Role of Lipotropes in Mammary Carcinogenesis

1996 ◽  
Author(s):  
Chung S. Park
Keyword(s):  
Mammary Carcinogenesis

scholarly journals The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis

Oncogene ◽  
2015 ◽  
Vol 34 (50) ◽  
pp. 6105-6114 ◽  
Author(s):  
J M Park ◽  
T Wu ◽  
A R Cyr ◽  
G W Woodfield ◽  
J P De Andrade ◽  
...  
Keyword(s):  
Mammary Carcinogenesis ◽  
Cancer Growth

Effects of the farnesyl transferase inhibitor R115777 (Zarnestra) on mammary carcinogenesis: prevention, therapy, and role of HaRas mutations

2006 ◽  
Vol 5 (4) ◽  
pp. 1073-1078 ◽  
Author(s):  
Ronald A. Lubet ◽  
Konstantin Christov ◽  
Ming You ◽  
Ruisheng Yao ◽  
Vernon E. Steele ◽  
...  
Keyword(s):  
Mammary Carcinogenesis ◽  
Farnesyl Transferase ◽  
Prevention Therapy ◽  
Farnesyl Transferase Inhibitor

The Role of the Estrogen Receptor Coactivator, Amplified in Breast Cancer 1 (AIB1), in Her2/neu-Initiated Mouse Mammary Carcinogenesis and Tamoxifen Resistance.

2008 ◽  
Vol 78 (Suppl_1) ◽  
pp. 103-103
Author(s):  
Maddalena T. Tilli ◽  
Mark P. Fereshteh ◽  
Kathleen M. Torre ◽  
Anna T. Riegel ◽  
Priscilla A. Furth
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Tamoxifen Resistance ◽  
Mammary Carcinogenesis

scholarly journals Induction of experimental mammary carcinogenesis in rats with 7,12-dimethylbenz(a)anthracene

2004 ◽  
Vol 59 (5) ◽  
pp. 257-261 ◽  
Author(s):  
Alfredo Carlos S. D. Barros ◽  
Elisa Naomi K. Muranaka ◽  
Lincon Jo Mori ◽  
Christina Helena T. Pelizon ◽  
Kyoshi Iriya ◽  
...  
Keyword(s):  
Animal Model ◽  
Light Microscopy ◽  
Breast Tumor ◽  
Mammary Carcinogenesis ◽  
Mammary Glands ◽  
Female Rats ◽  
Histopathological Analysis ◽  
Breast Carcinomas ◽  
Sprague Dawley

PURPOSE: To test an experimental model of chemical mammary carcinogenesis induction in rats. METHODS: Twenty young virgin Sprague-Dawley female rats, aged 47 days, received 20 mg of 7,12-dimethylbenz(a)anthracene (DMBA) intragastrically by gavage. Afterwards, at 8 and 13 weeks, their mammary glands were examined. At the end of the experiment, the animals were sacrificed, and the mammary tumors were measured and weighed. Tumor fragments were analyzed using light microscopy. RESULTS: Eight weeks after DMBA injection, 16 rats presented at least 1 breast tumor (80%). After 13 weeks, all of them (100%) developed breast carcinomas that were confirmed by histopathological analysis. CONCLUSION: This experimental animal model of chemical mammary induced carcinogenesis is feasible and can be used in further experiments on the role of tumorigenic biomodulator substances.

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