scholarly journals A férfiak férfimeddőséggel kapcsolatos ismeretei és a támogatás lehetőségei: kockázati tényezők és egyéni válaszreakciók

2018 ◽  
Vol 159 (31) ◽  
pp. 1262-1268 ◽  
Author(s):  
Angelika Szatmári ◽  
Zsuzsanna Fejes ◽  
István Király

Abstract: In recent decades, the incidence of male infertility has been increasing continuously both worldwide and in Hungary and is becoming a more and more central issue. Millions of men at the reproductive age are affected by male infertility. In addition to the known organic reasons, many life-style and environmental factors can be expected to contribute to this. The biopsychosocial theoretical model of infertility allows us to interpret the lack of fertility not only from the medical point of view, but also as a psychosocial phenomenon. Men’s coping strategies, health information seeking habits, and knowledge of infertility are similar to women’s, but there are several different points in their responses given to the problem. So medical, nursing and other health professionals dealing with infertile male patients should devote special and high attention to patients’ conducting and paramedical counselling as supportive therapy. Within the framework of this – besides giving information – the individual support contributes to the elaboration of information, arising effects and experiences, furthermore to the developement of adaptive coping strategies for stress, and to the modification of direct or indirect changes in health behavior affecting reproductive health during the treatment period. Orv Hetil. 2018; 159(31): 1262–1268.

2013 ◽  
Vol 5 (2) ◽  
pp. 76-79
Author(s):  
KP Biswas ◽  
Jayesh Amin ◽  
Asit Kumar Dutta ◽  
Kumud Kunwar ◽  
Veena G Shinde ◽  
...  

ABSTRACT Rising number of infertile males in India provokes the need of evidence-based comprehensive formula addressing unattended causes of male infertility. There is an innovative product*, a combikit available in Indian market, containing 30 tablets of antioxidant, multivitamin, amino acid and mineral tablets, with documented evidence on ingredients in treatment of male infertility, and 25 tablets of clomiphene citrate which is a timetested drug in treatment of male infertility (in particular oligospermia and/or asthenospermia). In order to assess efficacy of the product in Indian infertile male patients, we undertook phase IV multicentric clinical study, at 18 centers across India in 100 patients. Very high couple pregnancy rate of 53% was reported. As first line treatment of male infertility (in particular oligospermia and/or asthenospermia), the use of this innovative product therefore holds a strong promise. How to cite this article Amin J, Mishra SK, Dutta AK, Kunwar K, Shinde VG, Chauhan A, Sud S, Maurya R, Nepal N, Sarode P, Biswas KP, Mazumder GP, Chitrabanshi M, Shibe S, Shukla R, Trivedi N, Dayal M, Sortey D, Shukla S, Gawade B. Indian Clinical Experience on Innovative Product in Treatment of Male Infertility. J South Asian Feder Obst Gynae 2013;5(2):76-79.


2020 ◽  
Author(s):  
Angelika Szatmári

Célok A tanulmány célja a Magyarországon eddig alig, vagy nem használt betegvezetési technikák alkalmazása meddőségi zavarokkal küzdő férfi betegek körében. A kezelés időszakában ¬az információk nyújtása mellett – az egyéni támogatás keretében hozzájárulni a keletkező hatások, tapasztalatok, ismeretek feldolgozásához, továbbá a stresszel való adaptív megküzdési stratégiák kialakításához, valamint a reproduktivitást befolyásoló egészségmagatartás változók közvetlen vagy közvetett módosításához. Közvetett célként tekintjük a kezelések, valamint a biztonságos betegellátás hatékonyságának támogatását az ellátottak ismereteinek bővítésével, továbbá a betegelégedettségi mutatók kedvező irányú változásának elősegítését. A rendelkezésre álló pszichológiai vizsgálóeszközök segítségével felmérni az általunk kidolgozott betegvezetési program hatékonyságát. Módszerek A vizsgálatot kizárólag férfi faktoros meddőséggel küzdők körében, kísérleti (N=57) és kontrollcsoport (N=51) keretében végeztük. A betegek részletes kivizsgálását, valamint a veszteségre adott válaszreakcióinak és a betegségükkel kapcsolatos tájékozottság felmérését követően a kísérleti csoport tagjai 5 alkalommal betegvezetésben részesültek. A kontrollcsoportnál a pszichológiai önjellemző diagnosztikai kérdőívek felvételére a kutatás elején és végén, a célcsoportoknál a foglalkozásokat megelőzően, majd azt követően került sor. Eredmények Az intervenciós csoport nagyfokú tudatossággal rendelkezett a diagnózisokról, valamint a javasolt kezelések természetéről és céljairól. Az intervenciós csoport szignifikánsan célirányos probléma fókuszú megküzdési stratégát alkalmazott a meddőségi kezelés során. A betegek a beavatkozással szembeni elégedettségről számoltak be, ami a kísérleti csoport BDI és STAI pontszámainak csökkenésében is tükröződik. Következtetés: A fertilitásproblémákkal küzdők számára paramedikális tanácsadással kedvezőbb pszichés jóllét biztosítható a professzionális segítők aktív közreműködésével. A páciensek hatékony, célzott és problémaspecifikus segítségnyújtásban részesülhetnek. A férfi-meddőség ellátásában kiemelt szerepet kell biztosítani az egészségügyi ellátók; az ápolók, a reproduktív orvoslás, a mentálhigiénés szakember által nyújtott paramedikális tanácsadásnak.


2017 ◽  
Vol 25 (3) ◽  
pp. 460-468 ◽  
Author(s):  
I. S. Sobennikov ◽  
B. N. Zhiborev ◽  
S. Ya. Kotans ◽  
A. A. Cherenkov

The article presents a study of reproductive function and fertility prognosis in 27 male patients of reproductive age with common diseases of genitals and inguinal region. These patients were under observation in the outpatient clinics with the diagnosis of male infertility. Blood levels of sex hormones and spermograms were evaluated in dynamics before and after surgical treatment of the main disease. In the research it was found that surgical removal of the probable cause of infertility in marriage resulted in normalization of spermogram parameters in 15% of cases and to the onset of pregnancy in 22.2% of cases. No significant changes in the dynamics of sex hormones were found. Besides, in the course of research a positive clinical effect of conservative treatment for the connective tissue dysplasia associated with the main disease and infertility in marriage, was obtained. This effect was confirmed by the onset of pregnancy in 29.4% of patients who underwent drug therapy.


2021 ◽  
Vol 6 (6) ◽  
pp. 8-14
Author(s):  
Mir Abid Jan ◽  
Arshad Arshad ◽  
Majid Khan Kakakhel ◽  
Muhammad Hamid

Objective:  This study is aimed to discuss the challenges in dealing the infertile male and advances in the treatment of male infertility. Material and methods: The study included infertile male patients who presented to andrology outpatient as primary or secondary infertility between December 2018 and January 2021. The data detailed different aspects of challenges and advances in male infertility treatment. The data analysisone with SPSS. Results: Total 289 patients included, most of them (74%) presented as primary infertility and a quarter presented as secondary infertility. The mean delay in presentation was 6.8 years which were due to treatment from non-andrologist doctors of different specialities (53.9%), hakims (15.2%), quacks (13.8%), gynaecologists (10.3%) and some were reluctant to tell their problem (6.5%). The diagnosis was N.O.A (42.9%), unexplained infertility (24.2%), varicocele (22.8%), OA (6.2%), OAT syndrome (2.7%) and CABVD (1%). Different treatment option opted were vasography plus vasovasostomy or vasoepididmostomy (31.1%), ART (23.9%), MSV (22.8%) and medical treatment (22.1%). Vasography plus vasovasostomy or vasoepididmostomy and medical treatment were the available options provided. There was no ART facility and those who were counseled for referral either their unwillingness or cost resulted in a hurdle in their provision. Conclusion: There are still a number of challenges in treating infertile men. Recently provision of medical and microsurgical treatment at andrology clinic resulted in proper treatment of a large number of infertile men who previously received treatment from un- related facilities.


2021 ◽  
Vol 43 (3) ◽  
pp. 1307-1324
Author(s):  
Ashutosh Vashisht ◽  
Pankaj Kumar Ahluwalia ◽  
Gagandeep Kaur Gahlay

(1) Background: The relationships between the biochemical and immunological components in seminal plasma and their physiological effects on male reproductive system have been underreported. In this study, we evaluated the potential of several seminal plasma biochemical and immunological markers in the pathophysiological developments of the infertile male patients. The study was designed to identify and assess different markers that may be associated with semen functions in different types of male infertility. (2) Methods: A total of 50 infertile male patients who underwent checkup for fertility assessment and 50 fertile controls were included in this study. The complete medical history of each recruited participant was reviewed. The infertile sub-groups (non-obstructive azoospermia (NOA), asthenozoospermia (AS), normozoospermic infertile (NI), and oligozoospermia (OZ)) were characterized based on sperm motility and concentration, while NI patients were included after a thorough check up of their female partners as well. We investigated each sample for 21 different analytes, enzymes, trace elements, and immunological markers to find crucial markers posing as contributing factors to a specific type of male infertility. (3) Results: The levels of 15 out of 21 markers, assayed from the seminal plasma of infertile males, were significantly altered in comparison to fertile controls (p < 0.05). For the first time, microprotein levels were also analyzed. The presence of monocytes, lymphocytes, and granulocytes was limited to semen from NOA patients, while a significant increase in the level of platelets was observed in AS. Hierarchical clustering and ROC-AUC analysis identified the three most significant markers (zinc, LDH, and TG) for the healthy control group and asthenozoospermic group (AUC, of 0.92 and 0.81, respectively). (4) Conclusions: The altered levels of biochemical and immunological markers in seminal plasma might be associated with the different male infertility profiles and could be required for the sperm metabolism and maintenance. However, a larger sample size and follow up analysis is required for establishing the hypothesized panel of markers as biomarkers at clinical stage.


2019 ◽  
pp. 22-29
Author(s):  
Н. В. Фрадкіна

The purpose and tasks of the work are to analyze the contemporary Ukrainian mass culture in terms of its value and humanistic components, as well as the importance of cultural studies and Ukrainian studies in educational disciplines for the formation of a holistic worldview of modern youth.Analysis of research and publications. Scientists repeatedly turned to the problems of the role of spirituality in the formation of society and its culture. This problem is highlighted in the publications by O. Losev, V. Lytvyn, D. Likhachev, S. Avierintsev, M. Zakovych, I. Stepanenko and E. Kostyshyn.Experts see the main negative impact of mass culture on the quality approach, which determines mass culture through the market, because mass culture, from our point of view, is everything that is sold and used in mass demand.One of the most interesting studies on this issue was the work by the representatives of Frankfurt School M. Horkheimer and T. Adorno «Dialectics of Enlightenment» (1947), devoted to a detailed analysis of mass culture. Propaganda at all socio-cultural levels in the form is similar in both totalitarian and democratic countries. It is connected, according to the authors, with the direction of European enlightenment. The tendency to unify people is a manifestation of the influence of mass culture, from cinema to pop. Mass culture is a phenomenon whose existence is associated with commerce (accumulation in any form – this is the main feature of education), in general, the fact that it exists in this form is related to the direction of the history of civilization.Modern mass culture, with its externally attractive and easily assimilated ideas and symbols, appealing to the trends of modern fashion, becomes a standard of prestigious consumption, does not require intense reflection, allows you to relax, distract, not teach, but entertains, preaches hedonism as the main spiritual value. And as a consequence, there are socio-cultural risks: an active rejection of other people, which leads to the formation of indifference; cruelty as a character trait; increase of violent and mercenary crime; increase in the number of alcohol and drug addicts; anti-patriotism; indifference to the values of the family and as a result of social orphanhood and prostitution.Conclusions, perspectives of research. Thus, we can conclude that modern Ukrainian education is predominantly formed by the values of mass culture. Namely, according to the «Dialectic» by Horkheimer and Adorno, «semi-enlightenment becomes an objective spirit» of our modern society.It is concluded that only high-quality education can create the opposite of the onset of mass culture and the destruction of spirituality in our society. It is proved that only by realizing the importance of cultivating disciplines in the educational process and the spiritual upbringing of the nation, through educational reforms, humanitarian knowledge will gradually return to student audiences.Formation of youth occurs under the influence of social environment, culture, education and self-education. The optimal combination of these factors determines both the process of socialization itself and how successful it will be. In this context, one can see the leading role of education and upbringing. It turns out that the main task of modern education is to spread its influence on the development of spiritual culture of the individual, which eventually becomes a solid foundation for the formation of the individual. Such a subject requires both philosophical and humanitarian approaches in further integrated interdisciplinary research, since the availability of such research will provide the theoretical foundation for truly modern educational and personal development.


2020 ◽  
Vol 29 (4) ◽  
pp. 556-563
Author(s):  
Adam Burley

This is a personal and reflective piece written from a clinician's point of view on the influence that the developing awareness around the consequences of childhood adversity has had upon the discussions, thinking and practice across the areas in which they are working. It seeks to argue that the increased understanding and recognition of the potential impact of early adversity can not only enhance and deepen the understanding of an individual's difficulties, but can serve to inform how services respond in a way that takes account of this. It suggests that the research and literature on childhood adversity can offer a route map away from a model of mental health that focuses predominantly on the individual as the sole source of interest.


2020 ◽  

BACKGROUND: This paper deals with territorial distribution of the alcohol and drug addictions mortality at a level of the districts of the Slovak Republic. AIM: The aim of the paper is to explore the relations within the administrative territorial division of the Slovak Republic, that is, between the individual districts and hence, to reveal possibly hidden relation in alcohol and drug mortality. METHODS: The analysis is divided and executed into the two fragments – one belongs to the female sex, the other one belongs to the male sex. The standardised mortality rate is computed according to a sequence of the mathematical relations. The Euclidean distance is employed to compute the similarity within each pair of a whole data set. The cluster analysis examines is performed. The clusters are created by means of the mutual distances of the districts. The data is collected from the database of the Statistical Office of the Slovak Republic for all the districts of the Slovak Republic. The covered time span begins in the year 1996 and ends in the year 2015. RESULTS: The most substantial point is that the Slovak Republic possesses the regional disparities in a field of mortality expressed by the standardised mortality rate computed particularly for the diagnoses assigned to the alcohol and drug addictions at a considerably high level. However, the female sex and the male sex have the different outcome. The Bratislava III District keeps absolutely the most extreme position. It forms an own cluster for the both sexes too. The Topoľčany District bears a similar extreme position from a point of view of the male sex. All the Bratislava districts keep their mutual notable dissimilarity. Contrariwise, evaluation of a development of the regional disparities among the districts looks like notably heterogeneously. CONCLUSIONS: There are considerable regional discrepancies throughout the districts of the Slovak Republic. Hence, it is necessary to create a common platform how to proceed with the solution of this issue.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Fatma Zehra Erbayram ◽  
Esma Menevse ◽  
Duygu Dursunoglu

Abstract Objectives We aimed to determine the differences between normozoospermic and oligozoospermic individuals according to levels of spermatid-specific thioredoxin reductase 3 (SPTRXR3/STRX3/TXNDC8/TXNRD3) and testis expressed protein 101 (TEX-101), and to evaluate the correlations between spermiogram data and biochemical parameters. Methods The study was carried out at the Andrology Laboratory of Medicine Faculty of Selcuk University. Two groups were designed: Group 1: Normozoospermia (n=40, sperm concentration ≥ 15 million/mL), Group 2: Oligozoospermia; (n=40, sperm concentration < 15 million/mL). Seminal plasma SPTRXR3 and TEX-101 levels were analyzed with ELISA method. Spermiogram analysis was evaluated according to WHO 2010 Kruger criteria. Results TEX-101 protein levels were significantly different in normozoospermia (2.12 ± 0.08 ng/mL) compared to oligozoospermia (1.55 ± 0.04 ng/mL). SPTRXR3 levels (6.98 ± 0.46 ng/mL) were higher in oligozoospermia than normozoospermia (3.07 ± 0.35 ng/mL). Both TEX-101 and SPTRXR3 levels were correlated statistically with most of the spermiogram parameters. Conclusions High SPTRXR3 and low TEX-101 levels may be a biomarker in evaluation of male infertility. The relations between spermiogram parameters indicates that results present a new clinical approach in biology of oligozoospermic male.


Materials ◽  
2021 ◽  
Vol 14 (8) ◽  
pp. 1986
Author(s):  
Andreas Koenig ◽  
Julius Schmidtke ◽  
Leonie Schmohl ◽  
Sibylle Schneider-Feyrer ◽  
Martin Rosentritt ◽  
...  

The performance of dental resin-based composites (RBCs) heavily depends on the characteristic properties of the individual filler fraction. As specific information regarding the properties of the filler fraction is often missing, the current study aims to characterize the filler fractions of several contemporary computer-aided design/computer-aided manufacturing (CAD/CAM) RBCs from a material science point of view. The filler fractions of seven commercially available CAD/CAM RBCs featuring different translucency variants were analysed using Scanning Electron Microscopy (SEM) with Energy Dispersive X-ray Spectroscopy (EDS), Micro-X-ray Computed Tomography (µXCT), Thermogravimetric Analysis (TG) and X-ray Diffractometry (XRD). All CAD/CAM RBCs investigated included midifill hybrid type filler fractions, and the size of the individual particles was clearly larger than the individual specifications of the manufacturer. The fillers in Shofu Block HC featured a sphericity of ≈0.8, while it was <0.7 in all other RBCs. All RBCs featured only X-ray amorphous phases. However, in Lava Ultimate, zircon crystals with low crystallinity were detected. In some CAD/CAM RBCs, inhomogeneities (X-ray opaque fillers or pores) with a size <80 µm were identified, but the effects were minor in relation to the total volume (<0.01 vol.%). The characteristic parameters of the filler fraction in RBCs are essential for the interpretation of the individual material’s mechanical and optical properties.


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