scholarly journals Experimental generation of a flat-top beam profile in a stable ring cavity

2019 ◽  
Vol 44 (17) ◽  
pp. 4428
Author(s):  
A. López-Vázquez ◽  
Y. M. Torres ◽  
M. S. Billión ◽  
W. M. Pimenta ◽  
J. A. Franco-Villafañe ◽  
...  
Keyword(s):  
Ring Cavity ◽  
Beam Profile ◽  
Flat Top Beam ◽  
Stable Ring

A Nd: YAG laser with a flat-top beam profile and constant divergence

1997 ◽  
Vol 29 (2) ◽  
pp. 57-61 ◽  
Author(s):  
W.C. Yen ◽  
C.T. Huang ◽  
H.P. Liu ◽  
L.P. Lee
Keyword(s):  
Beam Profile ◽  
Yag Laser ◽  
Flat Top Beam

scholarly journals Improving Consistency of Photobiomodulation Therapy: A Novel Flat-Top Beam Hand-Piece versus Standard Gaussian Probes on Mitochondrial Activity

2021 ◽  
Vol 22 (15) ◽  
pp. 7788
Author(s):  
Andrea Amaroli ◽  
Praveen Arany ◽  
Claudio Pasquale ◽  
Stefano Benedicenti ◽  
Alessandro Bosco ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Molecular Mechanisms ◽  
Therapeutic Potential ◽  
Atp Synthesis ◽  
Beam Profile ◽  
Photobiomodulation Therapy ◽  
Mitochondrial Activity ◽  
Hand Piece ◽  
Fibre Probe ◽  
Flat Top Beam

The tremendous therapeutic potential of photobiomodulation therapy in different branches of medicine has been described in the literature. One of the molecular mechanisms for this treatment implicates the mitochondrial enzyme, cytochrome C oxidase. However, the efficacy and consistency of clinical outcomes with photobiomodulation treatments has been fiercely debated. This work was motivated by this need to improve photobiomodulation devices and delivery approaches. We designed a novel hand-piece with a flat-top beam profile of irradiation. We compared the beam profile versus a standard hand-piece and a fibre probe. We utilized isolated mitochondria and performed treatments at various spots within the beam, namely, the centre, left and right edge. We examined mitochondrial activity by assessing ATP synthesis with the luciferin/luciferase chemiluminescent method as a primary endpoint, while mitochondrial damage was assessed as the secondary endpoint. We observed a uniform distribution of the power density with the flat-top prototype compared to a wide Gaussian beam profile with the standard fibre and standard hand-piece. We noted increased production of ATP in the centre of all three beams with respect to the non-treated controls (p < 0.05). Both the fibre and standard hand-piece demonstrated less increase in ATP synthesis at the edges than the centre (p < 0.05). In contrast, ATP synthesis was increased homogenously in the flat-top handpiece, both in the centre and the edges of the beam. Fibre, standard hand-piece and the flat-top hand-piece prototype have discrete beam distribution characteristics. This significantly affected the mitochondrial activity with respect to their position within the treated areas. Flat-top hand-piece enhances the uniformity of photobiomodulation treatments and can improve the rigour and reproducibility of PBM clinical outcomes.

Flat-top beam profile generated using a fiber-bundle prism-coupled beam shaper

2011 ◽  
Vol 284 (12) ◽  
pp. 2817-2824 ◽  
Author(s):  
A. Haghighatzadeh ◽  
H. Golnabi
Keyword(s):  
Fiber Bundle ◽  
Beam Profile ◽  
Flat Top Beam

Flat top beam profile cavity prototype

2005 ◽  
Author(s):  
J. Agresti ◽  
E. D'Ambrosio ◽  
R. DeSalvo ◽  
J. Mackowski ◽  
A. Remillieux ◽  
...  
Keyword(s):  
Beam Profile ◽  
Flat Top Beam

An all-fiber self-mixing range finder with tunable fiber ring cavity laser source

2020 ◽  
pp. 1-1
Author(s):  
Yunkun Zhao ◽  
Chenchen Wang ◽  
Yuanyang Zhao ◽  
Desheng Zhu ◽  
Liang Lu
Keyword(s):  
Ring Cavity ◽  
Laser Source ◽  
Range Finder ◽  
Fiber Ring ◽  
Cavity Laser
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