CRIMEAN HAEMORRHAGIC FEVER IN A CHILD AFTER A VISIT TO CRIMEA

This article contains additional information on the features of the clinical picture of Crimean hemorrhagic fever (CHF) in children, the ongoing activity of CHF virus circulation in the territory of the Republic of Crimea, confirms the possibility of imported cases of CHF in non-endemic regions, which is associated with the likely risks of nosocomial and intrafamilial cases of this infection. The data on the course of the disease, clinical and laboratory diagnostic examination of a child infected with CHF in the Crimea are presented.

MANAJEMEN PEMBELAJARAN DALAM JARINGAN (DARING) PADA MASA COVID-19 DI SMAN 2 PALANGKA RAYA

Abstrak: Penelitian ini bertujuan mendeskripsikan Manajemen Pembelajaran Dalam Jaringan (Daring) Pada Masa Covid-19 di SMAN 2 Palangka Raya. Teknik pengumpulan data dilakukan dengan observasi, wawancara, dan dokumentasi. Analisis data dilakukan dengan cara pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Pengabsahan data penelitian ini menggunakan teknik triangulasi. Hasil penelitian ini menunjukkan bahwa: (1) Perencanaan pembelajaran daring meliputi: mendata kondisi siswa, melakukan IHT, sosialisasi perangkat pembelajaran, sosialisasi penggunaan aplikasi pembelajaran dan sosialisasi kepada orang tua siswa, serta perencanaan penyusunan perangkat pembelajaran, (2) Pelaksanaan pembelajaran daring sudah berjalan dengan baik menggunakan berbagai aplikasi pembelajaran daring, (3) Pengawasan pembelajaran daring dilakukan oleh pihak sekolah dan pengawas pembina dari Dinas Pendidikan Provinsi Kalimantan Tengah, (4) Evaluasi pembelajaran daring dilakukan oleh kepala sekolah sebagai penanggung jawab dengan memantau setiap kegiatan yang sedang berjalan dan melakukan supervisi agar sesuai dengan rencana, dan (5) Faktor pendukung meliputi: tersedianya fasilitas seperti: laptop, gadget, komputer, jaringan internet, dan kuota yang dapat mendukung pembelajaran daring; sedangkan faktor penghambat adalah tidak stabilnya jaringan internet. Abstract: This study aims to describe Online Learning Management during the Covid-19 Period at SMAN 2 Palangka Raya. Data collection techniques were carried out by observation, interviews, and documentation. Data analysis was carried out by collecting data, reducing data, presenting data, and drawing conclusions. Validation of this research data using triangulation technique. The results of this study indicate that: (1) Online learning planning includes: recording student conditions, conducting IHT, socialization of learning tools, socialization of the use of learning applications and socialization to parents of students, as well as planning for the preparation of learning tools, (2) The implementation of online learning has been running properly using various online learning applications, (3) Supervision of online learning is carried out by the school and supervisory supervisors from the Central Kalimantan Provincial Education Office, (4) Evaluation of online learning is carried out by the principal as the person in charge by monitoring every ongoing activity and conducting supervision so that it is in accordance with the plan, and (5) supporting factors include: the availability of facilities such as: laptops, gadgets, computers, internet networks, and quotas that can support online learning; while the inhibiting factor is the unstable internet network.

Morphoneotectonics of the Abruzzo Periadriatic Area (Central Italy): Morphometric Analysis and Morphological Evidence of Tectonics Features

Drainage basin-scale morphometric analysis and morphological evidence of tectonics represent helpful tools to evaluate and investigate morphoneotectonic processes in tectonically active regions. In this perspective, we applied an integrated analysis to the Abruzzo Periadriatic Area, between the Tronto and Sinello rivers (Central Italy). It involved morphometric analysis, structural geomorphological field mapping, and detailed analysis of fluvial terraces. Geomorphic indexes and markers (e.g., Irta, SL index, ksn, and knickpoints) were used in this study to detect the response of landscapes to drainage systems’ unsteadiness and tectonic deformation processes, possibly induced by the ongoing activity of the buried tectonic structures. Furthermore, the investigation of morphological field evidence of tectonics, integrated with the analysis of fluvial terraces’ spatial and temporal arrangement, was performed to assign relative, geomorphologically-based, age constraints of the landscape evolution. The resulting data allowed us to define domains affected by different morphostructural and morphoneotectonic processes, related to the impact and ongoing activity of the five detected families of structural elements (S1, F1, F2, F3, and F4), mainly characterized by compressive, extensional, and transtensive kinematics. Finally, this study could represent a scientific basis for integrating morphometric, fluvial, and tectonic geomorphology analysis to better define the main phases of the landscape evolution and the impact of morphoneotectonic processes on fluvial environments in uplifting piedmont areas.

Awake perception is associated with dedicated neuronal assemblies in cerebral cortex

Neural activity in sensory cortex combines stimulus responses and ongoing activity, but it remains unclear whether they reflect the same underlying dynamics or separate processes. Here we show that during wakefulness, the neuronal assemblies evoked by sounds in the auditory cortex and thalamus are specific to the stimulus and distinct from the assemblies observed in ongoing activity. In contrast, during anesthesia, evoked assemblies are indistinguishable from ongoing assemblies in cortex, while they remain distinct in the thalamus. A strong remapping of sensory responses accompanies this dynamical state change produced by anesthesia. Together, these results show that the awake cortex engages dedicated neuronal assemblies in response to sensory inputs, which we suggest is a network correlate of sensory perception.One-Sentence SummarySensory responses in the awake cortex engage specific neuronal assemblies that disappear under anesthesia.

Action bids in children with speech impairments

The paper illustrates a practice, which we have called ‘marking’, observed in play interactions between parents and children with Down syndrome (DS) aged 3–8 years. Markings are minimal turns that rely on prosody, embodied resources and indexicality to foreground events within an ongoing activity and convey a stance toward them. Markings can be both retrospective and prospective (i.e. referring to a just-occurred or an incipient event). As first pair parts, they are open action bids that prompt recipients to display their co-orientation towards the referent. Responses from parents (i.e. second markings) can take the form of repeats or expansions; after prospective marking the recipient can also add support to the incipient activity the child has marked. We discuss marking as the core constituent of a larger family of actions for ‘sharing noteworthiness’, but also as a designedly undetermined action bid with specific conversational uses for children and adults alike.

Learning to Manage Breadth: Experience as Repetition and Adaptation

We examine how experience-induced adaptations that affect the breadth of an ongoing activity affect performance. The research on organizational learning suggests that accumulating experience, both from repetition and adaptation at the activity level, improves outcomes. Yet, findings on the effects of increasing breadth—the number of different processes making up an activity—are mixed. Greater breadth exposes organizations to diverse activities. It also generates an additional need for coordination that may undermine performance. We examine the joint effect of experience and breadth on waste reduction for U.S. manufacturing facilities managing their toxic waste from 1991 to 2014. These facilities manage toxic waste on a chemical by chemical basis. We find a detrimental effect of breadth on performance that is highest for facilities with low experience; however, this effect is moderated by experience with the waste management activity. Because most facilities manage toxic waste from several chemicals, we also see spillovers—in terms of both learning benefits and the costs of increasing breadth. When a facility expands waste management breadth anywhere, performance decreases for the focal chemical. Yet, this spillover effect of breadth decreases for activities where the facility has accrued more experience. Our research clarifies when facilities should consider adding breadth to a routine activity and why performance in the proximate period may falter as the organization learns and improves in the longer term.

Molecular fossils illuminate the evolution of retroviruses following a macroevolutionary transition from land to water

The ancestor of cetaceans underwent a macroevolutionary transition from land to water early in the Eocene Period >50 million years ago. However, little is known about how diverse retroviruses evolved during this shift from terrestrial to aquatic environments. Did retroviruses transition into water accompanying their hosts? Did retroviruses infect cetaceans through cross-species transmission after cetaceans invaded the aquatic environments? Endogenous retroviruses (ERVs) provide important molecular fossils for tracing the evolution of retroviruses during this macroevolutionary transition. Here, we use a phylogenomic approach to study the origin and evolution of ERVs in cetaceans. We identify a total of 8,724 ERVs within the genomes of 25 cetaceans, and phylogenetic analyses suggest these ERVs cluster into 315 independent lineages, each of which represents one or more independent endogenization events. We find that cetacean ERVs originated through two possible routes. 298 ERV lineages may derive from retrovirus endogenization that occurred before or during the transition from land to water of cetaceans, and most of these cetacean ERVs were reaching evolutionary dead-ends. 17 ERV lineages are likely to arise from independent retrovirus endogenization events that occurred after the split of mysticetes and odontocetes, indicating that diverse retroviruses infected cetaceans through cross-species transmission from non-cetacean mammals after the transition to aquatic life of cetaceans. Both integration time and synteny analyses support the recent or ongoing activity of multiple retroviral lineages in cetaceans, some of which proliferated into hundreds of copies within the host genomes. Although ERVs only recorded a proportion of past retroviral infections, our findings illuminate the complex evolution of retroviruses during one of the most marked macroevolutionary transitions in vertebrate history.

Participating researcher or researching participant?

The article explores different participant positions that are available to researchers of social interaction during the collection of mobile video data. In the data presented, participants are engaged in outdoor activities that essentially involve some form and amount of mobility. The authors analyse the positions they have adopted in collecting data involving groups of mobile participants. The positions have varied depending on whether the activities allow, or even assume, researchers to draw on some specific participant knowledge. The article focuses on moments of adjustment during which the authors, as researchers collecting data, evidently make decisions about what to record and how to participate in the ongoing activity, and which thus reflect their spontaneous, negotiable and planned participation on site. As researchers of social interaction increasingly draw on data that involve mobility, it is pertinent to consider the possible positions that they may adopt and the practices that they employ in the collection and analysis of such data.

Experience-dependent plasticity modulates ongoing activity in the antennal lobe and enhance odor representations

ABSTRACTOngoing neural activity has been observed across several brain regions and thought to reflect the internal state of the brain. Yet, it is not fully understood how ongoing brain activity interacts with sensory experience and shape sensory representations. Here, we show that projection neurons of the fruit fly antennal lobe exhibit spatiotemporally organized ongoing activity in the absence of odor stimulation. Upon repeated exposure to odors, we observe a gradual and long-lasting decrease in the amplitude and frequency of spontaneous calcium events, as well as a reorganization of correlations between olfactory glomeruli during ongoing activity. Accompanying these plastic changes, we find that repeated odor experience reduces trial-to-trial variability and enhances the specificity of odor representations. Our results reveal a previously undescribed experience-dependent plasticity of ongoing and sensory driven activity at peripheral levels of the fruit fly olfactory system.