Clinical and epidemiological features of manifestations of Wolf – Parkinson – White syndrome in men of draft age with increased dysplastic stigmatization

2020 ◽  
Vol 22 (3) ◽  
pp. 8-11
Author(s):  
K. S. Shulenin ◽  
D. V. Cherkashin ◽  
G. G. Kutelev ◽  
V. A. Kachnov ◽  
V. S. Ivanov ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Mitral Valve ◽  
Connective Tissue ◽  
Clinical Course ◽  
Lower Number ◽  
White Syndrome ◽  
Epidemiological Features ◽  
Flat Feet ◽  
High Incidence ◽  
Constitution Type

Abstract. Clinical and epidemiological and electrocardiographic features of Wolf Parkinson White syndrome in men of military age were studied. The study was a retrospective study with a solid sample of patients. Of the 1,9056 men residents of St. Petersburg between the ages of 18 and 27, Wolf-Parkinson-White syndrome was identified in 107 (0,56%) people. The disease was asymptomatic in 38 (35,5%) patients. All identified individuals with Wolf Parkinson White syndrome, in addition to asthenic Constitution type, which was observed in 68,2% of cases, were assessed for signs of systemic connective tissue involvement. It was found that flat feet, scoliosis or kyphosis, myopia, as well as mitral valve prolapse and abnormally located chords in the left ventricle of the heart are detected in almost every second man of military age. Due to the inability to assess the presence of all signs of systemic connective tissue involvement, the isolation of specific variants of dysplastic phenotypes in patients with Wolf Parkinson White syndrome was not performed. It was found that in the presence of increased dysplastic stigmatization, the clinical course of Wolf Parkinson White syndrome is characterized by a lower number of asymptomatic cases (6,3 and 16,7%, respectively; p0,05), an increase in the frequency of paroxysmal tachyarrhythmias (81,5 and 63,1%, respectively; p0,05) and a high incidence of vegetative-vascular disorders (82,8 and 15,4%, respectively; p0,05).

scholarly journals Clinico-Epidemiological Features of Melasma : A Retrospective Study from Dermatology-Venereology Department of Education Center Hospital in West Sumatera, Indonesia

2020 ◽  
Vol 13 (4) ◽  
pp. 388-392
Author(s):  
Satya Wydya Yenny
Keyword(s):  
Retrospective Study ◽  
Family History ◽  
Sun Exposure ◽  
Department Of Education ◽  
Symmetric Distribution ◽  
Published Data ◽  
Epidemiological Features ◽  
High Incidence ◽  
Center Hospital ◽  
The Face

Background: Melasma is an acquired, irregularly patterned, light to dark-brown hypermelanosis, with symmetric distribution mostly over the face. Currently there is no published data about incidence of melasma in Indonesia. Methods: Retrospective study was conducted in patients with melasma from January 1, 2016 to December 31, 2018 in Dr. M. Djamil hospital padang, Indonesia. Results: Melasma was more prevalent in females (96.6%) and in Fitzpatrick skin phototypes IV (60 %) and III (40 %). Among 60 patients, centrofacialmelasma was most common (48.3 %), Family history (58.1%) and sun exposure exceeding 1 hour (61.3%) were among the factors contributing to melasma development. The incidences of melasma in 2016-2018 varied every year, the most affected was in female 44-64 years old, the most clinical type is Centrofacial, and epidermal type from Wood’s lamp examination. Conclusions: This population was characterized by: a high incidence in females, Fitzpatrick skin phototypes IV, diseasepresipitation by family history and sun exposure

scholarly journals Tricuspid regurgitation after transcatheter mitral valve repair: Clinical course and impact on outcome

2021 ◽  
Author(s):  
Frank Meijerink ◽  
Karel T. Koch ◽  
Robbert J. Winter ◽  
Daniëlle Robbers‐Visser ◽  
S. Matthijs Boekholdt ◽  
...  
Keyword(s):  
Mitral Valve ◽  
Mitral Valve Repair ◽  
Tricuspid Regurgitation ◽  
Clinical Course ◽  
Valve Repair ◽  
Transcatheter Mitral Valve Repair

Influence of Age on Biochemical Composition of the Mitral Valve Connective Tissue

Gerontology ◽  
1965 ◽  
Vol 11 (3-4) ◽  
pp. 169-178 ◽  
Author(s):  
K. Trnavský ◽  
S. Kopecký ◽  
Z. Trnavská ◽  
L. Cebecauer
Keyword(s):  
Mitral Valve ◽  
Connective Tissue ◽  
Biochemical Composition

Fever of unknown origin in the elderly: nine years experience in China

2008 ◽  
Vol 38 (4) ◽  
pp. 221-222 ◽  
Author(s):  
Minghua Zheng ◽  
Hailong Lin ◽  
Sheng Luo ◽  
Lihua Xu ◽  
Yanjun Zeng ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Connective Tissue ◽  
Connective Tissue Disease ◽  
Older Patients ◽  
Fever Of Unknown Origin ◽  
Unknown Origin ◽  
The Elderly ◽  
Medical College ◽  
Frequent Type ◽  
Wenzhou Medical College

This is a retrospective study of older patients admitted to the First and Second Affiliated Hospitals of Wenzhou Medical College, China, with a diagnosis of fever of unknown origin. The study took place from January 1998 to December 2006 among 102 patients who fulfilled the criteria. Infections were responsible for 50 cases (49.1%), followed by no diagnosis in 27 (26.5%), miscellaneous in nine (8.8%), neoplasms in eight (7.8%) and connective tissue disease in another eight (7.8%). Mycobacterium TB was the most frequent type of infection diagnosed.

scholarly journals CARDIAL MANIFESTATIONS OF NON-DIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA AND THEIR INFLUENCE ON PREGNANCY

2021 ◽  
pp. 14-22
Author(s):  
V. Yu. DOBRIANSKA ◽  
S. M. HERYAK ◽  
L. M. MALANCHUK ◽  
M. I. SHVED ◽  
I. V. KORDA
Keyword(s):  
Mitral Valve ◽  
Connective Tissue ◽  
Ventricular Arrhythmia ◽  
Pregnant Women ◽  
Mitral Valve Prolapse ◽  
Clinical Signs ◽  
Clinical Manifestations ◽  
Adequate Treatment ◽  
Pregnancy And Childbirth ◽  
Connective Tissue Dysplasia

Among the visceral manifestations of NDST in pregnant women most often diagnosed mitral valve prolapse (20-25%) that accompanied by more cardiovascular and obstetric complications during pregnancy. It demonstrates the high clinical significance of the problem of connective tissue dysplasia with mitral valve prolaps for pregnancy and requires adequate treatment programs for prevention of complications and management of pregnant women with connective tissue dysplasia. Aim. Determination of the frequency of pregnancy pathology in women with clinical signs of NDST and MVP complicated by extrasystolic arrhythmia. Materials and methods. 138 pregnant women with MVP and concomitant signs of NDST and 54 healthy pregnant women were selected for analysis. Clinical manifestations of NDST, different variants of arrhythmias and the total number of complications of pregnancy and childbirth were evaluated. Results. In pregnant women with clinical signs of NDST and MVP complicated by extrasystolic arrhythmia, cases of frequent sinus extrasystole were significantly more often compared to frequent ventricular arrhythmia (47.8% vs. 18.1%, p<0.001) and cases of combination of frequent sinus extrasystole and ventricular arrhythmia (13.3 % vs. 1.5%, p <0.05). They significantly more often identified both symptoms of arrhythmological nature and symptoms that indicated a violation of autonomic status. The presence of NDST syndrome is more often accompanied by the development of complications of pregnancy and childbirth. These pregnant women have genetic and phenotypic risk factors for the development of pathological pregnancy and childbirth, birth trauma, disability of mother and newborn, which justifies such patients in a separate risk group for individualized programs of the prevention and treatment of visceral (cardiac) manifestations of NDST and possible complications of pregnancy and childbirth. Conclusions. 3.1% of pregnant women are diagnosed with phenotypic signs (stigma) of undifferentiated connective tissue dysplasia, and the most common visceral cardiac manifestation is mitral valve prolapse. The presence of mitral valve prolapse and extrasystolic arrhythmia in pregnant women with NDST is accompanied by significantly more frequent development of pregnancy and childbirth complications in these patients.

scholarly journals IMMEDIATE RESULTS OF PERCUTANEOUS TRANS-MITRAL COMMISSOROTOMY IN JUVENILE MITRAL STENOSIS

2021 ◽  
Vol 70 (Suppl-4) ◽  
pp. S799-802
Author(s):  
Ahsan Beg ◽  
Muhammad Younas ◽  
Amjad Mahmood ◽  
Mubashar Shervani ◽  
Fakher -e- Fayaz
Keyword(s):  
Retrospective Study ◽  
Mitral Valve ◽  
Transthoracic Echocardiography ◽  
Mitral Stenosis ◽  
Left Atrial ◽  
Left Atrial Size ◽  
Atrial Size ◽  
Mean Pressure ◽  
Long Term Follow Up ◽  
Test Of Significance

Objectives: Immediate result of PTMC in juvenile (5-12 years) rheumatic mitral stenosis. Study Design: Observational descriptive and retrospective study. Place and Duration of Study: Institute of Cardiology, Multan from 2009 to Jun 2020. Methodology: This is an observational descriptive and retrospective study carried out at Institute of Cardiology, Multan from 2009 to Jun 2020. Patients with clinical evidence of significant mitral stenosis were undergone transthoracic echocardiography. Mitral stenosis was defined as mitral valve area <1.0 cm2 . Mean mitral valve gradient was calculated by mitral valve inflow velocities. Patients with Wilkins score <8 were included. Patients with significant MR, left atrial or atrial appendage clot, infective endocarditis, significant aortic regurgitation or any other indication for bypass surgery were excluded. Patients with Wilkins score >8 were also excluded from the study. Variables recorded on a performa were age, weight, left atrial size, mean mitral valve gradient, preprocedure MR. Reduction of mitral valve mean pressure gradients to less than <50% of the initial value was defined as success (without significant or moderate MR). After the procedure, variables recorded on performa were mean left atrial pressures in mmHg (on angio), mean mitral valve gradients and degree of MR (mild, mild to moderate, moderate or severe MR) on transthoracic echocardiography. Paired t-test of significance (p<0.05) was evaluated using SPSS (version 20). Results: Forty three juvenile patients were included the in the study (2009 to June 2019). Mean age was 10.8 ± 1.4 (range 7-12) years. Mean weight was 28.9 ± 5.2 (20-37) kg. Mean mitral valve gradient (on TTE) before the procedure was 20 ± 6 mmHg. Mean left atrial size and mean area of mitral valve were 42 ± 5 mm and 0.8 ± 0.2 cm2 respectively. Balloon sizes used were 26 mm (n=19) and 24 mm (n=24). After PTMC, mean mitral valve reduced to 7 ± 2 mmHg (p<0.005) and left atrial pressure to 18 ± 7 mmHg. Post procedure transthoracic echocardiography showed 4.7% (n=2/43) patients developed moderate to severe or severe MR. So the success rate was 95.3% (n=41/43). Conclusion: PTMC is safe and effective procedure for juvenile patients with mitral stenosis. Long term follow-up is needed to find out period of re-intervention/surgery free duration from the time of PTMC.

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