scholarly journals Preparation and evaluation of highly dispersible and Ca2+ level responsive PEGylated calcium phosphate nanoparticle with PEG-block-poly(4-vinylbenzylphosphonate) for the application of drug carrier

2012 ◽  
Vol 37 (3) ◽  
pp. 337-340
Author(s):  
Kei Asai ◽  
Naoki Kanayama ◽  
Yukio Nagasaki
Keyword(s):  
Calcium Phosphate ◽  
Drug Carrier ◽  
Preparation And Evaluation ◽  
Calcium Phosphate Nanoparticle

Calcium phosphate nanoparticle-mediated transfection in 2D and 3D mono- and co-culture cell models

2019 ◽  
Vol 84 ◽  
pp. 391-401 ◽  
Author(s):  
Viktoriya Sokolova ◽  
Leonardo Rojas-Sánchez ◽  
Nataniel Białas ◽  
Nina Schulze ◽  
Matthias Epple
Keyword(s):  
Calcium Phosphate ◽  
Culture Cell ◽  
Cell Models ◽  
2D And 3D ◽  
Calcium Phosphate Nanoparticle

Calcium phosphate porous pellets as drug delivery systems: Effect of drug carrier composition on drug loading and in vitro release

2012 ◽  
Vol 32 (11) ◽  
pp. 2679-2690 ◽  
Author(s):  
Hiva Baradari ◽  
Chantal Damia ◽  
Maggy Dutreih-Colas ◽  
Etienne Laborde ◽  
Nathalie Pécout ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Calcium Phosphate ◽  
Drug Delivery Systems ◽  
Drug Carrier ◽  
Drug Loading ◽  
In Vitro Release ◽  
Delivery Systems ◽  
Vitro Release

scholarly journals Spherical calcium phosphate nanoparticle fillers allow polymer processing of bone fixation devices with high bioactivity

2009 ◽  
Vol 50 (5) ◽  
pp. 952-960 ◽  
Author(s):  
Dirk Mohn ◽  
Duygu Ege ◽  
Kirill Feldman ◽  
Oliver D. Schneider ◽  
Thomas Imfeld ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Polymer Processing ◽  
Bone Fixation ◽  
Fixation Devices ◽  
Calcium Phosphate Nanoparticle

scholarly journals Subcutaneous tissue response and osteogenic performance of calcium phosphate nanoparticle-enriched hydrogels in the tibial medullary cavity of guinea pigs

2013 ◽  
Vol 9 (3) ◽  
pp. 5464-5474 ◽  
Author(s):  
Matilde Bongio ◽  
Jeroen J.J. van den Beucken ◽  
M. Reza Nejadnik ◽  
Zeinab Tahmasebi Birgani ◽  
Pamela Habibovic ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Guinea Pigs ◽  
Subcutaneous Tissue ◽  
Medullary Cavity ◽  
Tissue Response ◽  
Calcium Phosphate Nanoparticle

Tracking the interaction of drug molecules with individual mesoporous amorphous calcium phosphate/ATP nanocomposites – an X-ray spectromicroscopy study

2020 ◽  
Vol 22 (23) ◽  
pp. 13108-13117
Author(s):  
Ying-Ying Jiang ◽  
Zhi-Qiang Wang ◽  
Jia-Tang Chen ◽  
Jun Li ◽  
Ying-Jie Zhu ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Adenosine Triphosphate ◽  
Amorphous Calcium Phosphate ◽  
Drug Carrier ◽  
X Ray ◽  
Drug Molecules ◽  
Important Drug

Adenosine triphosphate (ATP) biomolecules play critical roles during the formation of amorphous calcium phosphate composites (ACPC), and ACPC is an important drug carrier due to its significant advantages of biocompatibility and biodegradability.

Calcium Phosphate Nanoparticle-Based Systems for Therapeutic Delivery

2019 ◽  
pp. 147-164
Author(s):  
Yun Piao ◽  
Ho Pan Bei ◽  
Allison Tam ◽  
Yuhe Yang ◽  
Qiang Zhang ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Therapeutic Delivery ◽  
Calcium Phosphate Nanoparticle

scholarly journals A Review Paper on Biomimetic Calcium Phosphate Coatings

2015 ◽  
Vol 9 (1) ◽  
pp. 56-64 ◽  
Author(s):  
X. Lin ◽  
K. de Groot ◽  
D. Wang ◽  
Q. Hu ◽  
D. Wismeijer ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Drug Carrier ◽  
Chemical Properties ◽  
Giant Cells ◽  
Clinical Applications ◽  
Bone Morphogenetic Protein 2 ◽  
Crystalline Lattice ◽  
Calcium Phosphate Coating ◽  
Phosphate Coatings ◽  
Calcium Phosphate Coatings

Biomimetic calcium phosphate coatings have been developed for bone regeneration and repair because of their biocompatibility, osteoconductivity, and easy preparation. They can be rendered osteoinductive by incorporating an osteogenic agent, such as bone morphogenetic protein 2 (BMP-2), into the crystalline lattice work in physiological situations. The biomimetic calcium phosphate coating enables a controlled, slow and local release of BMP-2 when it undergoes cell mediated coating degradation induced by multinuclear cells, such as osteoclasts and foreign body giant cells, which mimics a physiologically similar release mode, to achieve sustained ectopic or orthotopic bone formation. Therefore, biomimetic calcium phosphate coatings are considered to be a promising delivery vehicle for osteogenic agents. In this review, we present an overview of biomimetic calcium phosphate coatings including their preparation techniques, physico-chemical properties, potential as drug carrier, and their pre-clinical application both in ectopic and orthotopic animal models. We briefly review some features of hydroxyapatite coatings and their clinical applications to gain insight into the clinical applications of biomimetic calcium phosphate coatings in the near future.

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