scholarly journals The experience of the organization of the department of chronic viral infections on the basis of outpatient clinics in a densely populated area of the large megalopolis

2016 ◽  
Vol 21 (6) ◽  
pp. 322-328
Author(s):  
Vitaliy V. Naumenko ◽  
Tamara V. Sologub

The article presents data on the incidence of HIV infection both in the city of St. Petersburg and the Central district of the city of St. Petersburg for the 5-years period. There is given the description of the age and gender of HIV-infected patients. There was performed the analysis of the activity of special unit for care to patients with HIV-infection and chronic viral hepatitis of the Central district of the city of St. Petersburg.

2015 ◽  
Vol 20 (6) ◽  
pp. 15-18
Author(s):  
V. V Naumenko ◽  
T. V Sologub ◽  
V. V Tsvetkov ◽  
L. M Tsybalova

The HIV epidemic has been going on for nearly thirty years, it is a heterogeneous, dynamic and highly resistant to countermeasures. The Leningrad Region and the city of St. Petersburg today are referred to the most affected regions of the Russian Federation, as nearly 1% of the population of this city has HIVpositive status. Despite the decline in the HIV infection incidence of the resident population of the Central District, the epidemiological situation for HIV infection remains to be tense, due to the increase in the cumulative number of HIV-infected and AIDS patients, the increase ofthe morbidity rate and mortality in co-infected patients with HIV/tuberculosis, activation of the output of the epidemic in vulnerable groups into the general population. At the same time, a cohort of HIV-infected patients with a high risk of late detection of tuberculosis continues to form


2004 ◽  
Vol 38 (7) ◽  
pp. 1009-1016 ◽  
Author(s):  
Manuel Ramos‐Casals ◽  
Ricard Cervera ◽  
Mariana Lagrutta ◽  
Francisco Medina ◽  
Mario García‐Carrasco ◽  
...  

2008 ◽  
Vol 205 (12) ◽  
pp. 2699-2701 ◽  
Author(s):  
David A. Hafler ◽  
Vijay Kuchroo

Exhaustion of T cell responses during chronic viral infections has been observed in both mouse and man and has been attributed to up-regulation of PD-1 on the surface of exhausted T cells. In patients with chronic human HIV infection, T cell exhaustion leads to opportunistic infections associated with AIDS. However, not all the exhausted T cells express PD-1, suggesting that other molecules may be involved in the phenotype. A new study now demonstrates a central role for T cell immunoglobulin and mucin domain–containing protein-3 (TIM-3) in T cell exhaustion during chronic HIV infection and suggests that TIM-3 may be a novel therapeutic target in chronic viral diseases.


2020 ◽  
Author(s):  
Aml Ghanem

COVID-19 is a global crisis that requires a deep understanding of infection pathways to facilitate the development of effective treatments and vaccines. Telomere, which is regarded as a biomarker for other respiratory viral infections, might influence the demographic distribution of COVID-19 infection and fatality rates. Viral infection can induce many cellular remodeling events and stress responses, including telomere specific alterations, just as telomere shortening. In brief, this letter aims to highlight the connection between telomere shortening and susceptibility to COVID-19 infection, in addition to changes in telomeric length according to the variation of age and gender of confirmed cases with COVID-19 infection. To sum up, the correlation is revealed from the available data that connect telomere length and COVID-19 infection, demonstrated in the fact that the elderly patients and males are more susceptible to COVID-19 due to shortening in their telomere length.


Author(s):  
R. T. Kamilova ◽  
J. A. Kamilov

Relevance. Characteristics of eruption of secondary teeth is of diagnostic and prognostic interest, is the basis for implementation of targeted therapeutic and preventive measures among children. No research has ever been carried out in Uzbekistan to study an age and gender regional features of secondary teeth eruption. The aim is to determine the timing and symmetry of secondary teeth eruption in children of the city of Tashkent of the Republic of Uzbekistan and comparative assessment with the children of different cities of Russia.Materials and methods. 3,834 children between 3 and 17 years were conducted dental examination. A comparative analysis was made of the initial, intermediate and final periods of eruption of secondary teeth for children of Uzbekistan (Tashkent city) and Russia (Saratov, Izhevsk and Sergach).Results. In Tashkent children of both gender, in most cases, lower teeth were erupted before than their antagonists. In girls, teeth were erupted earlier than their male counterparts. At the initial stage of eruption, asymmetry was more pronounced in boys than in girls, while in the middle and final stages it was more pronounced in the opposite direction. Observed asymmetry of antimere’s teeth were indicated left-handed permanent dentition in boys and right-handed in girls. Children of Tashkent city were observed permanent dentition in one group of teeth 1-16 months earlier, and in others – 1-24 months later than their peers in Russian cities. Revealed differences were more pronounced among boys than among girls. Children in Tashkent differed more from their peers in Sergach and less from those in Izhevsk. Conclusions. Regional peculiarities of permanent dentition in children of Tashkent city and revealed expressed differences with indicators of Russian children are the basis for development of separate age and  gender normative assessment permanent dentition tables for children of Uzbekistan. 


Author(s):  
A. Popov ◽  
O.N. Lopateeva ◽  
A.K. Ovsyankin ◽  
M. M. Satsuk ◽  
A. A. Artyshko ◽  
...  

Among the measures aimed at the effective performance of public services in a modern urban environment, one of the main is the quality control and efficiency of the work performed. Timely street cleaning is hampered by several groups of problems, including the lack of a single automated information system (AIS) control of the work performed. In this regard, there is a need to improve and automate this area. This approach will allow you to combine high performance due to the speed of the system and effective quality control of street cleaning. The purpose of this work is the study and analysis of existing information systems (is), allowing to automate the process of quality control and operational performance of the above tasks. On the basis of the conducted researches, to develop is, having coordinated with the customer (administration of the Central district of Krasnoyarsk) requirements and functionality which allow to automate this process.This article presents the main aspects of the design and software solutions for the implementation of the algorithm in the form of AIS, designed to automate the process of monitoring the cleanliness of streets in the city. The development of AIS was conducted in the PhpStorm integrated development environment in the PHP programming language.


2019 ◽  
Author(s):  
Nicola Coppola ◽  
Caterina Monari ◽  
Loredana Alessio ◽  
Lorenzo Onorato ◽  
Luciano Gualderi ◽  
...  

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