STUDIES ON METFORMIN HYDROCHLORIDE AND ALPHA-CYCLODEXTRIN INCLUSION COMPLEXES

S. Lizy Roselet,; Dr J Premakumari

doi:10.18510/gctl.2015.117

STUDIES ON METFORMIN HYDROCHLORIDE AND ALPHA-CYCLODEXTRIN INCLUSION COMPLEXES

Green Chemistry & Technology Letters ◽

10.18510/gctl.2015.117 ◽

2015 ◽

Vol 1 (01) ◽

pp. 48-53 ◽

Cited By ~ 1

Author(s):

S. Lizy Roselet, ◽

Dr J Premakumari

Keyword(s):

Type 2 Diabetes ◽

Inclusion Complexes ◽

Spectroscopic Studies ◽

Metformin Hydrochloride ◽

Phase Solubility ◽

Solution State ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion ◽

Solubility Studies

Metformin hydrochloride is an oral antihyperglycemic drug used in the management of type-2 diabetes. Inclusion complexes were prepared between Metformin hydrochloride and alpha- cyclodextrin in solid and solution state. Inclusion complexes were characterised using UV-VIS, Fluorescence and FTIR Spectroscopic Studies. Phase solubility studies were carried out which determined the 1:1 stoichiometry for the formation of inclusion complexes.

Download Full-text

Phase solubility studies and stability of cholesterol/β-cyclodextrin inclusion complexes

Journal of the Science of Food and Agriculture ◽

10.1002/jsfa.4425 ◽

2011 ◽

Vol 91 (14) ◽

pp. 2551-2557 ◽

Cited By ~ 37

Author(s):

Cristina dos Santos ◽

María P Buera ◽

María F Mazzobre

Keyword(s):

Inclusion Complexes ◽

Phase Solubility ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion ◽

Phase Solubility Studies ◽

Solubility Studies

Download Full-text

Astemizole/Cyclodextrin Inclusion Complexes: Phase Solubility, Physicochemical Characterization and Molecular Modeling Studies

Journal of Solution Chemistry ◽

10.1007/s10953-008-9277-z ◽

2008 ◽

Vol 37 (6) ◽

pp. 875-893 ◽

Cited By ~ 5

Author(s):

Mahmoud M. Al Omari ◽

Mohammad B. Zughul ◽

J. Eric D. Davies ◽

Adnan A. Badwan

Keyword(s):

Molecular Modeling ◽

Inclusion Complexes ◽

Physicochemical Characterization ◽

Phase Solubility ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion ◽

Modeling Studies ◽

Molecular Modeling Studies

Download Full-text

Studies of cyclodextrin inclusion complexes. I. The salbutamol-cyclodextrin complex as studied by phase solubility and DSC

International Journal of Pharmaceutics ◽

10.1016/0378-5173(90)90132-n ◽

1990 ◽

Vol 63 (3) ◽

pp. 259-266 ◽

Cited By ~ 131

Author(s):

H MARQUES ◽

J HADGRAFT ◽

I KELLAWAY

Keyword(s):

Inclusion Complexes ◽

Phase Solubility ◽

Cyclodextrin Complex ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion

Download Full-text

Characterization of the 13-cis-retinoic acid/cyclodextrin inclusion complexes by phase solubility, photostability, physicochemical and computational analysis

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2005.01.021 ◽

2005 ◽

Vol 25 (1) ◽

pp. 49-56 ◽

Cited By ~ 63

Author(s):

K.L. Yap ◽

X. Liu ◽

J.C. Thenmozhiyal ◽

P.C. Ho

Keyword(s):

Retinoic Acid ◽

Inclusion Complexes ◽

Computational Analysis ◽

Phase Solubility ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion

Download Full-text

Spectroscopic studies on the cyclodextrin inclusion complexes of aromatic compounds and radicals

Supramolecular Chemistry ◽

10.1080/10610279308029818 ◽

1993 ◽

Vol 2 (4) ◽

pp. 277-282 ◽

Cited By ~ 3

Author(s):

Makoto Aoyagi ◽

Masafumi Ata ◽

Yasuhiko Gondo ◽

Yoshihiro Kubozono ◽

Yasunobu Suzuki

Keyword(s):

Inclusion Complexes ◽

Aromatic Compounds ◽

Spectroscopic Studies ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion

Download Full-text

Characterization of mitotane (o,p′-DDD) – cyclodextrin inclusion complexes: Phase-solubility method and NMR

Annales Pharmaceutiques Françaises ◽

10.1016/j.pharma.2013.02.001 ◽

2013 ◽

Vol 71 (3) ◽

pp. 186-192 ◽

Cited By ~ 3

Author(s):

R. Alfonsi ◽

D. Attivi ◽

A. Astier ◽

M. Socha ◽

S. Morice ◽

...

Keyword(s):

Inclusion Complexes ◽

Phase Solubility ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion ◽

Solubility Method

Download Full-text

Environmental Effects on Molecular Propcrtics of Organic Compounds. Part II. β-Cyclodextrin Inclusion Complexes with Cieinamic Acids

Molecular Crystals and Liquid Crystals ◽

10.1080/00268948808070590 ◽

1988 ◽

Vol 156 (1) ◽

pp. 405-411

Author(s):

E. Hadljoudis ◽

I. Mouatakali-maridis ◽

G. Tsoucaris ◽

F. Villain ◽

G. Le Bas

Keyword(s):

Organic Compounds ◽

Inclusion Complexes ◽

Environmental Effects ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion

Download Full-text

Rutin and Its Cyclodextrin Inclusion Complexes: Physico-chemical Evaluation and in vitro Activity on B164A5 Murine Melanoma Cell Line

Current Pharmaceutical Biotechnology ◽

10.2174/1389201019666180209165523 ◽

2018 ◽

Vol 18 (13) ◽

pp. 1067-1077 ◽

Cited By ~ 4

Author(s):

Danciu Corina ◽

Bojin Florina ◽

Pinzaru Iulia ◽

Dehelean Cristina ◽

Ambrus Rita ◽

...

Keyword(s):

Cell Line ◽

Inclusion Complexes ◽

Melanoma Cell Line ◽

In Vitro Activity ◽

Cyclodextrin Inclusion Complexes ◽

Chemical Evaluation ◽

Cyclodextrin Inclusion ◽

Physico Chemical ◽

Murine Melanoma Cell Line

Download Full-text

NMR Internal Standard Signal Shifts Due To Cyclodextrin Inclusion Complexes

Magnetic Resonance in Chemistry ◽

10.1002/mrc.5180 ◽

2021 ◽

Author(s):

Colleen L. Ray ◽

James A. Gawenis ◽

C. Michael Greenlief

Keyword(s):

Inclusion Complexes ◽

Internal Standard ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion ◽

Standard Signal

Download Full-text

Encapsulation of plant extract compounds using cyclodextrin inclusion complexes, liposomes, electrospinning and their combinations for food purposes

Trends in Food Science & Technology ◽

10.1016/j.tifs.2020.12.020 ◽

2021 ◽

Vol 108 ◽

pp. 177-186

Author(s):

Cristina Muñoz-Shugulí ◽

Cristian Patiño Vidal ◽

Plinio Cantero-López ◽

Johana Lopez-Polo

Keyword(s):

Inclusion Complexes ◽

Plant Extract ◽

Cyclodextrin Inclusion Complexes ◽

Cyclodextrin Inclusion

Download Full-text