Studies on the Metabolic Fate of Flutamide. (1): Plasma Concentration after Single Administration and Protein Binding in Rats.

Noriko ASAKAWA; Michinori KOYAMA; Yutaka HASHIMOTO; Kouwa YAMASHITA

doi:10.2133/dmpk.10.447

Studies on the Metabolic Fate of Flutamide. (1): Plasma Concentration after Single Administration and Protein Binding in Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.10.447 ◽

1995 ◽

Vol 10 (4) ◽

pp. 447-453 ◽

Cited By ~ 2

Author(s):

Noriko ASAKAWA ◽

Michinori KOYAMA ◽

Yutaka HASHIMOTO ◽

Kouwa YAMASHITA

Keyword(s):

Plasma Concentration ◽

Protein Binding ◽

Single Administration ◽

Metabolic Fate

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Studies on the Metabolic Fate of Levothyroxine-Sodium. (1): Plasma Concentration of T4, T3 and TSH, Protein Binding and the Hepatic Drug-Metabolizing Enzyme Activity in Thyroidectomized Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.9.184 ◽

1994 ◽

Vol 9 (2) ◽

pp. 184-200

Author(s):

Satoshi IWAMURA ◽

Hiromi MORI ◽

Noriyuki KUWAYAMA ◽

Akira FUJIKATA

Keyword(s):

Enzyme Activity ◽

Plasma Concentration ◽

Protein Binding ◽

Levothyroxine Sodium ◽

Metabolic Fate ◽

Hepatic Drug ◽

Drug Metabolizing Enzyme ◽

Metabolizing Enzyme

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Studies on the Metabolic Fate of Levothyroxine-Sodium. (2): Plasma Concentration of T4, T3 and TSH, Urinary Excretion and Protein Binding in Thyroidectomized Dogs.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.9.201 ◽

1994 ◽

Vol 9 (2) ◽

pp. 201-223

Author(s):

Satoshi IWAMURA ◽

Hiromi MORI ◽

Noriyuki KUWAYAMA ◽

Akira FUJIKATA

Keyword(s):

Plasma Concentration ◽

Protein Binding ◽

Urinary Excretion ◽

Levothyroxine Sodium ◽

Metabolic Fate

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Studies on the Metabolic Fate of Felodipine. (I): Absorption, Distribution, Metabolism and Excretion after a Single Administration to Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.6.717 ◽

1991 ◽

Vol 6 (5) ◽

pp. 717-747

Author(s):

Kazuo UNO ◽

Satoru YAMAGAMI ◽

Syoryo HAYASHI ◽

Shigeru TABATA ◽

Yoshio ESUMI ◽

...

Keyword(s):

Single Administration ◽

Metabolic Fate

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Effects of total plasma concentration and age on tolbutamide plasma protein binding

Clinical Pharmacology & Therapeutics ◽

10.1038/clpt.1982.65 ◽

1982 ◽

Vol 31 (4) ◽

pp. 488-493 ◽

Cited By ~ 15

Author(s):

Joseph Adir ◽

Ann K Miller ◽

Robert E Vestal

Keyword(s):

Plasma Concentration ◽

Protein Binding ◽

Plasma Protein Binding ◽

Plasma Protein ◽

Total Plasma ◽

Total Plasma Concentration

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Metabolic fate of simvastatin, an inhibitor of HMG-CoA reductase. (1): Absorption, distribution, metabolism and excretion of (14C) simvastatin after single administration in male rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.5.133 ◽

1990 ◽

Vol 5 (2) ◽

pp. 133-149 ◽

Cited By ~ 1

Author(s):

Naotaka UCHIYAMA ◽

Yuko SAITO ◽

Yayoi KAGAMI ◽

Ken-ichi HARA ◽

Kaoru SAITO ◽

...

Keyword(s):

Male Rats ◽

Single Administration ◽

Metabolic Fate ◽

Hmg Coa Reductase ◽

Coa Reductase

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Studies on the metabolic fate of 15(R)-15-methylprostaglandin E2 (Arbaprostil) in human. (II) - Plasma concentration and urinary excretion of intact drug and its epimer form.

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics ◽

10.3999/jscpt.20.407 ◽

1989 ◽

Vol 20 (2) ◽

pp. 407-413

Author(s):

Hisayuki SEKINO ◽

Noboru NAKAMICHI ◽

Kazuhiro NISHIMIYA ◽

Yasutsugu OHSAWA ◽

Akira OKAZAKI

Keyword(s):

Plasma Concentration ◽

Urinary Excretion ◽

Metabolic Fate ◽

Intact Drug

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Metabolic Fate of YM866, a Novel Fibrinolytic Agent (II). Plasma Concentration, Distribution, Metabolism and Excretion in Rats after Repeated Intravenous Administration.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.11.11 ◽

1996 ◽

Vol 11 (1) ◽

pp. 11-29

Author(s):

Keishi OIKAWA ◽

Hidetaka KAMIMURA ◽

Takashi WATANABE ◽

Saburo HIGUCHI ◽

Satoshi KUROSAWA ◽

...

Keyword(s):

Plasma Concentration ◽

Intravenous Administration ◽

Concentration Distribution ◽

Metabolic Fate ◽

Fibrinolytic Agent

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Studies on the Metabolic Fate of Lamivudine (II): Tissue Distribution, Transfer into Fetus and Milk, Plasma Protein Binding and Distribution to Erythrocytes of Lamivudine in Rats.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.12.92 ◽

1997 ◽

Vol 12 (2) ◽

pp. 92-101

Author(s):

Takatoshi TAKUBO ◽

Seiji HIRAYAMA ◽

Takahito MORIYA ◽

Yoshiyuki MINAMIDE ◽

Toshihiro KATO ◽

...

Keyword(s):

Protein Binding ◽

Tissue Distribution ◽

Plasma Protein Binding ◽

Plasma Protein ◽

Metabolic Fate

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Studies on the Metabolic Fate of Leukotriene Antagonist ONO-1078. (3). Absorption, Distribution and Excretion after Single Administration to Beagle Dogs.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.8.39 ◽

1993 ◽

Vol 8 (1) ◽

pp. 39-47

Author(s):

Masatsune ISHIDO ◽

Kimiko SAKAGUCHI ◽

Mayumi TAKAMOTO ◽

Masafumi SAWADA ◽

Hideki AISHITA ◽

...

Keyword(s):

Single Administration ◽

Beagle Dogs ◽

Metabolic Fate ◽

Leukotriene Antagonist

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Metabolic fate of recombinant human tissue plasminogen activator(rt-PA). (1): Blood or plasma concentration, distribution, metabolism and excretion in rats after single intravenous administration.

Drug Metabolism and Pharmacokinetics ◽

10.2133/dmpk.3.309 ◽

1988 ◽

Vol 3 (3) ◽

pp. 309-329 ◽

Cited By ~ 1

Author(s):

Seiu IIDA ◽

Masato IWAMOTO ◽

Masayuki SUZUKI ◽

Noriko HISANAGA ◽

Naoki TSUJII ◽

...

Keyword(s):

Plasma Concentration ◽

Plasminogen Activator ◽

Tissue Plasminogen Activator ◽

Intravenous Administration ◽

Human Tissue ◽

Concentration Distribution ◽

Metabolic Fate ◽

Tissue Plasminogen ◽

Single Intravenous Administration

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