A Comparative Study of in Vitro Antioxidant Activity and Phytochemical Constituents of Methanol Extract of Aframomum Melegueta and Costus Afer Leaves

2015 ◽  
Vol 8 (4) ◽  
pp. 273-279 ◽  
Author(s):  
Tinu Okugbo ◽  
Okugbo Oriakhi
2012 ◽  
Vol 2 (2) ◽  
pp. S539-S542 ◽  
Author(s):  
Narender Prasad D ◽  
B Ganga Rao ◽  
E Sambasiva Rao ◽  
T Mallikarjuna Rao ◽  
VS Praneeth D

2014 ◽  
Vol 60 ◽  
pp. 246-254 ◽  
Author(s):  
Acácio Antonio Ferreira Zielinski ◽  
Charles Windson Isidoro Haminiuk ◽  
Aline Alberti ◽  
Alessandro Nogueira ◽  
Ivo Mottin Demiate ◽  
...  

Author(s):  
Urmila U. Tambewagh ◽  
Supada Rambhau Rojatkar

Objective: Objective of the present study was to carry out in vivo anti-inflammatory and in vitro antioxidant activity of methanol extract of aerial part of the Blumea eriantha DC belonging to family Asteraceae.Methods: The shade dried aerial part of B. eriantha (0.5 kg) was powdered and extracted with methanol (1.5 x 3L) at room temperature (24h x 3). After filtration combined all the three extracts and were concentrated on rotary evaporator under reduced pressure at 40 °C, thereby providing crude methanol extract which was subsequently employed for further studies. Anti-inflammatory effect was studied by carrageenan-induced paw edema model in rats at dose level 100, 200, and 400 mg/kg. Acute oral toxicity study and in vitro antioxidant potential of the extract was also studied. The in vitro antioxidant activity of methanol extract of aerial part of Blumea eriantha DC was evaluated against 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydrogen peroxide (H2O2) and hydroxyl (OH) radicalscavenging and reducing power assays.Results: The results indicate that methanol extract of Blumea eriantha (BEME, 400 mg/kg) exhibited significant inhibition (p<0.001) of increase in paw edema at 5th h. IC50 value of BEME showed significant antioxidant activity. The extract exhibits promising free radical scavenging effect of DPPH, H2O2, OH and reducing power in a dose-dependent manner up to 100µg/ml concentration while the reference standard Ascorbic acid demonstrated more scavenging potential than the methanol extract of Blumea eriantha The methanol extract was found to be safe at the dose of 2000 mg/kg.Conclusion: The results of the experimental study confirmed that methanol extract of Blumea eriantha DC possesses significant anti-inflammatory and antioxidant activity.


Author(s):  
Krishma M. Jadav ◽  
K. N. Ninge Gowda

Objective: Four different extracts of Araucaria columnaris (bark peel) and Cosmos sulphureus (flowers) were screened for their phytochemical composition, and free radical scavenging activities.Methods: DPPH method was used to test the antioxidant activity for extracts.Results: Among the different extracts tested, the methanol extract of both the plant species showed significant radical scavenging activities. Phytochemical analysis of the extracts revealed that the radical scavenging activities might be due to the presence of flavonoids, tannins and phenolic compounds.Conclusion: The results obtained suggest that Araucaria columnaris (bark peel) and Cosmos sulphureus(flowers) could be exploited in the treatment of various diseases like cancer, cardiovascular diseases and infection diseases.  


LWT ◽  
2021 ◽  
pp. 111941
Author(s):  
Adenilson Renato Rudke ◽  
Kátia Suzana Andrade ◽  
Simone Mazzutti ◽  
Acácio Antônio Ferreira Zielinski ◽  
Victor Rodrigues Alves ◽  
...  

2017 ◽  
Vol 21 (1) ◽  
pp. 1-10
Author(s):  
Banji Adaramola ◽  
Oluchi Otuneme ◽  
Adebayo Onigbinde ◽  
Kunle Orodele ◽  
Abimbola Aleshinloye ◽  
...  

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