Plasma homocysteine and vascular disease in elderly patients with mental illness

2008 ◽  
Vol 46 (11) ◽  
Author(s):  
Karin Nilsson ◽  
Lars Gustafson ◽  
Björn Hultberg
Keyword(s):  
Mental Illness ◽  
Elderly Patients ◽  
Vascular Disease ◽  
Plasma Homocysteine

Plasma homocysteine—a marker of vascular disease in elderly patients with mental illness

2010 ◽  
Vol 43 (13-14) ◽  
pp. 1056-1059 ◽  
Author(s):  
Karin Nilsson ◽  
Lars Gustafson ◽  
Björn Hultberg
Keyword(s):  
Mental Illness ◽  
Elderly Patients ◽  
Vascular Disease ◽  
Plasma Homocysteine

Role of Inflammatory Markers in Elderly Type 2 Diabetic Patients with Mild Cognitive Impairment

2019 ◽  
Vol 15 (3) ◽  
pp. 247-253 ◽  
Author(s):  
Salwa S. Hosny ◽  
Ahmed M. Bahaaeldin ◽  
Mohamed S. Khater ◽  
Meram M. Bekhet ◽  
Hayam A. Hebah ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Elderly Patients ◽  
Vascular Disease ◽  
Plasma Glucose ◽  
Serum Levels ◽  
Diabetic Patients ◽  
Hs Crp ◽  
And Control

<P>Background: Type 2 diabetes (T2DM) is a risk factor for Alzheimer’s disease and mild cognitive impairment. The etiology of cognitive impairment in people with T2DM is uncertain but, chronic hyperglycemia, cerebral micro vascular disease, severe hypoglycemia, and increased prevalence of macro vascular disease are implicated. </P><P> Objectives: To determine the serum levels of soluble vascular adhesion molecule (sVCAM-1) and highly sensitive C-reactive protein (hs-CRP) in elderly type 2 diabetics with mild cognitive impairment (MCI). Methods: Our study was conducted on 90 elderly subjects (aged 60 years old or more). They were divided into Group І, 30 patients with T2DM and mild cognitive impairment, group ІІ, 30 patients with T2DM without cognitive impairment and group III, 30 healthy subjects as a control group. They were subjected to history taking, full clinical examination, anthropometric measurement, the Addenbrooke’s Cognitive Examination III (ACE---III 2012), Fasting plasma glucose, 2 hours plasma glucose, HbA1c, lipid profile, protein/creatinine ratio, serum sVCAM-1 and hs-CRP. Results: Serum levels of sVCAM-1 in diabetic elderly patients with MCI were significantly higher (946.7 ± 162.01 ng/ml) than diabetic elderly patients without cognitive impairment (479.06 ± 65.27 ng/ml) and control (263.7 ± 72.05 ng/ml) with (P=0.002). Serum levels of Hs-CRP in diabetic elderly patients with MCI were significantly higher than as diabetic elderly patients without cognitive impairment and control with (P=0.005). Conclusion: Elderly diabetic patients with mild cognitive impairment have higher levels of soluble adhesion molecules and markers of low-grade systemic inflammation than other groups.</P>

Effects of virtual reality exergame on psychophysiological and postural disorders in elderly patients

2021 ◽  
Author(s):  
AE Khizhnikova ◽  
AS Klochkov ◽  
AA Fuks ◽  
AM Kotov-Smolenskiy ◽  
NA Suponeva ◽  
...  
Keyword(s):  
Virtual Reality ◽  
Elderly Patients ◽  
Vascular Disease ◽  
Balance Control ◽  
Balance Training ◽  
Medical Problem ◽  
Rehabilitation Program ◽  
Advanced Age ◽  
Balance Impairment ◽  
Underlying Causes

Balance impairment at advanced age is a serious medical problem that often has significant implications and affects the quality of the patient’s life. Among the underlying causes are overall slowness of motor response and vestibular syndrome. Virtual reality exergames, including reaction and balance training, hold promise for managing balance dysfunction. The aim of this study was to investigate the effects of a combination rehabilitation program containing elements of virtual reality exergame on the postural and psychophysiological parameters of elderly patients with small vascular disease The study was conducted in 24 patients with small vascular disease (median age: 66 years). All patients underwent a virtual reality rehabilitation program. Psychophysiological, postural and clinical evaluations were performed at baseline and after the program was completed. Balance function measured on the Berg scale improved significantly and was 53 [52; 55] after the training program vs 50 [45; 54] at baseline (p < 0.05). The strategy of balance control also changed: the Romberg ratio was 266 [199.5; 478.5] before rehabilitation and 221 [149.25; 404] after the program was completed (p < 0.05). The most pronounced changes in the measured psychophysiological parameters occurred in the simple audiomotor reaction, which improved from 210 [174.25; 245.5] at baseline to 180.5 [170.5; 208] after rehabilitation (p < 0.05). Thus, the combination balance and reaction virtual reality training is an effective rehabilitation method for advanced-age patients with balance impairment.

The Maximin/Leximin Theory

2019 ◽  
pp. 116-141
Author(s):  
Torbjörn Tännsjö
Keyword(s):  
Mental Health ◽  
Mental Illness ◽  
Elderly Patients ◽  
Welfare State ◽  
General Result ◽  
Mental Disease ◽  
Point Of View ◽  
Life Extension ◽  
Long Time ◽  
Fierce Competition

The maximin/leximin theory is applied in real medical life. The general result, in relation to any welfare state assuming its global obligations, is that more resources ought to be directed to the care and cure of people suffering from mental illness; less should be spent on marginal life extension (especially among elderly patients).The urgency of mental health, when the matter is assessed from the point of view of the maximin/leximin theory, has to do with the fact that people often suffer for very long time from mental disease rendering it plausible to assume that many people in this category garner throughout their lives a net deficit in terms of happiness. Hence they are the patients who are worst off. The problem with marginal life extension among elderly patients has to do with the fact that many among them have throughout their long lives already garnered a lot of happiness. Now these people have to stand back when there is fierce competition for available medical resources.

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