scholarly journals 5-Azacytidine-induced Apoptosis in the Central Nervous System of Developing Rat Fetuses

1998 ◽  
Vol 11 (2) ◽  
pp. 133-133 ◽  
Author(s):  
Dong-ping Lu ◽  
Hiroyuki Nakayama ◽  
Junko Shinozuka ◽  
Koji Uetsuka ◽  
Ryuichi Taki ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Rat Fetuses ◽  
The Central Nervous System ◽  
Induced Apoptosis ◽  
Developing Rat

Low concentrations of hydrogen sulphide alter monoamine levels in the developing rat central nervous system

1992 ◽  
Vol 70 (11) ◽  
pp. 1515-1518 ◽  
Author(s):  
B. Skrajny ◽  
R. S. Hannah ◽  
S. H. Roth
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Frontal Cortex ◽  
Hydrogen Sulphide ◽  
Chronic Exposure ◽  
Brain Regions ◽  
Target Organs ◽  
Low Concentrations ◽  
The Central Nervous System ◽  
Developing Rat

The central nervous system is one of the primary target organs for hydrogen sulphide (H2S) toxicity; however, there are limited data on the neurotoxic effects of low-dose chronic exposure on the developing nervous system. Levels of serotonin and norepinephrine in the developing rat cerebellum and frontal cortex were determined following chronic exposure to 20 and 75 ppm H2S during perinatal development. Both monoamines were altered in rats exposed to 75 ppm H2S compared with controls; serotonin levels were significantly increased at days 14 and 21 postnatal in both brain regions, and norepinephrine levels were significantly increased at days 7, 14, and 21 postnatal in cerebellum and at day 21 in the frontal cortex. Exposure to 20 ppm H2S significantly increased the levels of serotonin in the frontal cortex at day 21, whereas levels of norepinephrine were significantly reduced in the frontal cortex at days 14 and 21, and at day 14 in the cerebellum.Key words: hydrogen sulphide, monoamines, serotonin, norepinephrine, neurotoxicity.

5-Azacytidine (5AzC)-induced histopathological changes in the central nervous system of rat fetuses

2002 ◽  
Vol 54 (2) ◽  
pp. 91-96 ◽  
Author(s):  
Masaki Ueno ◽  
Kei-ichi Katayama ◽  
Akira Yasoshima ◽  
Hiroyuki Nakayama ◽  
Kunio Doi
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Histopathological Changes ◽  
Rat Fetuses ◽  
The Central Nervous System

scholarly journals Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system

2000 ◽  
Vol 97 (2) ◽  
pp. 889-894 ◽  
Author(s):  
M. J. Chong ◽  
M. R. Murray ◽  
E. C. Gosink ◽  
H. R. C. Russell ◽  
A. Srinivasan ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Ionizing Radiation ◽  
Radiation Induced ◽  
The Central Nervous System ◽  
Induced Apoptosis

A method for detection of a cytokine and its mRNA in the central nervous system of the developing rat

1999 ◽  
Vol 4 (3) ◽  
pp. 271-279 ◽  
Author(s):  
Tomoharu Suzuki ◽  
Akihiko Ogata ◽  
Kunio Tashiro ◽  
Kazuo Nagashima ◽  
Mamoru Tamura ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
The Central Nervous System ◽  
Developing Rat
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