scholarly journals Oestrus synchronisation in postpartum dairy cows using repetitive prostaglandin doses: Comparison between D-cloprostenol and dinoprost

2015 ◽  
Vol 63 (1) ◽  
pp. 79-88
Author(s):  
Carlos Pérez-Marín ◽  
Jose Sánchez ◽  
Guillermo Vizuete ◽  
Luis Quintela ◽  
Laura Molina

This trial evaluated the reproductive performance in an early routine oestrus induction programme using two different PGF2α preparations in dairy cattle. D-cloprostenol sodium (n = 192; Group A) or dinoprost (n = 187; Group B) was administered between days 35 and 42 post partum. Also, a group of non-treated cows (n = 135; Group C) was included as control. Pedometers were used to detect oestrus, and also secondary oestrous signs and vaginal mucus quality were assessed prior to artificial insemination (AI). When oestrus was not detected for 14 days after PGF2α administration, the treatment was repeated, up to a maximum of three times. There were no differences between the study groups in oestrus detection (A = 73.48%, B = 73.01%, C = 79.26%; P = 0.428), good mucus quality (A = 96.45%, B = 91.30%, C = 93.45%; P = 0.203) and the presence of mounting lesions (A = 98.58, B = 94.93%, C = 98.13; P = 0.414). First-service pregnancy rates were 19.78%, 15.64% and 32.03% in Groups A, B and C, respectively (P = 0.003). There were no inter-group differences for the interval from parturition to first AI. However, a significantly shorter interval from parturition to conception (92.17 days, 99.45 days, 118.93 days; P = 0.002) and significantly less services per conception (2.12, 2.18, 2.66; P = 0.003) were observed in Groups A and B in comparison with Group C. The use of PGF2α resulted in better fertility in a repetitive, routine postpartum programme, although no differences between Dcloprostenol and dinoprost were detected.

1990 ◽  
Vol 70 (1) ◽  
pp. 129-133 ◽  
Author(s):  
J. R. GILES ◽  
L. H. THOMPSON ◽  
S. ARKINS ◽  
T. CAMACHO ◽  
P. A. EICHEN

In two different experiments crossbred gilts and(or) sows were used to investigate the effects of uterine exposure (prior to breeding) to nonviable semen (NS), seminal plasma (SP) or egg albumen (EA) on reproductive performance. Treatment solutions were infused via the cervix at estrus in gilts or within 2 d post-partum in sows. Females were artificially inseminated at the subsequent estrus. In the first experiment pregnancy rates for gilts infused with Beltsville Thawing Solution (BTS) as controls, NS or EA and subsequently inseminated, were 76, 85 and 54%, respectively, and were not significantly different among treatment groups. The number of total embryos (adjusted for number of corpora lutea) present at 38 d postinsemination was 9.6, 9.0 and 9.6, respectively, for BTS, ND and EA infused gilts and was not significantly different. Likewise, the number of live and dead embryos was not different among treatments. In the second experiment, the proportions of inseminated sows infused with BTS, NS or SP that subsequently farrowed were 87, 84 and 92%, respectively, and did not differ significantly among treatments. No significant differences were detected for the number of total, live or dead pigs born per litter among treatments. We conclude that uterine exposure to seminal proteins or egg albumen prior to breeding does not alter reproductive performance in gilts by 38 d of gestation. Also, the infusion of seminal proteins in sows shortly after parturition does not affect pregnancy rates or litter size at the subsequent farrowing. Key words: Reproductive efficiency, litter size, swine, artificial insemination


2001 ◽  
Vol 26 (2) ◽  
pp. 347-352 ◽  
Author(s):  
B. Grimard ◽  
G. Laumonnier ◽  
C. Ponsart ◽  
H. Fauxpoint ◽  
E. Barassin ◽  
...  

AbstractTwo studies (expt. 1, 185 cows in 1996/97; expt. 2, 168 cows in 1997/98) were conducted with Prim ‘Holstein dairy cows in the Mayenne region (France) to investigate suboestrus. Cows which had not been observed in oestrus since calving were allocated alternately to treatment groups between 60 and 90 days post partum. Expt. 1. Group 1: GnRH (Day 0, 100 μg im), PGF2α (Day 7, 25 mg im), GnRH (Day 9, 100 μg im) with artificial insemination (AI) Day 10. Group 2 : PGF2α (Day 0, 25 mg im), AI at oestrus or if oestrus not observed a second PGF2α injection was given (Day 13) with AI on Day 16 and Day 17. Expt. 2. Group 1 : GnRH (Day 0, 100 /μg im), PGF2α (Day 7, 25 mg im), GnRH (Day 9, 100 μg im) with AI at observed oestrus after Day 0 or at Day 10 if oestrus not observed. Group 2 : PGF2α (Day 0, 25 mg im), AI at oestrus, or if oestrus was not observed a second PGF2α injection was given (Day 13) and AI at observed oestrus. Progesterone was measured in serum at Day 0 and in milk at AI. Pregnancy diagnosis was performed by measuring bovine Pregnancy Specific Protein B (bPSPB) (Day 50 + 3) and confirmed by ultrasonography when the result was doubtful.In expt. 1, farmers observed 47/101 (46.9 %) of group 1 cows in oestrus, 33/91 on Day 10 and 10 before Day 10. The progesterone concentrations were compatible with oestrus in 69/86 (80%) of cows on Day 10. In group 2, 36/83 (43.4 %) of cows were inseminated after the first PGF2α injection. After the second PGF2 α, only 29/43 (67 %) of cows had a low progesterone concentration at AI. The pregnancy rates were 36.1% and 32.5 % for groups 1 and 2, respectively. In expt. 2, oestrus was observed in 31/93 (33.7 %) of group 1 cows. In group 2, 51/75 (66 %) of cows were inseminated after the first injection of PGF2α, 13/75 (17.3 %) after the second and 11/75 (14.7 %) were not seen in oestrus. Pregnancy rates were 53.7% and 53.3% in groups 1 and 2, respectively. In conclusion, it is recommended that suboestrus be treated with PGF2α followed by AI at observed oestrus when oestrus detection is good while, the use of GnRH + PGF2α + GnRH is recommended when oestrus detection is poor.


2020 ◽  
Vol 44 (1) ◽  
pp. 198-202
Author(s):  
S. M. O. C. Urom

The research was conducted for 90 days using 96 and 16 Nigeria indigenous hens and cocks respectively sexually matured (24 and 26 weeks old) to comparatively evaluate the effect of clomiphene citrate on the reproductive performance of Nigerian indigenous birds. The birds were divided into 2 groups of 48 hens per group respectively as group Aand group B. Group A were artificially inseminated while group B birds were naturally mated. Each group was divided into 4 treatment groups of 12 hens per treatment. Clomiphene citrate was administered at 0mg (control), 10mg, 20mg and 30mg levels to the treatment groups represented as T1AI T2AI T3AI and T4AI and T1NM , T2NU , T3NN and T4NM for artificially inseminated and Naturally mated hens respectively and T1C T2C T3C and T4C for the cocks. The birds were fed adlibitum with breeder's mash for hens and growers mash for cock while water was served regularly. Seven days after clomiphene citrate was administered. Birds for natural mating were paired with their respective cocks according to their treatment groups, while those for artificial insemination were inseminated using cocks in the same treatment group. The ration was 2:12. The result of this study indicated higher productivity in artificially inseminated hens between (50-76 eggs) than naturally mated hens which produce between 42-63 eggs within this period. Artificial insemination also showed higher fertility of (62 to 85.25%) than the naturally mated that recorded between 34.88% to 78.5% fertility but the naturally mated recorded hatchability of between 53.35% and 90.90% while artificially inseminated hens recorded between 46.15% and 90.32%. Artificial inseminated birds recorded between 3.7% and 33.85% and 3.57% and 20.15% dead in germ and dead in shell respectively, while naturally mated hens recorded between 3.78% and 19.21%, and 2.01% and 15.79% in dead in germ and dead in shell respectively. The result of this study shows that artificial inseminated birds treated with clomiphene citrate encourages egg production and fertility.


2007 ◽  
Vol 76 (2) ◽  
pp. 187-193
Author(s):  
T. Zelený ◽  
J. Zelený ◽  
V. Kroupová ◽  
P. Slavík

The objective of this study was to compare the efficiency of high and low Ca intake in cows with analytically defined levels of calcaemia, phosphoraemia and magnesaemia in the prepartal period, on their postpartal changes important for the diagnosis of postpartal diseases. In dairy cows (Czech Pied cattle) receiving a winter feed ration, the prepartal intake of Ca was adjusted from day 241 of pregnancy to 80% in group A (n = 15) and to 160% of the standard in group B (n = 9). In both groups the concentrations of Ca, P and Mg in blood serum were measured at the beginning of experimental diets, on day 12 before the expected parturition, and on days 1, 2, 3 and 4 after parturition. At the beginning of the experiment (42 days before parturition) the value of calcaemia was 1.82 ± 0.10 mmol l-1, phosphoraemia 1.61 ± 0.37 mmol l-1 and magnesaemia 0.74 ± 0.6 mmol l-1 of blood serum. After the 30-day feeding of experimental diet (day 12 before the expected parturition) higher hypocalcaemia was recorded in group A persisting to day 3 post partum. Phosphoraemia and magnesaemia were at the lower limit of reference values only from day 12 before the expected parturition to day 4 post partum. In group A three cows became recumbent until day 3 post partum with a decrease in magnesaemia below 0.5 mmol l-1. Phosphoraemia and magnesaemia were at the lower limit of reference values only from day 12 before the expected parturition to day 4 post partum. In group A three cows became downed until day 3 post partum with a decrease in magnesaemia below 0.5 mmol l-1. In group B with 160% intake of Ca, 12 days before the expected parturition calcaemia amounted to 2.20 ± 0.27 mmol l-1 and hypocalcaemia ranging from 1.60 ± 0.45 to 1.80 ± 0.26 mmol l-1 of blood serum persisted from day 1 to day 4 post partum. The average level of phosphoraemia in group B was maintained above 1.80 mmol l-1 and magnesaemia was within the range of 0.93 - 1.21 mmol l-1 of blood serum. The results of the nutrition experiment document that for the prepartal adjustment of Ca intake aimed at a reduction in the incidence of the postpartal downer cow syndrome, it is necessary to determine calcaemia, phosphoraemia and magnesaemia in late-pregnant cows. In hypocalcaemia, hypophosphoraemia and especially hypomagnesaemia the prepartal diet with 80% coverage of Ca need leads to a higher risk of the downer cow syndrome accompanied by higher hypomagnesaemia.


1998 ◽  
Vol 10 (2) ◽  
pp. 207 ◽  
Author(s):  
M. C. A. Smith ◽  
J. M. Wallace

To investigate the influence of early ovulation after calving on subsequent fertility, milk progesterone concentrations were monitored twice weekly in multiparous (n = 87) and primiparous (n = 60) Holstein/Friesian dairy cattle. Luteal activity before 21 days post partum was defined as ‘early’. In multiparous cows, calving-to-conception interval (CCI) was longer, services per cow were more numerous and conception rate to all inseminations was lower with early luteal activity (n = 41, 16·8±0·39 days post partum) than with later luteal activity (n = 46, 37·8±2·09 days post partum); multiparous cows with early luteal activity required more exogenous fertility treatments and were more likely to fail to conceive by 100 days post partum. In contrast, in primiparous cows, no significant relationships were detected between early (n = 32) or later (n = 28) luteal activity and the CCI, number of services per cow or conception rates to all inseminations. However, primiparous cows that ovulated before 21 days post partum had fewer normal progesterone profiles. Early ovulation after calving was associated with reduced pregnancy rates and prolonged CCIs in multiparous but not in primiparous dairy cows. Extra keyword: luteal function.


Obesity Facts ◽  
2021 ◽  
pp. 1-9
Author(s):  
Serdar Sahin ◽  
Havva Sezer ◽  
Ebru Cicek ◽  
Yeliz Yagız Ozogul ◽  
Murat Yildirim ◽  
...  

<b><i>Introduction:</i></b> The aim of this was to describe the predictors of mortality related to COVID-19 infection and to evaluate the association between overweight, obesity, and clinical outcomes of COVID-19. <b><i>Methods:</i></b> We included the patients &#x3e;18 years of age, with at least one positive SARS-CoV-2 reverse transcriptase-polymerase chain reaction. Patients were grouped according to body mass index values as normal weight &#x3c;25 kg/m<sup>2</sup> (Group A), overweight from 25 to &#x3c;30 kg/m<sup>2</sup> (Group B), Class I obesity 30 to &#x3c;35 kg/m<sup>2</sup> (Group C), and ≥35 kg/m<sup>2</sup> (Group D). Mortality, clinical outcomes, laboratory parameters, and comorbidities were compared among 4 groups. <b><i>Results:</i></b> There was no significant difference among study groups in terms of mortality. Noninvasive mechanical ventilation requirement was higher in group B and D than group A, while it was higher in Group D than Group C (Group B vs. Group A [<i>p</i> = 0.017], Group D vs. Group A [<i>p</i> = 0.001], and Group D vs. Group C [<i>p</i> = 0.016]). Lung involvement was less common in Group A, and presence of hypoxia was more common in Group D (Group B vs. Group A [<i>p</i> = 0.025], Group D vs. Group A [<i>p</i> &#x3c; 0.001], Group D vs. Group B [<i>p</i> = 0.006], and Group D vs. Group C [<i>p</i> = 0.014]). The hospitalization rate was lower in Group A than in the other groups; in addition, patients in Group D have the highest rate of hospitalization (Group B vs. Group A [<i>p</i> &#x3c; 0.001], Group C vs. Group A [<i>p</i> &#x3c; 0.001], Group D vs. Group A [<i>p</i> &#x3c; 0.001], Group D vs. Group B [<i>p</i> &#x3c; 0.001], and Group D vs. Group C [<i>p</i> = 0.010]). <b><i>Conclusion:</i></b> COVID-19 patients with overweight and obesity presented with more severe clinical findings. Health-care providers should take into account that people living with overweight and obesity are at higher risk for COVID-19 and its complications.


2008 ◽  
Vol 57 (6) ◽  
pp. 709-716 ◽  
Author(s):  
T. I. I. van der Kooi ◽  
M. Koningstein ◽  
A. Lindemans ◽  
D. W. Notermans ◽  
E. Kuijper ◽  
...  

The first Dutch outbreak due to Clostridium difficile ribotype 027 was observed in mid-2005; by the end of that year, eight hospitals were affected. To study the relationship between hospital-wide antibiotic use and the incidence of 027-linked C. difficile-associated disease (CDAD) three study groups were made: group A, all eight hospitals with an 027-associated epidemic; group B, five of a total of six hospitals with occasional 027 cases, without an increase in CDAD; and group C, ten randomly selected hospitals with no reported 027 epidemics or isolated 027 cases. Quarterly data on CDAD incidences, hygiene measures and the use of fluoroquinolones, second- and third-generation cephalosporins, extended-spectrum penicillins, penicillins with beta-lactamase inhibitors, carbapenems, lincomycins and macrolides were collected for 2004 and 2005, and divided into pre-epidemic and epidemic periods. Using a multilevel Poisson regression analysis, CDAD incidence was linked to antibiotic use in the previous quarter and to certain hygiene measures. In the pre-epidemic period, the total use of the studied antibiotics was comparable between affected and unaffected hospitals. Higher use of second-generation cephalosporins, macrolides and all of the studied antibiotics were independently associated with a small increase in CDAD incidence [relative risk (95 % confidence interval): 1.14 per increase of 100 defined daily doses per 10 000 bed days (1.06–1.23), 1.10 (1.01–1.19) and 1.02 (1.01–1.03), respectively]. However the effect was too small to predict which hospitals might be more prone to 027-associated outbreaks.


Author(s):  
Abubakr O. Ismail ◽  
◽  
Erneo B. Ochi ◽  
Ambrose S. Jubara ◽  
Bakri Ahmed A/Rahim ◽  
...  

A comparative hormonal study of prostaglandin, gonadotropin releasing hormone and their combination was conducted on 30 randomly selected cross-bred dairy cows of SEMEX project for artificial insemination in Hillat Kuku, Khartoum North, Sudan. The study attempts to determine the response of the animals to hormonal induction and synchronization of estrous as well as fertility following fixed time artificial insemination. Three treatment groups of 10 cows each were undertaken. Groups 1, 2 and 3 involved administration of prostaglandin F2α (PGF2α), gonadotropin releasing hormone (GnRH) and a combination of PGF2α + GnRH, respectively. Descriptive statistical analysis was performed. The results revealed that all the three protocols induced and synchronized estrous were almost synchronous in all the treated groups. However, protocol 3 revealed a significantly (p<0.05) better result of 70% pregnancy rate compared to other two protocols that equally provided 50% pregnancy rates. The study resolves that protocol 3 be highly recommended to change the mindset of farmers about the spread of reproductive technology in Sudan. Protocols 1 and 2 provided acceptable pregnancy rates that can be enhanced with the improvement of management.


2014 ◽  
Vol 29 (1-2) ◽  
pp. 1-7
Author(s):  
Khadiza Begum ◽  
Rokeya Begum ◽  
Qazi Shamima Akhter ◽  
Nusrat Sultana ◽  
Shamima Bari

Background: There is an association between breast feeding & maternal lipid profile. Pregnancy related hyperlipidaemia reverse quickly with lactation. Objective: To observe Serum Total cholesterol & triglyceride in lactating & nonlactating mother. Method: The present cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of July 2010 to June 2011. A total 300 subjects were included within the age limit from 20 to 40 years of women. Among them100 were normal healthy subjects & had child above 3 years were considered as group A (control). The rest 200 women were selected as study subject (group B) having child between the age 6 weeks to 2 years. Group B is again subdivided into group B1 (100 lactating mother) & group B2 (100 nonlactating mother). The subjects were selected from pediatric ward & OPD of pediatrics, DMCH and BSMMU, Dhaka. Data were collected in data collection sheet after taking informed written consent of the subjects. The study parameters total cholesterol & Triglyceride were done in the Department of Physiology, Dhaka Medical College. The data were analyzed by computer with SPSS programs using unpaired Student ?t’ test.Results: In group B1 total cholesterol & triglyceride levels were non significantly higher than that of group A but in group B2 these values were significantly higher than that of group A. Within the study groups all these values were significantly higher in nonlactating mother than lactating mother. It was observed that high level of study parameters were more in B2 than that of group B1. Conclusion: From the results of the present study it may be concluded that lactation has effect on lowering serum total cholesterol & triglyceride which may preferably related to health education for the mother. http://dx.doi.org/10.3329/bjpp.v29i1-2.20060Bangladesh J Physiol Pharmacol 2013; 29(1&2) : 1-7


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