Evaluation of pregnant women at risk of preterm delivery by correlating ultrasound markers with Insulin-like growth factor binding protein-1

Gineco eu ◽  
2014 ◽  
Vol 10 (2) ◽  
pp. 62-65
Author(s):  
Goganau A.
2008 ◽  
Vol 279 (3) ◽  
pp. 279-283 ◽  
Author(s):  
Ozlem Altinkaya ◽  
Tayfun Gungor ◽  
Mustafa Ozat ◽  
Nuri Danisman ◽  
Leyla Mollamahmutoglu

Author(s):  
P C O'Leary ◽  
M Longley

Serum concentrations of insulin-like growth factor binding protein-1 (IGFBP-1) were measured in men and in non-pregnant and pregnant women. Peak serum IGFBP-1 levels occurred mid-gestation followed by a slight decline towards term. Women with gestational diabetes had higher serum IGFBP-1 concentrations than apparently healthy women at comparable gestation. Following administration of an oral glucose load, serum IGFBP-1 concentrations were decreased within 2 h in men and in pregnant women while IGF-I levels remained constant. These results suggested that IGFBP-1 regulates IGF-I activity in pregnancy in a similar manner to that in the non-pregnant state.


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