scholarly journals Biological Dosimetry Using Micronucleus Assay in Simulated Partial-Body Exposure to Ionizing Radiation

2017 ◽  
Vol 43 (2) ◽  
pp. 75 ◽  
Author(s):  
S. Purnami ◽  
S. Nurhayati ◽  
M. Syaifudin ◽  
D. Ramadhani
Keyword(s):  
Ionizing Radiation ◽  
Micronucleus Assay ◽  
Biological Dosimetry ◽  
Partial Body

scholarly journals Use of Biological Dosimetry for Monitoring Medical Workers Occupationally Exposed to Ionizing Radiation

Radiation ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 95-115
Author(s):  
Igor Piotrowski ◽  
Aleksandra Dawid ◽  
Katarzyna Kulcenty ◽  
Wiktoria Maria Suchorska
Keyword(s):  
Ionizing Radiation ◽  
Low Dose ◽  
Micronucleus Assay ◽  
Occupational Exposures ◽  
Peripheral Blood Lymphocytes ◽  
Genotoxic Effects ◽  
Protection Measures ◽  
Physical Methods ◽  
Biological Dosimetry ◽  
Occupationally Exposed

Medical workers are the largest group exposed to man-made sources of ionizing radiation. The annual doses received by medical workers have decreased over the last several decades, however for some applications, like fluoroscopically guided procedures, the occupational doses still remain relatively high. Studies show that for some procedures the operator and staff still use insufficient protective and dosimetric equipment, which might cause an underestimation of medical exposures. Physical dosimetry methods are a staple for estimating occupational exposures, although due to the inconsistent use of protection measures, an alternative method such as biological dosimetry might complement the physical methods to achieve a more complete picture. Such methods were used to detect exposures to doses as low as 0.1 mSv/year, and could be useful for a more accurate assessment of genotoxic effects of ionizing radiation in medical workers. Biological dosimetry is usually based on the measurement of the effects present in peripheral blood lymphocytes. Although some methods, such as chromosome aberration scoring or micronucleus assay, show promising results, currently there is no one method recognized as most suitable for dosimetric application in the case of chronic, low-dose exposures. In this review we decided to evaluate different methods used for biological dosimetry in assessment of occupational exposures of medical workers.

The Persistence of FISH Translocations for Retrospective Biological Dosimetry after Simulated Whole or Partial Body Irradiation

1998 ◽  
Vol 76 (3) ◽  
pp. 159-168 ◽  
Author(s):  
Y.C. Guerrero-Carbajal ◽  
J.E. Moquet ◽  
A.A. Edwards ◽  
D.C. Lloyd
Keyword(s):  
Biological Dosimetry ◽  
Partial Body

The micronucleus assay as a biological dosimeter in hospital workers exposed to low doses of ionizing radiation

2012 ◽  
Vol 747 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Monica Ropolo ◽  
Cristina Balia ◽  
Paola Roggieri ◽  
Vittorio Lodi ◽  
Maria Concetta Nucci ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Micronucleus Assay ◽  
Low Doses ◽  
Hospital Workers

Detection of Partial-Body Exposure to Ionizing Radiation by the Automatic Detection of Dicentrics

2012 ◽  
Vol 178 (4) ◽  
pp. 357-364 ◽  
Author(s):  
Aurelie Vaurijoux ◽  
Eric Gregoire ◽  
Sandrine Roch-Lefevre ◽  
Pascale Voisin ◽  
Cecile Martin ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Automatic Detection ◽  
Partial Body

scholarly journals New approaches to biological dosimetry: development of complex biodosimetric systems (review of foreign literature)

2019 ◽  
pp. 90-96
Author(s):  
N. V. Sotnik ◽  
V. L. Rybkina ◽  
T. V. Azizova
Keyword(s):  
Radiation Dose ◽  
Ionizing Radiation ◽  
Biological Markers ◽  
Large Scale ◽  
Accurate Estimate ◽  
Dose Assessment ◽  
Radiation Doses ◽  
Biological Dosimetry ◽  
Radiation Accidents ◽  
Combined Use

Relevance. In case of emergency due to large-scale radiation accidents, biological dosimetry becomes a critical tool for early radiation dose assessment and enables identification of individuals exposed to ionizing radiation and facilitates further medical follow-up decisions.Intention. To assess the feasibility of a number of biological markers for bioindication and biodosimetry purposes based on literature data.Methodology. Literature sources were searched in MEDLINE databases, PubMed, CyberLeninka, elibrary.ru, using the terms: radiation, irradiation, biodosimetry. The review presents the results of studies from full-text sources of literature in English.Results and Discussion. Depending on an accidental exposure scenario, various biodosimetry techniques should be used to assess radiation doses with optimal accuracy and speed. In addition to physical methods and clinical techniques used to assess radiation doses, biological dosimetry defines a level of ionizing radiation exposure for certain individuals and is useful in making decisions about medical treatment strategy. To date, combined use of several biological markers within a biodosimetry system providing reliable radiation dose estimates.Conclusion. Analysis of the data presented in the review showed that combined use of several biological markers and development of a complex biodosimetric system will provide a more accurate estimate of doses, which is especially important in case of radiation accidents and incidents when physical dosimetry data are not available.

scholarly journals Estimating partial-body ionizing radiation exposure by automated cytogenetic biodosimetry

2020 ◽  
Vol 96 (11) ◽  
pp. 1492-1503
Author(s):  
Ben C. Shirley ◽  
Joan H. M. Knoll ◽  
Jayne Moquet ◽  
Elizabeth Ainsbury ◽  
Ngoc-Duy Pham ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
Radiation Exposure ◽  
Partial Body ◽  
Ionizing Radiation Exposure
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