scholarly journals Familial association of lung cancer with liver cancer in first-degree relatives

2019 ◽  
Vol Volume 11 ◽  
pp. 5813-5819 ◽  
Author(s):  
Chong-Rui Xu ◽  
Huan Lin ◽  
Jian Su ◽  
Xu-Chao Zhang ◽  
Yi-Sheng Huang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Liver Cancer ◽  
First Degree Relatives ◽  
Familial Association

Familial association of lung cancer patients with liver cancer in first-degree relatives.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e13597-e13597
Author(s):  
Chongrui Xu ◽  
Huan Lin ◽  
Xuchao Zhang ◽  
Xuening Yang ◽  
Qing Zhou ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Liver Cancer ◽  
Cancer Patients ◽  
Lung Cancer Patients ◽  
First Degree Relatives ◽  
Familial Association

scholarly journals The association of POLR2E rs3787016 polymorphism and cancer risk: a Chinese case–control study and meta-analysis

2018 ◽  
Vol 38 (6) ◽  
Author(s):  
Bifeng Chen ◽  
Shang Wang ◽  
Guangxin Ma ◽  
Jin Han ◽  
Jingli Zhang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lung Cancer ◽  
Liver Cancer ◽  
Cancer Risk ◽  
Cancer Patients ◽  
Case Control Study ◽  
Meta Analysis ◽  
Case Control ◽  
A Genome ◽  
Control Study

How single nucleotide polymorphisms in long non-coding RNAs are involved in cancer susceptibility remains poorly understood. We hypothesized that polymerase II polypeptide E (POLR2E) rs3787016 polymorphism, identified in a genome-wide association study of prostate cancer, might be a common genetic risk factor for cancer risk. To address this issue, we here conducted a case–control study to investigate the association of POLR2E rs3787016 polymorphism with risk of liver and lung cancer (including 800 normal controls, 480 liver cancer patients, and 550 lung cancer patients), followed by a meta-analysis. The genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism and confirmed by sequencing. Although no significant association was found for rs3787016 with risk of liver or lung cancer, the further stratified analysis identified that rs3787016 contributed to liver cancer risk particularly for over than 60 years individuals who drink. Moreover, the meta-analysis demonstrated that rs3787016 was associated with overall cancer risk and prostate cancer risk. Collectively, the POLR2E rs3787016 polymorphism may be a valuable biomarker for cancer predisposition.

scholarly journals Autopsy Cases of Lung Cancer and Liver Cancer among Japanese Dentists—A Review of the Annual of the Pathological Autopsy Cases in Japan

2011 ◽  
Vol 49 (5) ◽  
pp. 663-671
Author(s):  
Nobuhiro NISHIO ◽  
Hideo TANAKA ◽  
Junko NISHIO ◽  
Katsuyasu KOUDA ◽  
Tatsuya TAKESHITA
Keyword(s):  
Lung Cancer ◽  
Liver Cancer

The Multifactorial Model of Disease Transmission: III. Familial Relationship Between Sociopathy and Hysteria (Briquet's Syndrome)

1975 ◽  
Vol 127 (1) ◽  
pp. 23-32 ◽  
Author(s):  
C. Robert Cloninger ◽  
Theodore Reich ◽  
Samuel B. Guze
Keyword(s):  
General Population ◽  
Assortative Mating ◽  
Disease Transmission ◽  
Family Data ◽  
Multifactorial Model ◽  
First Degree Relatives ◽  
Familial Association ◽  
Familial Relationship ◽  
The Individual ◽  
Clinical Pictures

SummaryHysteria (Briquet's Syndrome) and sociopathy cluster in the same families instead of segregating as independent traits. Assortative mating between hysterics and sociopaths increases the observed similarity between relatives, but the familial association between sociopathy and hysteria remains after taking assortative mating into account. The Multifactorial Model of Disease Transmission with three thresholds related to severity and sex accounts for population and family data about sociopathic men, sociopathic women, and women with hysteria. The data were obtained for 227 first-degree relatives and for 800 subjects in the general population.Depending on the sex of the individual and its severity, the same aetiological process may lead to different, sometimes overlapping, clinical pictures. Specifically, analysis indicates that hysteria in women is a more prevalent and less deviant manifestation of the same process that causes sociopathy in women.

Implementing quality indicators using health insurance claims data linked to the hospital-based cancer registry.

2013 ◽  
Vol 31 (31_suppl) ◽  
pp. 94-94
Author(s):  
Fumiaki Nakamura ◽  
Masato Masuda ◽  
Norihiro Teramoto ◽  
Kazuhiro Mizumoto ◽  
Eiji Mekata ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Colorectal Cancer ◽  
Lung Cancer ◽  
Health Insurance ◽  
Liver Cancer ◽  
Claims Data ◽  
Insurance Claims ◽  
Insurance Claims Data ◽  
Health Insurance Claims Data ◽  
Health Insurance Claims

94 Background: To establish systematic monitoring of cancer care quality, we measured the quality of cancer care in several facilities through chart reviews by tumor registrars. However, this method required both extensive effort of and skills in registrars. To explore less-labor–intensive methods of measuring care quality, we assessed quality measurement using health insurance claims data linked to the Hospital Based Cancer Registry (HBCR). Methods: We previously developed 206 quality indicators (QIs) to assess cancer care processes in collaboration with clinical experts. Ten of these (stomach cancer, 1; colorectal cancer, 1; lung cancer, 2; breast cancer, 3; liver cancer, 1; and supportive care, 2) could be used for analyzing HBCR health insurance claims data. Patients treated at 7 designated cancer hospitals in Japan in 2010 were included. Their characteristics and tumor stages were obtained from HBCR, and processes of care administered to the patients in 2010–2011 were obtained from health insurance claims data. We calculated a score for each QI based on the proportion of patients receiving care among those eligible for QI. Results: Data of 4,785 patients were analyzed (stomach cancer, 1,181; patients with colorectal cancer, 1,077; lung cancer, 1,091; breast cancer, 1,184; and liver cancer, 252). Quality scores of essential laboratory tests were high; 91% patients underwent the HER2 test for invasive breast cancer and 95% underwent the liver function test using indocyanine green clearance before liver cancer surgery. However, indicator scores for adjuvant chemotherapy were relatively lower at only 59% for stomach cancer patients, 57% for colorectal cancer patients, and 56% for lung cancer patients receiving adjuvant chemotherapy. The supportive care scores had even more scope for improvement as only 43% patients received antiemetics for highly emetic chemotherapy and 66% patients received laxatives along with narcotics. Conclusions: These QIs can be implemented for health insurance claims data linked to HBCR and used to identify the potential target area for improvement. In future, such electronic systems will enable rapid cycles of quality measurement and feedback.

A comparison of liver cancer and lung cancer patients at two Veteran Affairs Medical Centers.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e21642-e21642
Author(s):  
Sejal Kothadia ◽  
Zhen Wang ◽  
Sarah Lee ◽  
Victor Tsu-Shih Chang ◽  
Yucai Wang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Palliative Care ◽  
Liver Cancer ◽  
Cancer Patients ◽  
Care Service ◽  
Palliative Care Service ◽  
Pooled Analysis ◽  
Lung Cancer Patients ◽  
Medical Centers ◽  
Symptom Prevalence

e21642 Background: Little is known about palliative care for liver cancer. In this study, we examined palliative care for liver cancer and lung cancer patients. Methods: In an IRB approved protocol, we reviewed medical records of patients diagnosed with liver cancer who were seen by the palliative care service between 2006 and 2012 at 2 VA medical centers, and matched them to patients with lung cancer by year, KPS, and stage. Veterans were compared by symptom prevalence with the CMSAS and by palliative care interventions. Statistical analyses were performed with SAS Studio Version 3.5. Results: We analyzed a total of 138 male patients at 2 VA centers; 69 with lung cancer and 69 with liver cancer. The mean age in both groups was 65 years and 60% of patients self-identified as a minority. There was a high prevalence of symptoms in both groups. Symptom prevalence differed significantly between liver and lung cancer pts for weight loss and dyspnea at one site, and for feeling drowsy, constipation, at the other site. These differences disappeared in a pooled analysis. During palliative care evaluation, more lung cancer patients received treatment for constipation (n = 44 in lung, 29 in liver, p = 0.0107) and dyspnea treatment (n = 37 in lung, 22 in liver, p = 0.0167). More patients with lung cancer were evaluated by physical therapy (n = 41 in lung, n = 28 in liver, p = 0.0276) and psychiatry (n = 31 in lung, n = 20 in liver, p = 0.032). Conclusions: Differences between lung and liver cancer patients’ symptom prevalence and treatment by palliative care can vary by site. This reinforces the importance of local surveys of symptom prevalence . Further studies should be replicated in other sites.

scholarly journals Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands

Addiction ◽  
2017 ◽  
Vol 112 (11) ◽  
pp. 1909-1917 ◽  
Author(s):  
Vivia V. McCutcheon ◽  
Marc A. Schuckit ◽  
John R. Kramer ◽  
Grace Chan ◽  
Howard J. Edenberg ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Alcohol Use Disorder ◽  
Treatment Seeking ◽  
First Degree Relatives ◽  
Familial Association ◽  
Alcohol Dependent

scholarly journals Volatile nitrosamines and tobacco-specific nitrosamines in the smoke of Thai cigarettes: a risk factor for lung cancer and a suspected risk factor for liver cancer in Thailand

1999 ◽  
Vol 20 (1) ◽  
pp. 133-137 ◽  
Author(s):  
Eugene J. Mitacek ◽  
Klaus D. Brunnemann ◽  
Dietrich Hoffmann ◽  
Thira Limsila ◽  
Maitree Suttajit ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Risk Factor ◽  
Liver Cancer ◽  
Tobacco Specific Nitrosamines ◽  
Volatile Nitrosamines

scholarly journals Dosing of Analgesics for Patients with Liver Cancer or Lung Cancer (S792)

2016 ◽  
Vol 51 (2) ◽  
pp. 458-459
Author(s):  
Milena Monskaya ◽  
Jennifer Pruskowski ◽  
Yleana Garcia ◽  
Victor Chang ◽  
Ellen Olson
Keyword(s):  
Lung Cancer ◽  
Liver Cancer
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