via GLUT-4, but the current mechanism remains to be unidentified.


Life Sciences ◽  
2016 ◽  
Vol 151 ◽  
pp. 167-173 ◽  
Author(s):  
Fatma Hadrich ◽  
Marie Garcia ◽  
Amina Maalej ◽  
Marthe Moldes ◽  
Hiroko Isoda ◽  
...  

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