Non-Invasive Tumor Therapy with Indocyanine Green and Paclitaxel Doubly Loaded Nanoparticles Using Photoacoustic Imaging

2017 ◽  
Vol 9 (7) ◽  
pp. 1177-1186 ◽  
Author(s):  
Hyungwon Moon ◽  
Haemin Kim ◽  
Changbeom Sim ◽  
Minji Lee ◽  
Jin Ho Chang ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Photoacoustic Imaging ◽  
Tumor Therapy ◽  
Invasive Tumor ◽  
Non Invasive

Clearance and Non-Invasive Determination of the Hepatic Extraction of Indocyanine Green in Baboons and Man

1983 ◽  
Vol 64 (2) ◽  
pp. 207-212 ◽  
Author(s):  
S. L. Grainger ◽  
P. W. N. Keeling ◽  
I. M. H. Brown ◽  
J. H. Marigold ◽  
R. P. H. Thompson
Keyword(s):  
Indocyanine Green ◽  
Accurate Determination ◽  
Liver Blood Flow ◽  
Compartment Model ◽  
Hepatic Extraction ◽  
Non Invasive ◽  
Two Compartment Model ◽  
Hepatic Extraction Ratio ◽  
Plasma Disappearance Curve

1. The disposition of an intravenous bolus of indocyanine green (ICG) has been studied in healthy man and baboons using a novel analysis of a two compartment pharmacokinetic model. 2. This analysis enabled the hepatic extraction ratio (ER) of dye to be determined solely from the plasma disappearance curve, and the ER determined did not differ from that measured by hepatic vein catheterization. 3. When compared with clearance measured at steady state, the two compartment model gave a significantly more accurate determination of plasma clearance than did the conventional one compartment model. 4. It is concluded that, in health, liver blood flow may be calculated accurately and noninvasively after a single intravenous injection of ICG.

scholarly journals Photoacoustic imaging enhanced by indocyanine green-conjugated single-wall carbon nanotubes

2013 ◽  
Vol 18 (9) ◽  
pp. 096006 ◽  
Author(s):  
Saeid Zanganeh ◽  
Hai Li ◽  
Patrick D. Kumavor ◽  
Umar Alqasemi ◽  
Andres Aguirre ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Indocyanine Green ◽  
Photoacoustic Imaging ◽  
Single Wall Carbon Nanotubes ◽  
Single Wall Carbon

scholarly journals A Nanodiamond-Based Theranostic Agent for Light-Controlled Intracellular Heating and Nanoscale Temperature Sensing

2020 ◽  
Author(s):  
Yingke Wu ◽  
Md Noor A Alam ◽  
Priyadharshini Balasubramanian ◽  
Anna Ermakova ◽  
Stefan Fischer ◽  
...  
Keyword(s):  
Indocyanine Green ◽  
Biological Activities ◽  
Local Effect ◽  
Biological Processes ◽  
Essential Factor ◽  
Non Invasive ◽  
Theranostic Agent ◽  
External Conditions ◽  
Fluorescent Nanodiamonds ◽  
High Control

Temperature is an essential factor in all biological processes and most of the biological activities are related to temperature. However, information about the temperature in living cells are limited. In photothermal therapy, an emerging cancer treatment due to its high spatial control and non-invasive nature, the local effect of intracellular temperature change is not well understood. Fluorescent nanodiamonds (ND) are a unique carbon material possessing optical defects inside the carbon lattice that enable sensing of temperature on a nanoscale completely independent of external conditions. Herein, we coat ND with polymers to form a nanogel shell around NDs that can absorb indocyanine green, a common photothermal agent, to obtain nanodiamond-nanogel-indocyanine green. Upon irradiation, we not only show successful killing of cancer cells with a high control in space but we are also able to sense the increase in temperature using single NDs as nanothermometers in cells.<br>

scholarly journals The indocyanine green retention test as a non-invasive marker for esophageal varices in patients with hepatocellular carcinoma

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Hsiao-Sheng Lu ◽  
I-Fang Hsin ◽  
Ping-Hsien Chen ◽  
Tsung-Chieh Yang ◽  
Chung-Yu Chang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Indocyanine Green ◽  
Esophageal Varices ◽  
Retention Test ◽  
Non Invasive

scholarly journals Frequency Locked Microtoroid Optical Resonators as a Non-Invasive Tumor Biopsy Alternative

2013 ◽  
Vol 104 (2) ◽  
pp. 528a ◽  
Author(s):  
Judith Su ◽  
Alex Goldberg ◽  
Andrew Raubitschek ◽  
Brian Stoltz ◽  
Scott E. Fraser
Keyword(s):  
Optical Resonators ◽  
Tumor Biopsy ◽  
Invasive Tumor ◽  
Non Invasive
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