scholarly journals Monitoring diabetic retinopathy in children with insulin-dependent diabetes mellitus

1998 ◽  
Vol 44 (3) ◽  
pp. 3-7
Author(s):  
T. M. Milenkaya ◽  
L. N. Shcherbacheva ◽  
V. A. Peterkova ◽  
V. S. Terentyev ◽  
V. P. Maksimova ◽  
...  

A total of 185 children (93 boys and 92 girls) aged 6 months to 15 years and disease duration of 1 to 13 years, residents of different regions of Russia, were examined. Pathological changes of the retina caused by diabetes were detected on the fundus oculi of 56 (30.3%) children. In 42 (22.7%)) of these, the initial changes (solitary retinal hemorrhages, microaneurysms) and in 14 (7.6%)) more pronounced micro- vascular pathological changes typical of nonproliferative diabetic retinopathy were detected, in 2 patients - the proliferative stage. Later argon coagulation of the retina was carried out in 10 patients with nonproliferative diabetic retinopathy and in 2 with proliferative diabetic retinopathy. The initial stages of nonproliferative and proliferative diabetic retinopathy are an indication for laser coagulation in children. The status of 6 (50%) children improved in remote periods (6-24 months) after laser coagulation: hemorrhages resolved and microaneurysms decreased; in 4 (33.3%) children the process was stabilized. Deterioration was observed in 2 (16. 7%o) children with nonproliferative and proliferative diabetic retinopathy.

1998 ◽  
Vol 44 (4) ◽  
pp. 7-12
Author(s):  
T. M. Milenkaya ◽  
V. S. Terentyev ◽  
E. G. Bessmertnaya ◽  
I. I. Dedov

A total of 182 patients (95 men and 87 women) aged 15-49 years with insulin-dependent diabetes mellitus were treated using argon laser coagulation. Late results of laser therapy were followed up for 6 months to 3 years. In the patients with nonproliferative diabetic retinopathy (DR) on the fundus oculi the improvement consisted in partial resolution of solid exudative foci and retinal hemorrhages in 20%o of cases. In patients with preproliferative DR, soft exudative foci partially resolved and the number of retinal hemorrhages and microaneurysms decreased in 17%o of cases. In patients with proliferative DR, regressive development of proliferative tissue, desolation of newly formed vessels, and resolution of preretinal hemorrhages were observed in 13.9%o of cases. Stabilization for 3 years was attained in 75%) of patients with nonproliferative and proliferative and in 72.5%o of those with preproliferative DR.


2018 ◽  
Vol 9 (1) ◽  
pp. 93-97 ◽  
Author(s):  
Konstantinos Andreanos ◽  
Tryfon Rotsos ◽  
George Kymionis ◽  
Chryssanthi Koutsandrea ◽  
Athanasios Kotsolis ◽  
...  

Purpose: To report a case of foveal neovascularization in a patient with proliferative diabetic retinopathy as seen on optical coherence tomography angiography (OCT-A). Methods: Multimodal imaging was used for diagnostic investigation. Patient: A 61-year-old male with a 16-year history of insulin-dependent diabetes mellitus was referred to our medical retina department for examination and management. Meticulous fundus examination and multimodal imaging revealed proliferative diabetic retinopathy lesions, including neovascularization located in the foveal area. Results: OCT-A allowed us to detect the neovascular lesion, confirm that it originated from perifoveal capillaries, estimate its retinal depth, and evaluate the vessel blood flow in multiple layers. Conclusion: To the best of our knowledge this is the first report of OCT-A imaging of foveal neovascularization in diabetic retinopathy. OCT-A is a very useful examination for the diagnostic investigation of patients with diabetic retinopathy.


1988 ◽  
Vol 318 (4) ◽  
pp. 208-214 ◽  
Author(s):  
Robert C. Ramsay ◽  
Frederick C. Goetz ◽  
David E.R. Sutherland ◽  
S. Michael Mauer ◽  
Leslie L. Robison ◽  
...  

1994 ◽  
Vol 40 (5) ◽  
pp. 7-9
Author(s):  
L. N. Scherbachyova ◽  
N. B. Lebedev ◽  
A. P. Knyazeva ◽  
B. P. Mischenko

Activities of superoxide dismutase and glutathione peroxidase were measured in 60 children aged 5 to 15 with insulin-dependent diabetes of various degrees of compensation and duration. Measurements of glutathione peroxidase were found to be the most informative marker of the status of antioxidant defense system.


Sign in / Sign up

Export Citation Format

Share Document