scholarly journals Anionic Hapten-Antibody Reactions on Various Cationic Bilayer Membrane Systems

1992 ◽  
Vol 24 (10) ◽  
pp. 1017-1024
Author(s):  
Hirotaka Ihara ◽  
Tomoaki Arimura ◽  
Takashi Imamura ◽  
Eiko Satoh ◽  
Toyoki Kunitake ◽  
...  
Keyword(s):  
Bilayer Membrane ◽  
Membrane Systems

scholarly journals Localization of trehalose in partially hydrated DOPC bilayers: insights into cryoprotective mechanisms

2014 ◽  
Vol 11 (95) ◽  
pp. 20140069 ◽  
Author(s):  
Ben Kent ◽  
Taavi Hunt ◽  
Tamim A. Darwish ◽  
Thomas Hauß ◽  
Christopher J. Garvey ◽  
...  
Keyword(s):  
Experimental Data ◽  
Lipid Bilayer ◽  
Molecular Mechanisms ◽  
Biological Membranes ◽  
Water Layer ◽  
Bilayer Membrane ◽  
Lipid Bilayer Membrane ◽  
Membrane Systems ◽  
Gaussian Profile

Trehalose, a natural disaccharide with bioprotective properties, is widely recognized for its ability to preserve biological membranes during freezing and dehydration events. Despite debate over the molecular mechanisms by which this is achieved, and that different mechanisms imply quite different distributions of trehalose molecules with respect to the bilayer, there are no direct experimental data describing the location of trehalose within lipid bilayer membrane systems during dehydration. Here, we use neutron membrane diffraction to conclusively show that the trehalose distribution in a dioleoylphosphatidylcholine (DOPC) system follows a Gaussian profile centred in the water layer between bilayers. The absence of any preference for localizing near the lipid headgroups of the bilayers indicates that the bioprotective effects of trehalose at physiologically relevant concentrations are the result of non-specific mechanisms that do not rely on direct interactions with the lipid headgroups.

scholarly journals Improved membrane fluidity of ionic polysaccharide bead-supported phospholipid bilayer membrane systems

2013 ◽  
Vol 107 ◽  
pp. 90-96 ◽  
Author(s):  
Mamoru Haratake ◽  
Ekuko Takahira ◽  
Sakura Yoshida ◽  
Samuel Osei-Asante ◽  
Takeshi Fuchigami ◽  
...  
Keyword(s):  
Membrane Fluidity ◽  
Bilayer Membrane ◽  
Phospholipid Bilayer ◽  
Membrane Systems ◽  
Phospholipid Bilayer Membrane
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