scholarly journals Correction propagation for user-assisted optical coherence tomography segmentation: general framework and application to Bruch’s membrane segmentation

2020 ◽  
Vol 11 (5) ◽  
pp. 2830
Author(s):  
Daniel Stromer ◽  
Eric M. Moult ◽  
Siyu Chen ◽  
Nadia K. Waheed ◽  
Andreas Maier ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
General Framework ◽  
Optical Coherence ◽  
Bruch's Membrane ◽  
Bruch’S Membrane ◽  
Membrane Segmentation

scholarly journals Effect of Hydroxychloroquine on the Retinal Layers: A Quantitative Evaluation with Spectral-Domain Optical Coherence Tomography

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Hasim Uslu ◽  
Bulent Gurler ◽  
Aydin Yildirim ◽  
Mehmet Gurkan Tatar ◽  
Feride Aylin Kantarcı ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Outer Segment ◽  
Spectral Domain ◽  
Inner Plexiform Layer ◽  
Optical Coherence ◽  
Bruch's Membrane ◽  
Bruch’S Membrane ◽  
Control Subjects ◽  
Membrane Complex ◽  
Sd Oct

Purpose.To evaluate the effect of hydroxychloroquine on retinal pigment epithelium- (RPE-) Bruch’s membrane complex, photoreceptor outer segment, and macular ganglion cell-inner plexiform layer (GCIPL) thicknesses using spectral-domain optical coherence tomography (SD-OCT).Methods.In this prospective case-control study, 51 eyes of 51 hydroxychloroquine patients and 30 eyes of 30 healthy subjects were included. High-quality images were obtained using a Cirrus HD-OCT with 5-line raster mode; the photoreceptor inner segment (IS) and outer segment (OS), sum of the segments (IS + OS), and RPE-Bruch’s membrane complex were analyzed.Results.The thicknesses of the IS + OS and OS layers were significantly lower in the hydroxychloroquine subjects compared to the control subjects (P<0.05). RPE-Bruch’s membrane complex thicknesses were significantly higher in the hydroxychloroquine subjects than for those of the control subjects (P<0.05). The minimum and temporal-inferior macular GCIPL thicknesses were significantly different between the patients with hydroxychloroquine use and the control subjects (P=0.04andP=0.03, resp.).Conclusions.The foveal photoreceptor OS thinning, loss of GCIPL, and RPE-Bruch’s membrane thickening were detected in patients with hydroxychloroquine therapy. This quantitative approach using SD-OCT images may have important implications to use as an early indicator of retinal toxicity without any visible signs of hydroxychloroquine retinopathy.

scholarly journals Optical coherence tomography analysis of evolution of Bruch’s membrane features in angioid streaks

Eye ◽  
2017 ◽  
Vol 31 (11) ◽  
pp. 1600-1605 ◽  
Author(s):  
A Marchese ◽  
M Parravano ◽  
A Rabiolo ◽  
A Carnevali ◽  
E Corbelli ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Angioid Streaks ◽  
Bruch's Membrane ◽  
Bruch’S Membrane ◽  
Tomography Analysis
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