Developing lipid-coated calcium carbonate/phosphate hybrid nanoparticles as a gene/drug co-delivery platform for combined cancer therapy

2019 ◽  
Author(s):  
Yilun Wu
Keyword(s):  
Calcium Carbonate ◽  
Cancer Therapy ◽  
Hybrid Nanoparticles ◽  
Delivery Platform

scholarly journals Advances in Lipid-Based Nanoparticles for Cancer Chemoimmunotherapy

Pharmaceutics ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 520
Author(s):  
Tianqi Wang ◽  
Yusuke Suita ◽  
Saradha Miriyala ◽  
Jordan Dean ◽  
Nikos Tapinos ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Cancer Therapy ◽  
Cancer Treatment ◽  
Clinical Translation ◽  
Hybrid Nanoparticles ◽  
Future Perspectives ◽  
Preclinical Research ◽  
Delivery Platform

Nanomedicines have shown great potential in cancer therapy; in particular, the combination of chemotherapy and immunotherapy (namely chemoimmunotherapy) that is revolutionizing cancer treatment. Currently, most nanomedicines for chemoimmunotherapy are still in preclinical and clinical trials. Lipid-based nanoparticles, the most widely used nanomedicine platform in cancer therapy, is a promising delivery platform for chemoimmunotherapy. In this review, we introduce the commonly used immunotherapy agents and discuss the opportunities for chemoimmunotherapy mediated by lipid-based nanoparticles. We summarize the clinical trials involving lipid-based nanoparticles for chemoimmunotherapy. We also highlight different chemoimmunotherapy strategies based on lipid-based nanoparticles such as liposomes, nanodiscs, and lipid-based hybrid nanoparticles in preclinical research. Finally, we discuss the challenges that have hindered the clinical translation of lipid-based nanoparticles for chemoimmunotherapy, and their future perspectives.

scholarly journals Reconstituted HDL: Drug Delivery Platform for Overcoming Biological Barriers to Cancer Therapy

2018 ◽  
Vol 9 ◽  
Author(s):  
Sangram Raut ◽  
Linda Mooberry ◽  
Nirupama Sabnis ◽  
Ashwini Garud ◽  
Akpedje Serena Dossou ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Biological Barriers ◽  
Delivery Platform

scholarly journals Mono-arginine Cholesterol-based Small Lipid Nanoparticles as a Systemic siRNA Delivery Platform for Effective Cancer Therapy

Theranostics ◽  
2016 ◽  
Vol 6 (2) ◽  
pp. 192-203 ◽  
Author(s):  
Jinju Lee ◽  
Phei Er Saw ◽  
Vipul Gujrati ◽  
Yonghyun Lee ◽  
Hyungjun Kim ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Sirna Delivery ◽  
Lipid Nanoparticles ◽  
Delivery Platform ◽  
Effective Cancer Therapy

Graphene as multifunctional delivery platform in cancer therapy

2017 ◽  
Vol 105 (8) ◽  
pp. 2355-2367 ◽  
Author(s):  
Mojgan Nejabat ◽  
Fahimeh Charbgoo ◽  
Mohammad Ramezani
Keyword(s):  
Cancer Therapy ◽  
Delivery Platform

Bioinspired Synthesis of Intrinsically 177Lu-Labeled Hybrid Nanoparticles for Potential Cancer Therapy

2020 ◽  
Vol 59 (52) ◽  
pp. 22492-22500
Author(s):  
Rubel Chakravarty ◽  
Apurav Guleria ◽  
Sachin Jadhav ◽  
Chandan Kumar ◽  
Anil Krishna Debnath ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Hybrid Nanoparticles ◽  
Bioinspired Synthesis ◽  
Potential Cancer

scholarly journals Self-Assembled Lipid−Polymer Hybrid Nanoparticles: A Robust Drug Delivery Platform

ACS Nano ◽  
2008 ◽  
Vol 2 (8) ◽  
pp. 1696-1702 ◽  
Author(s):  
Liangfang Zhang ◽  
Juliana M. Chan ◽  
Frank X. Gu ◽  
June-Wha Rhee ◽  
Andrew Z. Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hybrid Nanoparticles ◽  
Polymer Hybrid ◽  
Delivery Platform ◽  
Self Assembled

Construction of pH-responsive drug delivery platform with calcium carbonate microspheres induced by chitosan gels

2018 ◽  
Vol 44 (7) ◽  
pp. 7902-7907 ◽  
Author(s):  
Jingwei Wang ◽  
Yong Kong ◽  
Feng Liu ◽  
Dan Shou ◽  
Yongxin Tao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Calcium Carbonate ◽  
Ph Responsive ◽  
Delivery Platform

scholarly journals Size-Controlled Preparation and Behavior Study of Phospholipid–Calcium Carbonate Hybrid Nanoparticles

2020 ◽  
Vol Volume 15 ◽  
pp. 4049-4062 ◽  
Author(s):  
Cheng Wang ◽  
Shaoqing Chen ◽  
Lu Bao ◽  
Xuerong Liu ◽  
Fuqiang Hu ◽  
...  
Keyword(s):  
Calcium Carbonate ◽  
Hybrid Nanoparticles ◽  
Behavior Study ◽  
And Behavior ◽  
Controlled Preparation ◽  
Size Controlled
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