scholarly journals Design and physicochemical characterization of advanced spray-dried tacrolimus multifunctional particles for inhalation

2013 ◽  
pp. 59 ◽  
Author(s):  
Heidi Mansour ◽  
Wu ◽  
Don Hayes ◽  
Zwischenberger ◽  
Robert Kuhn
2016 ◽  
Vol Volume 10 ◽  
pp. 4017-4030 ◽  
Author(s):  
Hyo-Jung Lee ◽  
Ji-Hyun Kang ◽  
Hong-Goo Lee ◽  
Dong-Wook Kim ◽  
Yun-Seok Rhee ◽  
...  

1984 ◽  
Vol 73 (2) ◽  
pp. 173-179 ◽  
Author(s):  
Yoshihisa Matsuda ◽  
Sachiyo Kawaguchi ◽  
Hitomi Kobayashi ◽  
Jujiro Nishijo

Author(s):  
Cassandra Meireles Terres-Ribeiro ◽  
André Marcelo Knak ◽  
Rosana Aparecida da Silva Buzanello ◽  
Denise Pastore de Lima ◽  
Roberto Montanhini Neto ◽  
...  

Abstract: The objective of this work was to enzymatically obtain hydrolysate tilapia protein powder by two drying methods, and to perform a physicochemical characterization of the final products, as well as to evaluate their thermal stability. Proximal composition, aminogram, fatty acid profile, pH, color, water activity, and microbiological analyses were performed. Crude protein was the prominent component, with 87% in the spray-dried powder and 89% in the lyophilized powder, showing no statistical difference. The samples showed no bacterial growth, which may be associated with the low water activity in the products. Dry samples had b* positive, and the freeze-dried ones were more yellowish than the spray-dried ones. Both drying methods promoted similar luminosity near the white color. In the thermal analysis, samples showed 26% mass loss at 200°C, and degradation started at 290°C. Enzymatic hydrolysis is efficient, and the hydrolysate tilapia protein powder contains all essential amino acids. The hydrolysate shows similar protein content for both spray-dried and freeze-dried samples, and the final products are stable at high temperatures.


2012 ◽  
Vol 76 (3-4) ◽  
pp. 391-401 ◽  
Author(s):  
Manali Shah ◽  
Yogesh Pore ◽  
Shashikant Dhawale ◽  
Kishorkumar Burade ◽  
Bhanudas Kuchekar

2019 ◽  
Vol 38 (2) ◽  
pp. 385 ◽  
Author(s):  
Marwa M. El-Naggar ◽  
Wael S. I. Abou-Elmagd ◽  
Ashraf Suloma ◽  
Hamza A. El-Shabaka ◽  
Magdy T. Khalil ◽  
...  

Author(s):  
Kumar P ◽  
S Kumar ◽  
A Kumar ◽  
M Chander

The purpose of this study was to prepare and characterize solid dispersions of the antibacterial agent Cefdinir with PEG 4000 and PVP K-30 with a view to improve its dissolution properties. Investigations of the properties of the dispersions were performed using release studies, X-ray powder diffraction (XRD) and Fourier transform infrared (FTIR). The results obtained showed that the rate of dissolution of Cefdinir was considerably improved when formulated in solid dispersions with PVP K-30 and PEG 4000 as compared with pure drug and physical mixtures. The results from XRD studies showed the transition of crystalline nature of drug to amorphous form, while FTIR studies demonstrated the absence of drug-carriers interaction.


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