scholarly journals Drug-Induced Interstitial Lung Diseases Associated with Molecular-Targeted Anticancer Agents

2009 ◽  
Vol 76 (1) ◽  
pp. 4-8 ◽  
Author(s):  
Akihiko Gemma
Keyword(s):  
Anticancer Agents ◽  
Lung Diseases ◽  
Interstitial Lung Diseases ◽  
Drug Induced

scholarly journals Drugs associated with drug-induced interstitial lung diseases

2021 ◽  
pp. 39-51
Author(s):  
O. D. Ostroumova ◽  
A. I. Listratov ◽  
A. I. Kochetkov ◽  
D. A. Sychev
Keyword(s):  
Respiratory Failure ◽  
Lung Diseases ◽  
Underlying Disease ◽  
Interstitial Lung Diseases ◽  
Diagnostic Methods ◽  
Lung Damage ◽  
Close Monitoring ◽  
Disease Treatment ◽  
Drug Induced ◽  
The Relationship

Interstitial lesion is one of the causes of respiratory failure. Drugs are a modifiable etiological factor of lung damage. Medications most commonly associated with drug-induced interstitial lung disease include antineoplastic drugs, disease-modifying anti-rheumatic drugs and amiodarone. According to the latest literature data, the previously described link between anti-rheumatic drugs and interstitial lung diseases is very inconsistent. It may even be a protective effect of this group of drugs on the lung tissue. The relationship between statin use and interstitial lesions is also complex and not fully understood. It is necessary to carefully assess the appearance of respiratory tract complaints in patients taking statins as in other groups of patients. Prescription of additional diagnostic methods is necessary to close monitoring and prevention the toxic effect of these drugs. These actions, as well as the potential prescription of steroid therapy and change in the underlying disease treatment approaches, are an important factor in reducing the incidence of respiratory failure in the population.

scholarly journals HRCT Patterns of Drug-Induced Interstitial Lung Diseases: A Review

Diagnostics ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 244 ◽  
Author(s):  
Giulio Distefano ◽  
Luigi Fanzone ◽  
Monica Palermo ◽  
Francesco Tiralongo ◽  
Salvatore Cosentino ◽  
...  
Keyword(s):  
Interstitial Pneumonia ◽  
Drug Toxicity ◽  
Lung Diseases ◽  
Diffuse Alveolar Damage ◽  
Usual Interstitial Pneumonia ◽  
Interstitial Lung Diseases ◽  
High Resolution Computed Tomography ◽  
Drug Induced ◽  
Pubmed Database ◽  
Hrct Patterns

Interstitial Lung Diseases (ILDs) represent a heterogeneous group of pathologies, which may be related to different causes. A low percentage of these lung diseases may be secondary to the administration of drugs or substances. Through the PubMed database, an extensive search was performed in the fields of drug toxicity and interstitial lung disease. We have evaluated the different classes of drugs associated with pulmonary toxicity. Several different high resolution computed tomography (HRCT) patterns related to pulmonary drug toxicity have been reported in literature, and the most frequent ILDs patterns reported include Nonspecific Interstitial Pneumonia (NSIP), Usual Interstitial Pneumonia (UIP), Hypersensitivity Pneumonitis (HP), Organizing Pneumonia (OP), Acute Respiratory Distress Syndrome (ARDS), and Diffuse Alveolar Damage (DAD). Finally, from the electronic database of our Institute we have selected and commented on some cases of drug-induced lung diseases related to the administration of common drugs. As the imaging patterns are rarely specific, an accurate evaluation of the clinical history is required and a multidisciplinary approach—involving pneumologists, cardiologists, radiologists, pathologists, and rheumatologists—is recommended.

scholarly journals ROLE OF HIGH RESOLUTION COMPUTED TOMOGRAPHY IN THE EVALUATION OF INTERSTITIAL LUNG DISEASES

2021 ◽  
pp. 1-3
Author(s):  
Sanjib Saha ◽  
Debasish Dakshit ◽  
Debarshi Jana
Keyword(s):  
Chest Radiography ◽  
Lung Diseases ◽  
Imaging Modality ◽  
Lung Parenchyma ◽  
Interstitial Lung Diseases ◽  
High Resolution Computed Tomography ◽  
Drug Induced ◽  
Cross Sectional ◽  
Medical College ◽  
Radiation Induced

Background: Interstitial lung diseases are classified into those with known causes and with unknown causes. Those with known causes include Connective tissue disease associated ILD, Pneumoconiosis, Drug-induced, Smoking-related ILD, Radiation-induced and Toxic inhalation–induced ILD. Those with unknown causes include Idiopathic pulmonary fibrosis, Sarcoidosis, Pulmonary lymph a goalie myomitosis and pulmonary alveolar protein sis. Amis: To utilize HRCT in evaluation of pulmonary interstitium in patients having clinical features of interstitial lung diseases. To compare the accuracies of chest radiography and HRCT in the prediction of specific diagnosis of interstitial lung disease. Material and methods: Hospital based observational study. CT section at Dept. Of Radio diagnosis, Medical College Kolkata (Philips brilliance 16 slice) and EKO diagnostics at Medical College, Kolkata. Dept. Of Radio diagnosis, Medical College, Kolkata. January 2018 to June 2019. Result: 2(4.0%) patients had ≤30 years of age, 9(18.0%) patients had 31-40 years of age, 15(30.0%) patients had 41-50 years of age, 18(36.0%) patients had 51-60 years of age, 3(6.0%) patients had 61-70 years of age and 3(6.0%) patients had >70 years of age. Conclusion: HRCT is the most accurate non-invasive imaging modality for evaluation of lung parenchyma in the cases of interstitial lung diseases. The cross sectional perspective and high spatial resolution makes HRCT superior to chest radiography.

Lung ultrasound in the evaluation of interstitial lung diseases

2016 ◽  
Vol 37 (S 01) ◽  
Author(s):  
N Buda ◽  
M Piskunowicz ◽  
M Porzezińska ◽  
W Kosiak ◽  
Z Zdrojewski
Keyword(s):  
Lung Diseases ◽  
Lung Ultrasound ◽  
Interstitial Lung Diseases

Characteristics of the immune and cytokine status in patients with interstitial lung diseases

2018 ◽  
Vol 1 (1) ◽  
pp. 25-29
Author(s):  
Mirgolib RAКHIMOV ◽  
◽  
Nematilla ARALOV ◽  
Shukhrat Ziyadullaev
Keyword(s):  
Lung Diseases ◽  
Interstitial Lung Diseases
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