scholarly journals Analysis of hydroxylated metabolites of PCBs (OH-PCBs) and other chlorinated phenolic compounds in whole blood from Canadian inuit.

2000 ◽  
Vol 108 (7) ◽  
pp. 611-616 ◽  
Author(s):  
C D Sandau ◽  
P Ayotte ◽  
E Dewailly ◽  
J Duffe ◽  
R J Norstrom
Keyword(s):  
Phenolic Compounds ◽  
Whole Blood ◽  
Hydroxylated Metabolites ◽  
Chlorinated Phenolic Compounds

Determination of Phenol and Chlorinated Phenolic Compounds Based on a PPO-Bioelectrode and Its Inhibition

1995 ◽  
Vol 28 (3) ◽  
pp. 405-424 ◽  
Author(s):  
J. L. Besombes ◽  
S. Cosnier ◽  
P. Labbé ◽  
G. Reverdy
Keyword(s):  
Phenolic Compounds ◽  
Chlorinated Phenolic Compounds

scholarly journals The Changes of Blood Platelet Reactivity in the Presence of Crude Extracts Isolated from Leaves and Twigs of Elaeagnus Rhamnoides (L.) A. Nelson Measuring in Whole Blood

2021 ◽  
Author(s):  
Bartosz Skalski ◽  
Joanna Rywaniak ◽  
Jerzy Żuchowski ◽  
Anna Stochmal ◽  
Beata Olas
Keyword(s):  
Phenolic Compounds ◽  
Platelet Activation ◽  
Whole Blood ◽  
Leaf Extract ◽  
Platelet Reactivity ◽  
Blood Platelets ◽  
Blood Platelet ◽  
Surface Expression ◽  
Sea Buckthorn ◽  
Crude Extracts

Abstract Uncontrolled blood platelet activation is an important risk factor of cardiovascular disease (CVDs). Various studies on phenolic compounds indicate that they have a protective effect on the cardiovascular system through different mechanisms, including the reduction of blood platelet activation. One of the plants that is particularly rich in phenolic compounds is sea buckthorn (Elaeagnus rhamnoides (L.) A. Nelson). The aim of the present study in vitro was to determine the anti-platelet properties of crude extracts isolated from leaves and twigs of E. rhamnoides (L.) A. Nelson in whole blood using flow cytometric and total thrombus-formation analysis system (T-TAS). The aim of our study was also analyze of blood platelet proteoms in the presence of different sea buckthorn extracts. A significant new finding is a decrease surface expression of P-selectin on blood platelets stimulated by 10 µM ADP and 10 µg/mL collagen, and a decrease surface expression of GPIIb/IIIa active complex on non-activated platelets and platelets stimulated by 10 µM ADP and 10 µg/mL collagen in the presence of sea buckthorn leaf extract (especially at the concentration 50 µg/mL). The twig extract also displayed antiplatelet potential. However, this activity was higher in the leaf extract than in the twig extract in whole blood. In addition, our present findings clearly demonstrate that investigated plant extracts have anticoagulant properties (measured by T-TAS). Therefore, the two tested extracts may be promising candidates for the natural anti-platelet and anticoagulant supplements.

Aqatic toxicity equivalency factors for chlorinated phenolic compounds present in pulp mill effluents

1993 ◽  
Vol 12 (2) ◽  
pp. 281-289 ◽  
Author(s):  
T. G. Kovacs ◽  
P. H. Martel ◽  
R. H. Voss ◽  
P. E. Wrist ◽  
R. F. Willes
Keyword(s):  
Phenolic Compounds ◽  
Pulp Mill ◽  
Equivalency Factors ◽  
Pulp Mill Effluents ◽  
Chlorinated Phenolic Compounds
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