A rapid method for the determination of the Fusarium mycotoxin beauvericin in maize

1999 ◽  
Vol 363 (1) ◽  
pp. 130-131 ◽  
Author(s):  
R. D. Josephs ◽  
R. Krska ◽  
R. Schuhmacher ◽  
M. Grasserbauer
Keyword(s):  
Rapid Method ◽  
Fusarium Mycotoxin

A Rapid Method for Determination of Buprenorphine and Norbuprenorphine in Urine by UPLC-MS/MS

2020 ◽  
Vol 16 ◽  
Author(s):  
Aykut Kul ◽  
Murat Ozdemir ◽  
Selma Ozilhan ◽  
Olcay Sagirli
Keyword(s):  
Forensic Science ◽  
Rapid Method ◽  
Proficiency Testing ◽  
Mass Spectrometer ◽  
Illicit Market ◽  
Analysis Methods ◽  
Accuracy And Precision ◽  
Lower Limits

Background: Buprenorphine is quite common in the illicit market. Buprenorphine-containing drugs abuse is frequently encountered in patients. The analysis methods used to determine the abuse of buprenorphine and norbuprenorphine are important for forensic science. Buprenorphine is metabolized to norbuprenorphine by the liver. Objective: Therefore, the determination of buprenorphine and norbuprenorphine in urine is one of the methods to determine the abuse of buprenorphine. Methods: In this study, we have developed a precise, simple, and rapid ultra-performance liquid chromatographytandem mass spectrometer method for the determination of buprenorphine and norbuprenorphine simultaneously. Results: The developed method was validated in terms of selectivity and linearity, which was in the range of 9–1800 ng/mL for both buprenorphine and norbuprenorphine. The intra-assay and inter-assay accuracy and precision were found within acceptable limits of the EMA guideline. Lower limits of quantitation were 9 ng/mL for both buprenorphine and norbuprenorphine. Conclusion: The developed method was successfully applied for the determination of both analytes in the proficiency testing samples.

Determination of Dimetridazole and Ipronidazole in Feeds at Cross-Contamination Levels

1988 ◽  
Vol 71 (3) ◽  
pp. 474-477 ◽  
Author(s):  
Duane D Hughes
Keyword(s):  
Thin Layer ◽  
Rapid Method ◽  
Aqueous Phase ◽  
Borate Buffer ◽  
Cross Contamination ◽  
Chromatographic System ◽  
Arsanilic Acid ◽  
Contamination Levels ◽  
Benzene Extract

Abstract A rapid method for the determination of dimetridazole and ipronidazole in feeds is described. The compounds are extracted from a borate buffer (pH 8.65) with benzene, partitioned into IN HC1, and then partitioned back into benzene from a basic aqueous phase. The benzene extract is concentrated and injected onto a nonpolar (Apiezon L) gas chromatographic column for determination by 63Ni electroncapture detection. Recoveries from feeds of various composition, spiked at 0.2 ppm with both dimetridazole and ipronidazole, ranged from 70 to 115%; for the same feeds spiked at 1 ppm or more, the recoveries were greater than 80%. Carbadox, furazolidone, levamisole, oxytetracycline, chlortetracycline, sulfamethazine, sulfaquinoxaline, arsanilic acid, piperazine, penicillin, and commonly added vitamins and minerals do not interfere. A 2-dimensional thin layer chromatographic system is presented as a means of additional identification.

scholarly journals A RAPID METHOD FOR THE DETERMINATION OF CITRIC ACID

1948 ◽  
Vol 175 (2) ◽  
pp. 849-855 ◽  
Author(s):  
Murray. Saffran ◽  
Orville F. Denstedt
Keyword(s):  
Citric Acid ◽  
Rapid Method
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