scholarly journals Coherence scanning and phase imaging optical interference microscopy at the lateral resolution limit

2018 ◽  
Vol 26 (6) ◽  
pp. 7376 ◽  
Author(s):  
Peter Lehmann ◽  
Weichang Xie ◽  
Benedikt Allendorf ◽  
Stanislav Tereschenko
Keyword(s):  
Interference Microscopy ◽  
Lateral Resolution ◽  
Phase Imaging ◽  
Resolution Limit ◽  
Optical Interference

3D-Optical Interference Microscopy at the Lateral Resolution Limit

Fringe 2013 ◽  
2014 ◽  
pp. 677-682
Author(s):  
Peter Lehmann ◽  
Jan Niehues ◽  
Stanislav Tereschenko
Keyword(s):  
Interference Microscopy ◽  
Lateral Resolution ◽  
Resolution Limit ◽  
Optical Interference

3-D Optical Interference Microscopy at the Lateral Resolution

2014 ◽  
Vol 8 (4) ◽  
pp. 231-241 ◽  
Author(s):  
Peter Lehmann ◽  
Jan Niehues ◽  
Stanislav Tereschenko
Keyword(s):  
Interference Microscopy ◽  
Lateral Resolution ◽  
Optical Interference

Beyond the lateral resolution limit by phase imaging

2011 ◽  
Vol 16 (10) ◽  
pp. 106007 ◽  
Author(s):  
Yann Cotte ◽  
M. Fatih Toy ◽  
Christian Depeursinge
Keyword(s):  
Lateral Resolution ◽  
Phase Imaging ◽  
Resolution Limit

Beyond the lateral resolution limit by phase imaging

2011 ◽  
Author(s):  
Y. Cotte ◽  
M. Fatih Toy ◽  
C. Depeursinge
Keyword(s):  
Lateral Resolution ◽  
Phase Imaging ◽  
Resolution Limit

scholarly journals Quantitative Histopathology of Stained Tissues using Color Spatial Light Interference Microscopy (cSLIM)

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Hassaan Majeed ◽  
Adib Keikhosravi ◽  
Mikhail E. Kandel ◽  
Tan H. Nguyen ◽  
Yuming Liu ◽  
...  
Keyword(s):  
New Technologies ◽  
Imaging Modality ◽  
Interference Microscopy ◽  
Phase Imaging ◽  
Bright Field Image ◽  
Interferometric Imaging ◽  
Breast Cancer Patients ◽  
Prognostic Information ◽  
Light Interference ◽  
Tissue Phase

Abstract Tissue biopsy evaluation in the clinic is in need of quantitative disease markers for diagnosis and, most importantly, prognosis. Among the new technologies, quantitative phase imaging (QPI) has demonstrated promise for histopathology because it reveals intrinsic tissue nanoarchitecture through the refractive index. However, a vast majority of past QPI investigations have relied on imaging unstained tissues, which disrupts the established specimen processing. Here we present color spatial light interference microscopy (cSLIM) as a new whole-slide imaging modality that performs interferometric imaging on stained tissue, with a color detector array. As a result, cSLIM yields in a single scan both the intrinsic tissue phase map and the standard color bright-field image, familiar to the pathologist. Our results on 196 breast cancer patients indicate that cSLIM can provide stain-independent prognostic information from the alignment of collagen fibers in the tumor microenvironment. The effects of staining on the tissue phase maps were corrected by a mathematical normalization. These characteristics are likely to reduce barriers to clinical translation for the new cSLIM technology.

Enhancement of lateral resolution in confocal self-interference microscopy

2003 ◽  
Vol 28 (24) ◽  
pp. 2470 ◽  
Author(s):  
DongKyun Kang ◽  
DaeGab Gweon
Keyword(s):  
Interference Microscopy ◽  
Lateral Resolution
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