Oral Antibody-Conjugated Liposomes Loaded with Indocyanine Green for Targeted Photoacoustic Imaging Directed Sonodynamic Therapy of H.Pylori

2021 ◽  
Author(s):  
Ruhao Wang ◽  
Cunfeng Song ◽  
Ang Gao ◽  
Qianwen Liu ◽  
Wenbin Guan ◽  
...  
Author(s):  
Lili Pan ◽  
Yu Ma ◽  
Xiaoai Wu ◽  
Huawei Cai ◽  
Feng Qin ◽  
...  

Abstract:: As a group of heterocyclic macrocycle organic natural compounds occurring universally in animal tissues and plants, porphyrins are composed of four modified pyrrole subunits. Porphyrin analogues/derivatives possess multiple biochemical properties because of their unique structures and have been extensively investigated in cancer treatment. Studies have shown that porphyrins and their derivatives have the ability to locate in tumor cells in a variety of human cancers, and these compounds not only exhibit potent therapeutic effects as photodynamic agents but also show promising properties in medicinal imaging, such as MRI, photoacoustic imaging, fluorescence imaging and PET/SPECT imaging. This paper reviews the recent reports of porphyrin derivatives as therapeutic agents used in tumor therapies, such as sonodynamic therapy, photodynamic therapy and radiotherapy, as well as imaging agents for multimodality tumor imaging. The limitations of porphyrin-based compounds in tumor treatments and future prospects are also summarized.


2013 ◽  
Vol 18 (9) ◽  
pp. 096006 ◽  
Author(s):  
Saeid Zanganeh ◽  
Hai Li ◽  
Patrick D. Kumavor ◽  
Umar Alqasemi ◽  
Andres Aguirre ◽  
...  

2018 ◽  
Vol 10 (3) ◽  
Author(s):  
Chengbo Liu ◽  
Jingqin Chen ◽  
Ying Zhu ◽  
Xiaojing Gong ◽  
Rongqin Zheng ◽  
...  

2016 ◽  
Vol 8 (8) ◽  
pp. 5608-5617 ◽  
Author(s):  
Guohao Wang ◽  
Fan Zhang ◽  
Rui Tian ◽  
Liwen Zhang ◽  
Guifeng Fu ◽  
...  

2016 ◽  
Vol 104 (4) ◽  
pp. 825-834 ◽  
Author(s):  
Saji Uthaman ◽  
Joon-suk Bom ◽  
Hyeon Sik Kim ◽  
Johnson V. John ◽  
Hee-Seung Bom ◽  
...  

2014 ◽  
Vol 07 (01) ◽  
pp. 1350029 ◽  
Author(s):  
JUNPING ZHONG ◽  
SIHUA YANG

Contrast agents are attracting a great deal of attention in photoacoustic imaging. Here we introduce an exogenous contrast agent that provides high photoacoustic signal amplitude at the near-infrared wavelength. Our agents consist of Indocyanine green (ICG) and phospholipid–polyethylene glycol (PL–PEG), entitled ICG–PL–PEG nanoparticles. These nanoparticles have overcome numerous limitations of ICG, such as poor aqueous stability, concentration-dependent aggregation and lack of target specificity. ICG–PL–PEG nanoparticles are biocompatible and relatively nontoxic. All the components of ICG–PL–PEG nanoparticles have been approved for human use. Upon pulsed laser irradiation, the nanoparticles are more efficient in producing photoacoustic waves than ICG alone. The results showed that ICG–PL–PEG nanoparticles act as good contrast agents for photoacoustic imaging. These unique ICG–PL–PEG nanoparticles have great potential in clinical applications.


2017 ◽  
Vol 9 (7) ◽  
pp. 1177-1186 ◽  
Author(s):  
Hyungwon Moon ◽  
Haemin Kim ◽  
Changbeom Sim ◽  
Minji Lee ◽  
Jin Ho Chang ◽  
...  

2017 ◽  
Vol 43 (11) ◽  
pp. 2690-2698 ◽  
Author(s):  
Qin Tang ◽  
Shufang Chang ◽  
Zhonghua Tian ◽  
Jiangchuan Sun ◽  
Lan Hao ◽  
...  

2019 ◽  
Vol 1 (2) ◽  
pp. e190035 ◽  
Author(s):  
Nivin N. Nyström ◽  
Lawrence C.M. Yip ◽  
Jeffrey J.L. Carson ◽  
Timothy J. Scholl ◽  
John A. Ronald

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