AB072. Functional impact of the lateral posterior nucleus on the mouse primary visual cortex

2018 ◽  
Vol 3 ◽  
pp. AB072-AB072
Author(s):  
Umit Keysan ◽  
Christian Casanova
Keyword(s):  
Visual Cortex ◽  
Primary Visual Cortex ◽  
Functional Impact ◽  
Lateral Posterior ◽  
Lateral Posterior Nucleus

scholarly journals Spatial clustering of inhibition in mouse primary visual cortex

2019 ◽  
Author(s):  
Pawan Bista ◽  
Rinaldo D. D’Souza ◽  
Andrew M. Meier ◽  
Weiqing Ji ◽  
Andreas Burkhalter
Keyword(s):  
Visual Cortex ◽  
Long Range ◽  
Primary Visual Cortex ◽  
Pyramidal Neurons ◽  
Spatial Clustering ◽  
Muscarinic Acetylcholine Receptor ◽  
Feature Maps ◽  
Lateral Posterior ◽  
Mouse Visual Cortex ◽  
Relative Excitation

SUMMARYWhether mouse visual cortex contains orderly feature maps is debated. The overlapping pattern of geniculocortical (dLGN) inputs with M2 muscarinic acetylcholine receptor-rich patches in layer 1 (L1) suggests a non-random architecture. Here, we found that L1 inputs from the lateral posterior thalamus (LP) avoid patches and target interpatches. Channelrhodopsin-assisted mapping of EPSCs in L2/3 shows that the relative excitation of parvalbumin-expressing interneurons (PVs) and pyramidal neurons (PNs) by dLGN, LP and cortical feedback are distinct and depend on whether the neurons reside in clusters aligned with patches or interpatches. Paired recordings from PVs and PNs shows that unitary IPSCs are larger in interpatches than patches. The spatial clustering of inhibition is matched by dense clustering of PV-terminals in interpatches. The results show that the excitation/inhibition balance across V1 is organized into patch and interpatch subnetworks which receive distinct long-range inputs and are specialized for the processing of distinct spatiotemporal features.

Visual response characteristics in lateral and medial subdivisions of the rat pulvinar

2020 ◽  
Author(s):  
Andrzej T. Foik ◽  
Leo R. Scholl ◽  
Georgina A. Lean ◽  
David C. Lyon
Keyword(s):  
Visual Cortex ◽  
Superior Colliculus ◽  
The Other ◽  
Motion Processing ◽  
Visual Feature ◽  
Feature Processing ◽  
Thalamic Relay ◽  
Lateral Posterior ◽  
Lateral Posterior Nucleus ◽  
Single Cell Response

AbstractThe pulvinar is a higher-order thalamic relay and a central component of the extrageniculate visual pathway, with input from the superior colliculus and visual cortex and output to all of visual cortex. Rodent pulvinar, more commonly called the lateral posterior nucleus (LP), consists of three highly-conserved subdivisions, and offers the advantage of simplicity in its study compared to more subdivided primate pulvinar. Little is known about receptive field properties of LP, let alone whether functional differences exist between different LP subdivisions, making it difficult to understand what visual information is relayed and what kinds of computations the pulvinar might support. Here, we characterized single-cell response properties in two V1 recipient subdivisions of rat pulvinar, the rostromedial (LPrm) and lateral (LPl), and found that a fourth of the cells were selective for orientation, compared to half in V1, and that LP tuning widths were significantly broader. Response latencies were also significantly longer and preferred size more than three times larger on average than in V1; the latter suggesting pulvinar as a source of spatial context to V1. Between subdivisons, LPl cells preferred higher temporal frequencies, whereas LPrm showed a greater degree of direction selectivity and pattern motion detection. Taken together with known differences in connectivity patterns, these results suggest two separate visual feature processing channels in the pulvinar, one in LPl related to higher speed processing which likely derives from superior colliculus input, and the other in LPrm for motion processing derived through input from visual cortex.Significance StatementThe pulvinar has a perplexing role in visual cognition as no clear link has been found between the functional properties of its neurons and behavioral deficits that arise when it is damaged. The pulvinar, called the lateral posterior nucleus (LP) in rats, is a higher order thalamic relay with input from the superior colliculus and visual cortex and output to all of visual cortex. By characterizing single-cell response properties in anatomically distinct subdivisions we found two separate visual feature processing channels in the pulvinar, one in lateral LP related to higher speed processing which likely derives from superior colliculus input, and the other in rostromedial LP for motion processing derived through input from visual cortex.

Visual cortex damage-induced growth of retinal axons into the lateral posterior nucleus of the cat

1993 ◽  
Vol 10 (4) ◽  
pp. 747-752 ◽  
Author(s):  
Bertram R. Payne ◽  
Heather A. Foley ◽  
Stephen G. Lomber
Keyword(s):  
Visual Cortex ◽  
Visual Field ◽  
Cortical Areas ◽  
Retinal Axons ◽  
Lateral Posterior ◽  
Lateral Posterior Nucleus ◽  
Visual Field Maps ◽  
Areas 17 And 18 ◽  
Adult Cats ◽  
Visual Cortical

AbstractAblation of visual cortical areas 17 and 18 in neonatal and young adult cats induces novel retinal projections to terminate bilaterally in the lateral posterior nucleus (LP) at a position ventromedial from the medial interlaminar nucleus. Comparison with the visual-field maps of LP indicate that the terminations are focussed on the representation of the visual-field center.

scholarly journals Structural and functional connectivity between the lateral posterior-pulvinar complex and primary visual cortex in the ferret

2016 ◽  
Vol 43 (2) ◽  
pp. 230-244 ◽  
Author(s):  
Chunxiu Yu ◽  
Kristin K. Sellers ◽  
Susanne Radtke-Schuller ◽  
Jinghao Lu ◽  
Lei Xing ◽  
...  
Keyword(s):  
Visual Cortex ◽  
Functional Connectivity ◽  
Primary Visual Cortex ◽  
Lateral Posterior
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