Volumetric Optoacoustic Tomography of Deep Tissue Morphology and Function in Real Time

Author(s):  
X Luis Dean-Ben ◽  
Andreas Buehler ◽  
Vasilis Ntziachristos ◽  
Daniel Razansky
2018 ◽  
Author(s):  
Anna Adams ◽  
Radha Krishna Murthy Bulusu ◽  
Nikita Mukhitov ◽  
Jose Mendoza-Cortes ◽  
Michael Roper

In this work, we developed a microfluidic bioreactor for optimizing growth and maintaining structure and function of HepG2, and when desired, the device could be removed and the extracellular output from the bioreactor combined with enzymatic glucose reagents into a droplet-based microfluidic system. The intensity of the resulting fluorescent assay product in the droplets was measured, and was directly correlated to glucose concentration, allowing the effect of insulin on glucose consumption in the HepG2 cells to be observed and quantified online and in near real-time.


2018 ◽  
Author(s):  
Anna Adams ◽  
Radha Krishna Murthy Bulusu ◽  
Nikita Mukhitov ◽  
Jose Mendoza-Cortes ◽  
Michael Roper

In this work, we developed a microfluidic bioreactor for optimizing growth and maintaining structure and function of HepG2, and when desired, the device could be removed and the extracellular output from the bioreactor combined with enzymatic glucose reagents into a droplet-based microfluidic system. The intensity of the resulting fluorescent assay product in the droplets was measured, and was directly correlated to glucose concentration, allowing the effect of insulin on glucose consumption in the HepG2 cells to be observed and quantified online and in near real-time.


2008 ◽  
Vol 134 (4) ◽  
pp. A-688 ◽  
Author(s):  
Bhavik A. Patel ◽  
Xiaochun Bian ◽  
James Galligan ◽  
Greg M. Swain

2011 ◽  
Vol 4 (11) ◽  
pp. 1503-1517 ◽  
Author(s):  
Sravan Mandadi ◽  
Patricia J. Armati ◽  
Basil D. Roufogalis
Keyword(s):  

2015 ◽  
Vol 127 (21-22) ◽  
pp. 858-863 ◽  
Author(s):  
Halil Atas ◽  
Alper Kepez ◽  
Mehmet Bozbay ◽  
Dilek Seckin Gencosmanoglu ◽  
Altug Cincin ◽  
...  

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