Effects of Particle Sizes and Natural Polymers on Mechanical Properties of Alpha Tricalcium Phosphate Cements

MRS Advances ◽  
2016 ◽  
Vol 1 (18) ◽  
pp. 1277-1282
Author(s):  
Shota Ishii ◽  
Tomoaki Sugiyama ◽  
Jeffrey S. Cross ◽  
Toshiyuki Ikoma
Keyword(s):  
Mechanical Properties ◽  
Tricalcium Phosphate ◽  
Particle Sizes ◽  
Dicalcium Phosphate Dihydrate ◽  
Natural Polymers ◽  
Cold Isostatic Press ◽  
Spray Dry ◽  
Calcium Phosphate Cements ◽  
Phosphate Dihydrate ◽  
Tilapia Scale

ABSTRACTCalcium phosphate cements show self-hardening reaction upon mixing with liquids to form calcium-deficient hydroxyapatite (CDHA) or dicalcium phosphate dihydrate. The effects of particle sizes, crystallinities, and natural polymers such as tilapia scale collagen (Col) and hyaluronic acid as a dispersant on the mechanical properties of alpha tricalcium phosphate (TCP) cements mixed with citric acid (CA) as an additive were investigated. Three types of alpha TCP particles were fabricated with spray-dry (SD; 14 μm), freeze-dry (FD; 45 μm), and cold isostatic press (CIP; 134 μm) methods, followed by sintering at 1300°C and ground/crushed. The amounts of Ca dissolution from these particles were in the order of SD > FD > CIP. The CA liquid was added to the powders of SD-FD or SD-CIP, and kneaded under different liquid/powder ratios. The cements containing CIP particles showed lower compressive strength at 22.9 ± 1.5 MPa than those containing FD particles at 28.3 ± 2.5 MPa, even though the apparent densities of the cements containing CIP material was higher. Although the packing density of powders is an important factor on the mechanical properties of cements, the dissolution of Ca ion has a greater impact on the mechanical properties. The addition of Col into the cements increased the mechanical properties at 33.6 ± 2.5 MPa at 1 day to enhance the re-precipitation of CDHA.

Synthesis of Alpha-Tricalcium Phosphate by Wet Reaction and Evaluation of Mechanical Properties

2012 ◽  
Vol 727-728 ◽  
pp. 1164-1169 ◽  
Author(s):  
Mônica Beatriz Thürmer ◽  
Rafaela Silveira Vieira ◽  
Juliana Machado Fernandes ◽  
Wilbur Trajano Guerin Coelho ◽  
Luis Alberto Santos
Keyword(s):  
Mechanical Properties ◽  
Calcium Phosphate ◽  
Tricalcium Phosphate ◽  
Calcium Nitrate ◽  
Chemical Precipitation ◽  
Particle Size Analysis ◽  
Size Analysis ◽  
X Ray Diffraction ◽  
X Ray ◽  
Calcium Phosphate Cements

Calcium phosphate cements have bioactivity and osteoconductivity and can be molded and replace portions of bone tissue. The aim of this work was to study the obtainment of α-tricalcium phosphate, the main phase of calcium phosphate cement, by wet reaction from calcium nitrate and phosphoric acid. There are no reports about α-tricalcium phosphate obtained by this method. Two routes of chemical precipitation were evaluated and the use of two calcinations temperatures to obtain the phase of cement. The influence of calcination temperature on the mechanical properties of cement was evaluated. Cement samples were characterized by particle size analysis, X-ray diffraction, mechanical strength and scanning electron microscopy. The results demonstrate the strong influence of synthesis route on the crystalline phases of cement and the influence of concentration of reactants on the product of the reaction, as well as, on the mechanical properties of cement.

Fully-Interconnected Pore Forming Calcium Phosphate Cement

2011 ◽  
Vol 493-494 ◽  
pp. 832-835 ◽  
Author(s):  
Ishikawa Kunio ◽  
Kanji Tsuru ◽  
Trung Kien Pham ◽  
Michito Maruta ◽  
Shigeki Matsuya
Keyword(s):  
Calcium Phosphate ◽  
Porous Structure ◽  
Calcium Phosphate Cement ◽  
Tricalcium Phosphate ◽  
Porous Body ◽  
Phosphate Solution ◽  
Dicalcium Phosphate Dihydrate ◽  
Phosphate Dihydrate ◽  
Bone Defect Reconstruction ◽  
Interconnected Pore

Calcium phosphate cement that foams fully-interconnected porous structure along with its gradual replacement to bone may be ideal for bone defect reconstruction. In the present study, α-tricalcium phosphate (αTCP) microspheres were exposed to acidic calcium phosphate solution. It was found that the αTCP microspheres set in approximately 10 min to form fully-interconnected porous structure. The porosity was approximately 50% and the pore size was 300µm. The surface of the porous body was dicalcium phosphate dihydrate whereas the inside was αTCP.

Fabrication of βTCP with Fully-Interconnected Porous Structure

2011 ◽  
Vol 493-494 ◽  
pp. 135-138
Author(s):  
Taro Nikaido ◽  
Kanji Tsuru ◽  
Fumikazu Daitou ◽  
Melvin L. Munar ◽  
Shigeki Matsuya ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Porous Structure ◽  
Tricalcium Phosphate ◽  
Single Phase ◽  
Sintering Temperature ◽  
Crystal Phase ◽  
Dicalcium Phosphate Dihydrate ◽  
Bone Filler ◽  
Phosphate Dihydrate ◽  
Significant Difference

Calcium phosphate foam could be an ideal bone filler and scaffold for tissue engineering. This paper describes fabrication method of β-tricalcium phosphate (βTCP) foam with fully-interconnected porous structure by employing magnesium oxide (MgO) as βTCP stabilizer. The foam was prepared using the so-called ceramics foam method. MgO was added to calcium carbonate and dicalcium phosphate dihydrate so that 0, 1, 2, 3, 4, 6 and 8 mol% calcium would be substituted by magnesium (Mg) in βTCP structure. After sintering at 1500°C, crystal phase of the obtained foam included α-tricalcium phosphate (αTCP) when no Mgor less than 3 mol% Mg was added. In contrast, crystal phase was single phase βTCP when 3 mol% or higher Mg was added. The compressive strength was approximately 15 kPa and the porosity was above 95% for all specimens. No significant difference was observed between αTCP and βTCP foams in compressive strength and porosity when the sintering temperature was the same.

Analysis on the Setting of Brushite Bone Cement after Storage in the Humid Environment

2016 ◽  
Vol 696 ◽  
pp. 32-35
Author(s):  
Tai Joo Chung ◽  
Kyung Sik Oh
Keyword(s):  
Bone Cement ◽  
Tricalcium Phosphate ◽  
Driving Force ◽  
Activation Barrier ◽  
Setting Time ◽  
Dicalcium Phosphate ◽  
Dicalcium Phosphate Dihydrate ◽  
Major Phase ◽  
Phosphate Dihydrate ◽  
Humid Environment

The cause of the degradation was analyzed by applying the highly humid conditions during the storage of cement composed of β-tricalcium phosphate (β-TCP) and monocalcium phosphate monohydrate (MCPM). For the β-TCP and MCPM stored separately under the humid environment, the mild increase in the setting time was observed, and the product after the setting was entirely dicalcium phosphate dihydrate (CaHPO42H2O: DCPD). However, for the β-TCP and MCPM stored mixed under the same condition, the setting time significantly increased with the period of storage, and the product contained dicalcium phosphate (CaHPO4: DCP) as major phase, resulting in the loss of setting ability. The formation of DCP could be because of the weak driving force for setting, caused by a feeble supply of water from moisture. As the formation of DCPD requires stronger driving force to overcome the activation barrier, sufficient amount of water is essential. Humid environment during the storage decreased the driving force by the formation of DCP, and the driving force to produce DCPD was lost during the actual setting.

Effect of Different Granular Size on the Properties of Porous β-Tricalcium Phosphate Foam Granular Cements

2019 ◽  
Vol 829 ◽  
pp. 23-27 ◽  
Author(s):  
Haifaa' Auni Mohammad Zaki ◽  
Khairul Anuar Shariff ◽  
Mohamad Hafizi Abu Bakar ◽  
Mohamad Nurul Azmi
Keyword(s):  
Calcium Phosphate ◽  
Tricalcium Phosphate ◽  
Reaction Times ◽  
Range Size ◽  
Dicalcium Phosphate ◽  
Morphological Observation ◽  
Phosphate Solution ◽  
Dicalcium Phosphate Dihydrate ◽  
Setting Reaction ◽  
Phosphate Dihydrate

Porous β-tricalcium phosphate (β-TCP) foam granular cements was obtained by exposing different range size of β-TCP foam granular (300-600 μm and 600-1000 μm) with 1.4 mol/L of saturated acidic calcium phosphate solution at various setting reaction times. It was found that large amount of dicalcium phosphate dihydrate (DCPD) was formed in the set specimens after exposing small size of β-TCP foam granular with saturated acidic calcium phosphate solution. Morphological observation shows that the bridging of DCPD platelet-like crystals between β-TCP foam granular surfaces were detected as early as 10 mins after exposing 300-600 μm of β-TCP foam granules with saturated acidic calcium phosphate solution. In fact, the amount of DCPD formed in the specimens obtained from small size of β-TCP foam granules is higher than large sized foam granules. These results demonstrated that small size of β-TCP foam granules induced fast setting reaction of β-TCP foam granules to produce porous β-TCP foam granular cements.

Seeded Growth of Calcium Phosphates: Effect of Different Calcium Phosphate Seed Material

1976 ◽  
Vol 55 (4) ◽  
pp. 617-624 ◽  
Author(s):  
G.H. Nancollas ◽  
J.S. Wefel
Keyword(s):  
Calcium Phosphate ◽  
Tricalcium Phosphate ◽  
Calcium Phosphates ◽  
Octacalcium Phosphate ◽  
Dicalcium Phosphate ◽  
Dicalcium Phosphate Dihydrate ◽  
Seeded Growth ◽  
Seed Crystals ◽  
Phosphate Dihydrate ◽  
Supersaturated Solutions

The growth of calcium phosphates on seed materials, dicalcium PhosPhate dihydrate (DCPD), tricalcium phosphate (TCP), octacalcium phosphate (OCP), and hydroxyapatite (HAP) in stable supersaturated solutions has been studied under conditions of pH and concentration for which the predominant phases are 1, DCPD, and II, HAP. All seed crystals are good nucleators for DCPD in system I, but, aside from HAP itself, only OCP will readily induce growth under condition II.

Effects of particle sizes, wood to cement ratio and chemical additives on the properties of sesendok (Endospermum Diadenum) cement-bonded particleboard

2010 ◽  
Vol 7 (2) ◽  
pp. 57
Author(s):  
Jamaludin Kasim ◽  
Shaikh Abdul Karim Yamani ◽  
Ahmad Firdaus Mat Hedzir ◽  
Ahmad Syafiq Badrul Hisham ◽  
Mohd Arif Fikri Mohamad Adnan
Keyword(s):  
Mechanical Properties ◽  
Experimental Investigation ◽  
Cement Content ◽  
Particle Sizes ◽  
Thickness Swelling ◽  
Chemical Additives ◽  
Board Density ◽  
Cement Ratio ◽  
Aluminium Silicate ◽  
Cement Board

An experimental investigation was performed to evaluate the properties of cement-bonded particleboard made from Sesendok wood. The target board density was set at a standard 1200 kg m". The effect offarticle size, wood to cement ratio and the addition ofsodium silicate and aluminium silicate on the wood cement board properties has been evaluated. A change ofparticle size from 1.0 mm to 2.0 mm has a significant effect on the mechanical properties, however the physical properties deteriorate. Increasing the wood to cement ratio from 1:2.25 to 1:3 decreases the modulus ofrupture (MOR) by 11% and the addition ofsodium silicate improves valuesfurther by about 28% compared to the addition ofaluminum silicate. The modulus ofelasticity (MOE) in general increases with increasing cement content, but is not significantly affected by the addition ofsodium silicate or aluminium silicate, although the addition of their mixture (sodium silicate andaluminium silicate) consistentlyyields greater MOE values. Water absorption and thickness swelling is significantly affected by the inclusion ofadditives and better values are attained using higher wood to cement ratios.

The Sintering Behaviour and Mechanical Properties of Hydroxyapatite - Based Composites for Bone Tissue Regeneration

2018 ◽  
Vol 69 (5) ◽  
pp. 1272-1275 ◽  
Author(s):  
Camelia Tecu ◽  
Aurora Antoniac ◽  
Gultekin Goller ◽  
Mustafa Guven Gok ◽  
Marius Manole ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Tricalcium Phosphate ◽  
Cosmetic Surgery ◽  
Mechanical Stability ◽  
Raw Materials ◽  
Oyster Shell ◽  
Bone Tissue Regeneration ◽  
Sintering Behavior ◽  
Bovine Bone ◽  
Human Teeth

Bone reconstruction is a complex process which involves an osteoconductive matrix, osteoinductive signaling, osteogenic cells, vascularization and mechanical stability. Lately, to improve the healing of the bone defects and to accelerate the bone fusion and bone augmentation, bioceramic composite materials have been used as bone substitutes in the field of orthopedics and dentistry, as well as in cosmetic surgery. Of all types of bioceramics, the most used is hydroxyapatite, because of its similar properties to those of the human bone and better mechanical properties compared to b-tricalcium phosphate [1]. Currently, the most used raw materials sources for obtaining the hydroxyapatite are: bovine bone, seashells, corals, oyster shell, eggshells and human teeth. There are two common ways to obtain hydroxyapatite: synthetically and naturally. Generally, for the improvement of the mechanical properties and the structural one, hydroxyapatite is subjected to the sintering process. Considering the disadvantages of hydroxyapatite such as poor biodegradation rate, b-TCP has been developed, which has some disadvantages too, such as brittleness. For this reason, the aim of this study is to look into the effect of adding magnesium oxide on the sintering behavior, the structure and the mechanical properties of the hydroxyapatite-tricalcium phosphate composites.

Sign in / Sign up

Export Citation Format

Share Document