Phytochemical Constituents in Hexane Fraction of Costus afer Ker Gawl. Stem

2014 ◽  
Vol 2 (3) ◽  
pp. 66 ◽  
Author(s):  
Godswill N. Anyasor ◽  
Funmilayo D Onajobi ◽  
Odutola Osilesi ◽  
Olugbenga O Adebawo
Keyword(s):  
Hexane Fraction ◽  
Phytochemical Constituents ◽  
Costus Afer

Phytochemical Study and Antioxidant Activities on Extracts of the Leaves and Roots of Costus afer Ker Gawl. (Zingiberaceae)

2020 ◽  
Vol 36 (05) ◽  
pp. 804-811
Author(s):  
Coulibaly Wacothon Karime ◽  
Adiko N’dri Marcelline ◽  
Benie Anoubilé ◽  
Konan Yao Mokey Jean-Baptiste ◽  
Bea Gouanda Thibaut ◽  
...  
Keyword(s):  
Ethyl Acetate Extract ◽  
Antioxidant Activities ◽  
Phytochemical Screening ◽  
Phytochemical Study ◽  
Average Value ◽  
Dpph Method ◽  
Phytochemical Constituents ◽  
Leaves And Roots ◽  
Layer Chromatography ◽  
Costus Afer

The extracts of leaves and roots of Costus afer plant have been fully investigated in an attempt to determine their phytochemical constituents and antioxidant activities. Phytochemical screening carried out using thin layer chromatography (TLC) revealed the presence of several secondary metabolites in all the selected extracts of the plant. In addition, our results showed that the leaves of C. afer are the richest in polyphenols with an average value of 3416.25 μg EAG/g MS. The total flavonoid assay revealed a highest content in the leaves (8.02 %). Furthermore, studies of the antioxidant activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH•) method showed a significant effect compared to the reference vitamin C. Ethyl acetate extract of the leaves show a higher percentage of inhibition (83 %), followed the roots (69 %).

scholarly journals Phytochemical assessment of Iphiona aucheri (Bioss.) Anderb. and its cytotoxic, antioxidant and antidiabetic activities

2020 ◽  
Vol 49 (4) ◽  
pp. 913-918
Author(s):  
Muhammad Abdur Rehman Shah ◽  
Rahmat Ali Khan ◽  
Mushtaq Ahmed
Keyword(s):  
Brine Shrimp ◽  
Methanolic Extract ◽  
Antioxidant Activities ◽  
Hexane Fraction ◽  
Total Phenolic ◽  
Aqueous Fraction ◽  
Phenolic Contents ◽  
Total Phenolic Contents ◽  
Total Antioxidant ◽  
Phytochemical Constituents

The presence of phytochemical constituents and estimation of total phenolic contents in Iphiona aucheri (Bioss.) Anderb. stem and assessment of their cytotoxic, total antioxidant and anti-diabetic activity were investigated. All fractions were assessed for phytochemicals, cytotoxic activity, total phenolic contents, antioxidant and anti-diabetic characteristics. Saponins, glycosides, protein and amino acids, carbohydrates and flavonoids were found in aqueous fraction and methanolic extract while they were absent in n-hexane fraction except glycosides and protein. The crude methanolic extract (70.3 ± 1.9%) revealed highest brine shrimp mortalities. Except n-hexane fraction others indicated considerable antioxidant activities via DPPH, ABTS•+ and H2O2 assays. Crude methanolic extract expressed higher inhibition of α-amylase (60.71 ± 0.89%) than glucophage (54.92 ± 0.56%). Non significant correlation of total phenolic contents with percentage antioxidant and anti-diabetic activities of crude methanolic extract and its various fractions was observed in all cases.

Molecular Interactions and Docking Studies of the Phytochemical Constituents of Costus Afer against Therapeutic Targets of Type 2 Diabetes.

2017 ◽  
Vol 06 (03) ◽  
Author(s):  
Tope Gafar Atere ◽  
Oluseyi Adeboye Akinloye ◽  
Regina Ngozi Ugbaja ◽  
David Ajiboye Ojo ◽  
Damilohun Samuel Metibemu ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Molecular Interactions ◽  
Therapeutic Targets ◽  
Docking Studies ◽  
Phytochemical Constituents ◽  
Costus Afer
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