scholarly journals Clinico-Epidemiological Features of Melasma : A Retrospective Study from Dermatology-Venereology Department of Education Center Hospital in West Sumatera, Indonesia

2020 ◽  
Vol 13 (4) ◽  
pp. 388-392
Author(s):  
Satya Wydya Yenny
Keyword(s):  
Retrospective Study ◽  
Family History ◽  
Sun Exposure ◽  
Department Of Education ◽  
Symmetric Distribution ◽  
Published Data ◽  
Epidemiological Features ◽  
High Incidence ◽  
Center Hospital ◽  
The Face

Background: Melasma is an acquired, irregularly patterned, light to dark-brown hypermelanosis, with symmetric distribution mostly over the face. Currently there is no published data about incidence of melasma in Indonesia. Methods: Retrospective study was conducted in patients with melasma from January 1, 2016 to December 31, 2018 in Dr. M. Djamil hospital padang, Indonesia. Results: Melasma was more prevalent in females (96.6%) and in Fitzpatrick skin phototypes IV (60 %) and III (40 %). Among 60 patients, centrofacialmelasma was most common (48.3 %), Family history (58.1%) and sun exposure exceeding 1 hour (61.3%) were among the factors contributing to melasma development. The incidences of melasma in 2016-2018 varied every year, the most affected was in female 44-64 years old, the most clinical type is Centrofacial, and epidermal type from Wood’s lamp examination. Conclusions: This population was characterized by: a high incidence in females, Fitzpatrick skin phototypes IV, diseasepresipitation by family history and sun exposure

Clinical and epidemiological features of manifestations of Wolf – Parkinson – White syndrome in men of draft age with increased dysplastic stigmatization

2020 ◽  
Vol 22 (3) ◽  
pp. 8-11
Author(s):  
K. S. Shulenin ◽  
D. V. Cherkashin ◽  
G. G. Kutelev ◽  
V. A. Kachnov ◽  
V. S. Ivanov ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Mitral Valve ◽  
Connective Tissue ◽  
Clinical Course ◽  
Lower Number ◽  
White Syndrome ◽  
Epidemiological Features ◽  
Flat Feet ◽  
High Incidence ◽  
Constitution Type

Abstract. Clinical and epidemiological and electrocardiographic features of Wolf Parkinson White syndrome in men of military age were studied. The study was a retrospective study with a solid sample of patients. Of the 1,9056 men residents of St. Petersburg between the ages of 18 and 27, Wolf-Parkinson-White syndrome was identified in 107 (0,56%) people. The disease was asymptomatic in 38 (35,5%) patients. All identified individuals with Wolf Parkinson White syndrome, in addition to asthenic Constitution type, which was observed in 68,2% of cases, were assessed for signs of systemic connective tissue involvement. It was found that flat feet, scoliosis or kyphosis, myopia, as well as mitral valve prolapse and abnormally located chords in the left ventricle of the heart are detected in almost every second man of military age. Due to the inability to assess the presence of all signs of systemic connective tissue involvement, the isolation of specific variants of dysplastic phenotypes in patients with Wolf Parkinson White syndrome was not performed. It was found that in the presence of increased dysplastic stigmatization, the clinical course of Wolf Parkinson White syndrome is characterized by a lower number of asymptomatic cases (6,3 and 16,7%, respectively; p0,05), an increase in the frequency of paroxysmal tachyarrhythmias (81,5 and 63,1%, respectively; p0,05) and a high incidence of vegetative-vascular disorders (82,8 and 15,4%, respectively; p0,05).

scholarly journals A Scenario of Cervical Carcinoma in a Cancer Hospital

2009 ◽  
Vol 48 (175) ◽  
Author(s):  
Anjani Kumar Jha ◽  
Jyoti Jha ◽  
Rabin Bista ◽  
B Basnet ◽  
Prakash Kandel ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Squamous Cell Carcinoma ◽  
Retrospective Study ◽  
Family History ◽  
Early Detection ◽  
Cervical Carcinoma ◽  
Positive Family History ◽  
Published Data ◽  
Maximum Frequency ◽  
Cancer Pattern

Introduction: Cervical carcinoma is an important women’s health problem throughout the world.There are very few published data on this disease in Nepal. We wanted to study the pattern ofcervical carcinoma based on hospital data.Methods: A 10 years retrospective study of scenario of cervical carcinoma was conducted. The datahave been analyzed according to age, occurrence of other cancers, histological type, religion, riskfactors and district wise.Results: The number of cervical carcinoma showed a rising pattern over the 10 year period. Themedian age of the patients was 45 years and maximum frequency (33%) of cases were found in theage group 40 to 49 years. Squamous cell carcinoma comprised 40% of cases, Adenocarcinoma 4% and1.1% cases were of mixed variety. 92% of cases were Hindu by religion. 43% of patients were smokerin our study, 5% had positive family history. Chitwan with 7.35% had the maximum number of casesfollowed by Rupandehi with 6.40% and Nawalparasi with 5.41%.Conclusions: The cancer pattern revealed by the present study provides valuable leads to cervicalcancer epidemiology in Nepal. Routine cytological screening of the population for cervical cancer ishighly necessary for its early detection and treatment.Key Words: Cervical carcinoma, hospital based study, Nepal, pattern

MELASMA: A HOSPITAL BASED RETROSPECTIVE STUDY ON CLINICOEPIDEMIOLOGICAL PROFILE

2021 ◽  
pp. 23-25
Author(s):  
Tanya Pandey ◽  
Pranjal Ahire ◽  
Shylaja Someshwar
Keyword(s):  
Retrospective Study ◽  
Family History ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Age At Onset ◽  
Sun Exposure ◽  
Care Hospital ◽  
Exposed Skin ◽  
Female Predominance ◽  
Using Data

Background: Melasma is a common, therapeutically challenging, psychological distressing, pigmentary disorder of sun exposed skin. Aim Of The Study: To study the clinical and epidemiological prole of melasma patients. Materials And Methods: Tertiary care hospital retrospective study using data of melasma patients who attended the dermatology outpatient clinic between February 2012 to May 2021. Study included 296 patients above 18 years. Demographic details were obtained from the pigment clinic proforma. Results: Mean age of 296 patients was 35.4 years, with female predominance (86.1%). Mean age at onset of melasma was 31.9 years. Aggravation with sun exposure was noted in 64.2% cases. Family history was present in 15.2% cases while hypothyroidism in 3.4% cases. Malar involvement was commonest (68.6%). Under Wood's lamp, epidermal type was commonest (57.4%). Cosmetic usage was present in 6.4% cases. Pregnancy precipitation and pregnancy aggravation was noted in 16.5% and 9% females. 7.5% females reported OC pill usage. Conclusion:This study showcases the multifaceted prole of patients aficted with melasma in a tertiary care hospital.

Sex (Similarities and) Differences in Friendship Jealousy

2020 ◽  
Author(s):  
Jaimie Krems ◽  
Keelah Williams ◽  
Laureon Allison Watson ◽  
Douglas Kenrick ◽  
Athena Aktipis
Keyword(s):  
Sex Differences ◽  
Cognitive Architecture ◽  
Third Party ◽  
Published Data ◽  
Best Friends ◽  
Adaptive Challenges ◽  
The Face ◽  
Initial Support ◽  
Fitness Benefits ◽  
Material Benefits

Friendships provide material benefits, bolster health, and may help solve adaptive challenges. However, a recurrent obstacle to sustaining those friendships—and thus enjoying many friendship-mediated fitness benefits—is interference from other people. Friendship jealousy may be well-designed for helping both men and women meet the recurrent, adaptive challenge of retaining friends in the face of such third-party interference. Although we thus expect several sex similarities in the general cognitive architecture of friendship jealousy (e.g., it is attuned to friend value), there are also sex differences in friendship structures and historical functions, which might influence the inputs of friendship jealousy (e.g., the value of any one friendship). If so, we should also expect some sex differences in friendship jealousy. Findings from a reanalysis of previously-published data and a new experiment, including both U.S. student and adult community participants (N = 993), provide initial support for three predicted sex differences: women (versus men) report greater friendship jealousy at the prospective loss of best friends to others, men (versus women) report greater friendship jealousy at the prospective loss of acquaintances to others, and men’s (but not women’s) friendship jealousy is enhanced in the context of intergroup contests.

Gallbladder Paraganglioma: A Case Report With Review of the Literature

2005 ◽  
Vol 129 (4) ◽  
pp. 523-526 ◽  
Author(s):  
Shveta Mehra ◽  
Moonja Chung-Park
Keyword(s):  
Case Report ◽  
Retrospective Study ◽  
Family History ◽  
Gastrointestinal Bleeding ◽  
Biliary System ◽  
Rare Tumor ◽  
Review Of The Literature ◽  
Quadrant Pain ◽  
Endocrine Neoplasia ◽  
History Of

Abstract We report a case of gallbladder paraganglioma that was discovered during nonrelated surgery. Retrospective study disclosed a family history of pheochromocytoma. The occurrence of gallbladder paraganglioma in the presence of family history of endocrine neoplasia supports that gallbladder paraganglioma may indeed occur as a part of the multiple endocrine neoplasm syndrome. Gallbladder paraganglioma is a rare tumor, and so far to our knowledge only 6 cases have been reported in the literature. Three cases were discovered incidentally during cholecystectomy for cholelithiasis, 2 presented with right upper quadrant pain, and 1 manifested with gastrointestinal bleeding. We herein review all reported cases of paraganglioma of gallbladder and biliary system.

Molecular Screening for Hereditary Nonpolyposis Colorectal Cancer: A Prospective, Population-Based Study

2001 ◽  
Vol 19 (19) ◽  
pp. 3944-3950 ◽  
Author(s):  
Antonio Percesepe ◽  
Francesca Borghi ◽  
Mirco Menigatti ◽  
Lorena Losi ◽  
Moira Foroni ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Family History ◽  
Germline Mutation ◽  
Hereditary Nonpolyposis Colorectal Cancer ◽  
Germline Mutations ◽  
Screening Programs ◽  
High Incidence ◽  
Hereditary Nonpolyposis ◽  
Incident Cases ◽  
High Incidence Area

PURPOSE: Germline mutations in mismatch repair genes predispose to hereditary nonpolyposis colorectal cancer (HNPCC). To address effective screening programs, the true incidence of the disease must be known. Previous clinical investigations reported estimates ranging between 0.5% and 13% of all the colorectal cancer (CRC) cases, whereas biomolecular studies in Finland found an incidence of 2% to 2.7% of mutation carriers for the disease. The aim of the present report is to establish the frequency of the disease in a high-incidence area for colon cancer. PATIENTS AND METHODS: Through the data of the local CRC registry, we prospectively collected all cases of CRC from January 1, 1996, through December 31, 1997 (N = 391). Three hundred thirty-six CRC cases (85.9% of the incident cases) were screened for microsatellite instability (MSI) with six to 12 mono- and dinucleotide markers. MSI cases were subjected to MSH2 and MLH1 germline mutation analysis and immunohistochemistry; the methylation of the promoter region was studied for MLH1. RESULTS: Twenty-eight cases (8.3% of the total) showed MSI. MSI cases differed significantly from microsatellite-stable (MSS) cases for their proximal location (P < .01), high mucinous component (P < .01), and poor differentiation (P = .002). Of MSI cases studied (n = 12), only one with a family history compatible with HNPCC had a germline mutation (in MSH2). Five other patients with a family history of HNPCC (two with MSI and three with MSS tumors) did not show germline mutations. CONCLUSION: We conclude that the incidence of molecularly confirmed HNPCC (one [0.3%] of 336) in a high-incidence area for CRC is lower than in previous biomolecular and clinical estimates.

scholarly journals Steroid-induced Rosacea- A Study From a Tertiary Care Hospital of Eastern Nepal

2021 ◽  
Vol 19 (1) ◽  
pp. 25-29
Author(s):  
Manoj Chaudhary ◽  
Sudha Agrawal
Keyword(s):  
Tertiary Care ◽  
Age Groups ◽  
Case Series ◽  
Sun Exposure ◽  
Care Hospital ◽  
Facial Erythema ◽  
Case Series Study ◽  
The Face ◽  
Triggering Factor ◽  
Study Population

Introduction: Topical corticosteroids (TC) are useful for treatment of various dermatological conditions in all age groups. Due to its cosmetic application TCs misuse is intertwined with fairness creams in our colour conscious society where people are obsessed with fair colour.   Aims and Objectives: To find the clinical presentations of steroid induced rosacea like-dermatitis on the face and to evaluate the purpose behind misusing TCs on the face.   Materials and methods: Descriptive prospective questionnaire-type case series study was approved by Institutional Ethical Committee of BPKIHS which involved 205 patients diagnosed as Steroid Induced Rosacea who consulted Dermatology OPD between March to June 2017.   Results: Among 205 patients enrolled, majority were from second to fourth decade (87.31%) of their life and maximum being females I.e. 91.2%. Around 97% of the study population were unaware of side effects of TCs. Most patients use Mometasone fuorate (58.04%) for melisma (88.29%). Friends acted as source of prescription (29.75%), followed by Pharmacist (24.88%) & Beauty centers (20%). Dermatologists prescribed TCs in only 6.34% cases. Sun exposure was identified as the triggering factor for steroid induced rosacea in 73.17% patients. Cheek was the commonest site involve in 92.19%, followed by forehead (65.36%), perioral area (46.83%), and chin (9.75%). Mixed type of lesions was the commonest lesion found in 52.20% patients, followed by diffuse facial erythema (36.09%), & telangiectasia (33.17%).   Conclusion: TCs misuse in the younger people for the sake of fairer skin with little or no knowledge about the adverse effects of this medication should be stopped.

scholarly journals Lip Shaving in Carcinoma Lower Lip and Reconstruction by Local Advancement Mucosal Flap Under Local Anesthesia: A Case Report

2020 ◽  
Vol 5 (8) ◽  
pp. 905-909
Author(s):  
Tareq Mohammed ◽  
Mamoon TB ◽  
Md Sirajul Islam ◽  
Md Aminul Islam ◽  
Farid Uddin Milki ◽  
...  
Keyword(s):  
Sun Exposure ◽  
Squamous Cell Carcinomas ◽  
Careful Planning ◽  
Lower Lip ◽  
Verbal Expression ◽  
Lip Reconstruction ◽  
Mucosal Flap ◽  
The Face ◽  
Extensive Surgery ◽  
Oral Commissure

The lips are one of the most important features of the face; and are functionally and aesthetically very important. It serves as border of the oral commissure, provides access to oral cavity and contributes to oral competence. It is important for verbal expression and fundamental for facial expression and overall appearance of face1 . Excessive sun exposure and tobacco use, may develop cancer. The cancer can occur anywhere along the upper or lower lip, but is most common on the lower lip. Most lip cancers are squamous cell carcinomas. Surgery is the main stay of treatment and lip shave is an established modality for superficial lesion followed by reconstruction. Extensive surgery may be necessary for larger lesion. Careful planning and reconstruction can restore eating and speaking normally, and also achieve a satisfactory appearance after surgery. Evidence supports that the concept of lip reconstruction started as early as 1000 BC in the sacred texts of great Susruta, India2 . Lip mucosa is very special and it is recommended to reconstruct the surgical defect with lip tissue whenever possible, as any other tissue is never comparable or can replace the lip tissue3 . This is the example of this presented case.

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