scholarly journals The ‘how to’ on incentivising farmers to adapt Fusarium mycotoxin management of wheat

2020 ◽  
Author(s):  
Esmée M. Janssen
Keyword(s):  
Fusarium Mycotoxin

scholarly journals 194 Lactulose and hydrogen-rich water protect against fusarium mycotoxin-induced intestinal injury in female piglets.

2018 ◽  
Vol 96 (suppl_3) ◽  
pp. 305-306
Author(s):  
X Ji ◽  
W Zheng ◽  
Q Zhang ◽  
J He ◽  
W Yao
Keyword(s):  
Intestinal Injury ◽  
Fusarium Mycotoxin

scholarly journals Fusarium mycotoxin contamination and co-occurrence in Slovak winter wheat grains

2017 ◽  
Vol 104 (2) ◽  
pp. 173-178 ◽  
Author(s):  
Magdaléna Lacko-Bartošová ◽  
Jaroslav Remža ◽  
Lucia Lacko-Bartošová
Keyword(s):  
Winter Wheat ◽  
Wheat Grains ◽  
Fusarium Mycotoxin ◽  
Mycotoxin Contamination

scholarly journals Incidence of zearalenol (Fusarium mycotoxin) in animal feed.

1979 ◽  
Vol 38 (4) ◽  
pp. 749-750 ◽  
Author(s):  
C J Mirocha ◽  
B Schauerhamer ◽  
C M Christensen ◽  
M L Niku-Paavola ◽  
M Nummi
Keyword(s):  
Animal Feed ◽  
Fusarium Mycotoxin

scholarly journals Expression of a Truncated Form of Ribosomal Protein L3 Confers Resistance to Pokeweed Antiviral Protein and the Fusarium Mycotoxin Deoxynivalenol

2005 ◽  
Vol 18 (8) ◽  
pp. 762-770 ◽  
Author(s):  
Rong Di ◽  
Nilgun E. Tumer
Keyword(s):  
Ribosomal Protein ◽  
Fusarium Species ◽  
Common Mechanism ◽  
Pokeweed Antiviral Protein ◽  
Wild Type ◽  
Antiviral Protein ◽  
Trichothecene Mycotoxin ◽  
Truncated Form ◽  
Fusarium Mycotoxin ◽  
Ribosomal Protein L3

The contamination of important agricultural products such as wheat, barley, or maize with the trichothecene mycotoxin deoxynivalenol (DON) due to infection with Fusarium species is a worldwide problem. Trichothecenes inhibit protein synthesis by targeting ribosomal protein L3. Pokeweed antiviral protein (PAP), a ribosome-inactivating protein binds to L3 to depurinate the α–sarcin/loop of the large rRNA. Plants transformed with the wild-type PAP show lesions and express very low levels of PAP because PAP autoregulates its expression by destabilizing its own mRNA. We show here that transgenic tobacco plants expressing both the wild-type PAP and a truncated form of yeast L3 (L3δ) are phenotypically normal. PAP mRNA and protein levels are very high in these plants, indicating that L3δ suppresses the autoregulation of PAP mRNA expression. Ribosomes are not depurinated in the transgenic plants expressing PAP and L3δ, even though PAP is associated with ribosomes. The expression of the endogenous tobacco ribosomal protein L3 is up-regulated in these plants and they are resistant to the Fusarium mycotoxin DON. These results demonstrate that expression of an N-terminal fragment of yeast L3 leads to trans-dominant resistance to PAP and the trichothecene mycotoxin DON, providing evidence that both toxins target L3 by a common mechanism.

Rainbow trout (Oncorhynchus mykiss) is extremely sensitive to the feed-borne Fusarium mycotoxin deoxynivalenol (DON)

Aquaculture ◽  
2011 ◽  
Vol 311 (1-4) ◽  
pp. 224-232 ◽  
Author(s):  
Jamie M. Hooft ◽  
Abd El Hakeem Ibraheem Elmor ◽  
Pedro Encarnação ◽  
Dominique P. Bureau
Keyword(s):  
Rainbow Trout ◽  
Oncorhynchus Mykiss ◽  
Fusarium Mycotoxin ◽  
Rainbow Trout Oncorhynchus Mykiss

A rapid method for the determination of the Fusarium mycotoxin beauvericin in maize

1999 ◽  
Vol 363 (1) ◽  
pp. 130-131 ◽  
Author(s):  
R. D. Josephs ◽  
R. Krska ◽  
R. Schuhmacher ◽  
M. Grasserbauer
Keyword(s):  
Rapid Method ◽  
Fusarium Mycotoxin

Fast and reproducible chemical synthesis of zearalenone-14-β,D-glucuronide

2012 ◽  
Vol 5 (3) ◽  
pp. 289-296 ◽  
Author(s):  
H. Mikula ◽  
C. Hametner ◽  
F. Berthiller ◽  
B. Warth ◽  
R. Krska ◽  
...  
Keyword(s):  
Chemical Synthesis ◽  
Phase Ii ◽  
Enzymatic Synthesis ◽  
Direct Determination ◽  
Cost Effective ◽  
Reference Substance ◽  
Standard Equipment ◽  
Fusarium Mycotoxin ◽  
Acid Esters

The Fusarium mycotoxin zearalenone (ZEA) is mainly converted to the conjugate zearalenone-14-β,D-glucuronide (ZEA-14-GlcA) during phase II detoxification in humans and animals. This metabolite - previously described as zearalenone-4-O-β,D-glucuronide - is excreted via urine and could therefore serve as possible biomarker for ZEA exposure to estimate its intake. Direct determination of this substance is limited by the availability of a reference substance. So far, only the production of small amounts by enzymatic synthesis has been described. In this work, a fast and reproducible protocol for the chemical synthesis of ZEA-14-GlcA was developed, using substituted β-resorcylic acid esters as mycotoxin mimics and different glucuronyl donors for optimising the glycosylation (Königs-Knorr, trifluoroacetimidate method) and the deprotection step. This cost-effective procedure should be easily reproducible in other labs using standard equipment and common reagents.

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