Metabolic Fate of NKH477. (2). Blood Concentration, Distribution, Excretion and Effects on Drug-Metabolizing Enzyme System in Rats after Repeated Intravenous Administration.

Shin-ichi MATSUMOTO; Tsuyoshi IRIE; Toshiko EKI; Kouwa YAMASHITA; Hideaki SEKI; Shin-ichi NINOMIYA; Atsushi TAKAO; Miwa OOTUBO; Matsuo TAKAICHI; Yoshio ESUMI

doi:10.2133/dmpk.13.221

Metabolic Fate of NKH477. (2). Blood Concentration, Distribution, Excretion and Effects on Drug-Metabolizing Enzyme System in Rats after Repeated Intravenous Administration.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.13.221 ◽

1998 ◽

Vol 13 (3) ◽

pp. 221-228

Author(s):

Shin-ichi MATSUMOTO ◽

Tsuyoshi IRIE ◽

Toshiko EKI ◽

Kouwa YAMASHITA ◽

Hideaki SEKI ◽

...

Keyword(s):

Intravenous Administration ◽

Blood Concentration ◽

Concentration Distribution ◽

Enzyme System ◽

Metabolic Fate ◽

Drug Metabolizing Enzyme ◽

Metabolizing Enzyme

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Metabolic Fate of a Novel Antiulcer Agent, T-593. (III). Blood Concentration, Distribution, Metabolism, Excretion and Effects on Hepatic Drug Metabolizing Enzyme System after Repeated Oral Administration to Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.13.459 ◽

1998 ◽

Vol 13 (5) ◽

pp. 459-471

Author(s):

Makoto ONODA ◽

Takumi KADOTA ◽

Shinsuke OOYAMA ◽

Hiroko MATSUTANI ◽

Hiroshi SAKAI ◽

...

Keyword(s):

Oral Administration ◽

Blood Concentration ◽

Concentration Distribution ◽

Enzyme System ◽

Metabolic Fate ◽

Hepatic Drug ◽

Drug Metabolizing Enzyme ◽

Antiulcer Agent ◽

Metabolizing Enzyme

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Studies on the Metabolic Fate of Amrubicin Hydrochloride (SM-5887), a Novel Antitumor Agent. (I): Blood Concentration, Distribution, Metabolism and Excretion after a Single Intravenous Administration to Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.13.61 ◽

1998 ◽

Vol 13 (2) ◽

pp. 61-77 ◽

Cited By ~ 1

Author(s):

Shunji NAKAI ◽

Kyoko AKAO ◽

Masaki ITO ◽

Yoshiko MIZUNO ◽

Setsuko KOMURO ◽

...

Keyword(s):

Intravenous Administration ◽

Blood Concentration ◽

Concentration Distribution ◽

Antitumor Agent ◽

Metabolic Fate ◽

Single Intravenous Administration

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Studies on the Metabolic Fate of Amrubicin Hydrochloride (SM-5887), a Novel Antitumor Agent. (III): Blood Concentration, Distribution, Metabolism and Excretion after a Single Intravenous Administration to Dogs.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.13.91 ◽

1998 ◽

Vol 13 (2) ◽

pp. 91-99

Author(s):

Shunji NAKAI ◽

Kyoko AKAO ◽

Masaki ITO ◽

Setsuko KOMURO ◽

Hiroshi KANAMARU ◽

...

Keyword(s):

Intravenous Administration ◽

Blood Concentration ◽

Concentration Distribution ◽

Antitumor Agent ◽

Metabolic Fate ◽

Single Intravenous Administration

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Studies on the Metabolic Fate of Amrubicin Hydrochloride (SM-5887), a Novel Antitumor Agent. (II): Blood Concentration, Distribution, Metabolism and Excretion after Repeated Intravenous Administration to Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.13.78 ◽

1998 ◽

Vol 13 (2) ◽

pp. 78-90

Author(s):

Shunji NAKAI ◽

Kyoko AKAO ◽

Masaki ITO ◽

Hiroshi KANAMARU ◽

Iwao NAKATSUKA

Keyword(s):

Intravenous Administration ◽

Blood Concentration ◽

Concentration Distribution ◽

Antitumor Agent ◽

Metabolic Fate

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Studies on the Metabolic Fate on Ultra Short Acting .BETA.1 Blocker ONO-1101. (2). Plasma Concentration-Time Profile, Distribution, Excretion and Effects on Drug Metabolizing Enzyme Activities after Repeated Intravenous Administration to Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.12.22 ◽

1997 ◽

Vol 12 (1) ◽

pp. 22-30

Author(s):

Ken TSUNEKAWA ◽

Haruo IMAWAKA ◽

Kiyoshi NATSUI ◽

Hiroaki FUJIMOTO ◽

Masatsune ISHIDO ◽

...

Keyword(s):

Plasma Concentration ◽

Intravenous Administration ◽

Enzyme Activities ◽

Time Profile ◽

Metabolic Fate ◽

Short Acting ◽

Concentration Time ◽

Drug Metabolizing Enzyme ◽

Profile Distribution ◽

Metabolizing Enzyme

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Metabolic Fate of Flurazepam 11: A New Potent Metabolite Obtained by In Vitro Liver Drug-Metabolizing Enzyme System

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600641042 ◽

1975 ◽

Vol 64 (10) ◽

pp. 1732-1733

Author(s):

Mamoru Hasegawa ◽

Haruki Takai ◽

Isao Matsubara

Keyword(s):

Enzyme System ◽

Metabolic Fate ◽

Drug Metabolizing Enzyme ◽

Metabolizing Enzyme

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Effect of protein deficiency on the inducibility of the hepatic microsomal drug-metabolizing enzyme system—I

Biochemical Pharmacology ◽

10.1016/0006-2952(73)90165-2 ◽

1973 ◽

Vol 22 (9) ◽

pp. 1005-1014 ◽

Cited By ~ 43

Author(s):

Johnnie R. Hayes ◽

Marcel U.K. Mgbodile ◽

T.Colin Campbell

Keyword(s):

Enzyme System ◽

Protein Deficiency ◽

Drug Metabolizing Enzyme ◽

Metabolizing Enzyme

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Metabolic Fate of YM866, a Novel Fibrinolytic Agent (II). Plasma Concentration, Distribution, Metabolism and Excretion in Rats after Repeated Intravenous Administration.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.11.11 ◽

1996 ◽

Vol 11 (1) ◽

pp. 11-29

Author(s):

Keishi OIKAWA ◽

Hidetaka KAMIMURA ◽

Takashi WATANABE ◽

Saburo HIGUCHI ◽

Satoshi KUROSAWA ◽

...

Keyword(s):

Plasma Concentration ◽

Intravenous Administration ◽

Concentration Distribution ◽

Metabolic Fate ◽

Fibrinolytic Agent

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Metabolic fate of recombinant human tissue plasminogen activator(rt-PA). (1): Blood or plasma concentration, distribution, metabolism and excretion in rats after single intravenous administration.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.3.309 ◽

1988 ◽

Vol 3 (3) ◽

pp. 309-329 ◽

Cited By ~ 1

Author(s):

Seiu IIDA ◽

Masato IWAMOTO ◽

Masayuki SUZUKI ◽

Noriko HISANAGA ◽

Naoki TSUJII ◽

...

Keyword(s):

Plasma Concentration ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Intravenous Administration ◽

Human Tissue ◽

Concentration Distribution ◽

Metabolic Fate ◽

Tissue Plasminogen ◽

Single Intravenous Administration

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Comparison of Some Parameters of the Drug-Metabolizing Enzyme System and Liver Function Tests in Different Hepatic Diseases

Assessment and Management of Hepatobiliary Disease ◽

10.1007/978-3-642-72631-6_31 ◽

1987 ◽

pp. 235-246

Author(s):

T. Horváth

Keyword(s):

Liver Function ◽

Enzyme System ◽

Liver Function Tests ◽

Hepatic Diseases ◽

Function Tests ◽

Drug Metabolizing Enzyme ◽

Metabolizing Enzyme

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