Minimal Scar Formation After Orthopaedic Skin Incisions Along Main Folding Lines

2019 ◽  
Vol 101 (5) ◽  
pp. 392-399 ◽  
Author(s):  
Gottfried Lemperle ◽  
Dieter Knapp ◽  
Mayer Tenenhaus
Keyword(s):  
Scar Formation ◽  
Minimal Scar

A REVIEW ARTICLE ON DUSHTA VRANA AND ITS MANAGEMENT IN AYURVEDA

2020 ◽  
Vol 8 (04) ◽  
Author(s):  
Sharad Bajaj
Keyword(s):  
Wound Healing ◽  
Foreign Body ◽  
Review Article ◽  
Scar Formation ◽  
Normal Process ◽  
Factors Affecting ◽  
Surgical Practice ◽  
Contaminated Wound ◽  
Minimal Scar

Dushta Vrana is a common encountered problem faced in surgical practice. The presence of Dushta Vrana can damage the condition of the patient with different complications and may become fatal. Factors affecting on wound are slough, infection and foreign body, which can delay the normal process of healing. A healthy wound in a heals earlier as compared to a contaminated wound. Therefore it is important to keep the wound clean during the various stages of its healing. Good wound healing with minimal scar formation with least pain effectively is the prime motto of every surgeon. Acharya Sushruta has ornately explaind six types of Dushta Vrana and management of Dushta Vrana is included by number of drugs, broadly classified into Vranashaodhana and Vrana ropana.

Increased Oral Fibroblast Lifespan Is Telomerase-independent

2009 ◽  
Vol 88 (10) ◽  
pp. 916-921 ◽  
Author(s):  
S. Enoch ◽  
I. Wall ◽  
M. Peake ◽  
L. Davies ◽  
J. Farrier ◽  
...  
Keyword(s):  
Wound Healing ◽  
Telomeric Repeat ◽  
Scar Formation ◽  
Skin Fibroblasts ◽  
Telomeric Repeat Amplification Protocol ◽  
Phenotypic Characteristics ◽  
Amplification Protocol ◽  
Population Doublings ◽  
Minimal Scar ◽  
Mucosal Wound

Oral mucosal wound-healing is characterized by rapid re-epithelialization and remodeling, with minimal scar formation. This may be attributed to the distinct phenotypic characteristics of the resident fibroblasts. To test this hypothesis, we investigated patient-matched oral mucosal and skin fibroblasts. Compared with skin fibroblasts, oral mucosal fibroblasts had longer proliferative lifespans, underwent more population doublings, and experienced senescence later, which was directly related to longer telomere lengths within oral mucosal fibroblasts. The presence of these longer telomeres was independent of telomerase expression, since both oral oral mucosal fibroblasts and skin fibroblasts were negative for active telomerase, as assessed according to the Telomeric Repeat Amplification Protocol. This study has demonstrated that, compared with skin fibroblasts, oral mucosal fibroblasts are ‘younger’, with a more embryonic/fetal-like phenotype that may provide a notable advantage for their ability to repair wounds in a scarless fashion.

Sign in / Sign up

Export Citation Format

Share Document