Transport of a pH-Sensitive Polymer in Porous Media for Novel Mobility-Control Applications

Author(s):  
Choi Suk Kyoon ◽  
Youn Mee Ermel ◽  
Steven Lawrence Bryant ◽  
Chun Huh ◽  
Mukul Mani Sharma
Soft Matter ◽  
2017 ◽  
Vol 13 (41) ◽  
pp. 7571-7577 ◽  
Author(s):  
Monika Kluzek ◽  
Arwen I. I. Tyler ◽  
Shiqi Wang ◽  
Rongjun Chen ◽  
Carlos M. Marques ◽  
...  

Cubosomes consist in submicron size particles of lipid bicontinuous cubic phases stabilized by surfactant polymers.


2010 ◽  
Vol 7 (4) ◽  
pp. 1098-1107 ◽  
Author(s):  
Pierre Simard ◽  
Jean-Christophe Leroux

Author(s):  
EMMANUEL O. OLORUNSOLA ◽  
IMO E. UDOH ◽  
STEPHEN O. MAJEKODUNMI ◽  
INIOBONG J. ODIONG ◽  
UWAKMFON O. EBONG

Objective: This work was aimed at formulating omeprazole tablets using afzelia gum as a binder that is capable of inhibiting the gastric degradation of the drug. Methods: Afzelia gum at different concentrations of 0, 5, 10, 15, 20 and 30% was used as a binder to formulate omeprazole tablets. The tablets were formulated by direct compression and the batches labelled F1 to F6 respectively. A batch containing 15% hydroxypropyl methylcellulose (F7) was also formulated. The tablets were characterized; and dissolution in a pH 1.2 dissolution medium over 120 min period was studied. Aliquots taken every 20 min were analyzed by ultraviolet spectrophotometry to determine the amount of drug released and not degraded. Results: Amounts of drug released and not degraded at time 120 min were 53.1%, 57.3%, 57.8%, 58.8%, 62.1%, 83.4% and 90.0% for F1 to F7 respectively. Conclusion: Afzelia gum at a concentration of 30% is suitable for use as a binder in tablet formulation of omeprazole to ensure substantial inhibition of gastric degradation of the drug.


1987 ◽  
Vol 35 (11) ◽  
pp. 4568-4573 ◽  
Author(s):  
JUN-ICHI ANZAI ◽  
MASAHIKO SHIMADA ◽  
HONGDA Fu ◽  
TETSUO OSA

2018 ◽  
Vol 10 (24) ◽  
pp. 20876-20883 ◽  
Author(s):  
Naruphorn Dararatana ◽  
Farzad Seidi ◽  
Daniel Crespy

2018 ◽  
Vol 140 (10) ◽  
Author(s):  
Chuan Lu ◽  
Wei Zhao ◽  
Yongge Liu ◽  
Xiaohu Dong

Oil-in-water (O/W) emulsions are expected to be formed in the process of surfactant flooding for heavy oil reservoirs in order to strengthen the fluidity of heavy oil and enhance oil recovery. However, there is still a lack of detailed understanding of mechanisms and effects involved in the flow of O/W emulsions in porous media. In this study, a pore-scale transparent model packed with glass beads was first used to investigate the transport and retention mechanisms of in situ generated O/W emulsions. Then, a double-sandpack model with different permeabilities was used to further study the effect of in situ formed O/W emulsions on the improvement of sweep efficiency and oil recovery. The pore-scale visualization experiment presented an in situ emulsification process. The in situ formed O/W emulsions could absorb to the surface of pore-throats, and plug pore-throats through mechanisms of capture-plugging (by a single emulsion droplet) and superposition-plugging or annulus-plugging (by multiple emulsion droplets). The double-sandpack experiments proved that the in situ formed O/W emulsion droplets were beneficial for the mobility control in the high permeability sandpack and the oil recovery enhancement in the low permeability sandpack. The size distribution of the produced emulsions proved that larger pressures were capable to displace larger O/W emulsion droplets out of the pore-throat and reduce their retention volumes.


Sign in / Sign up

Export Citation Format

Share Document