CAUSATIVE DRUGS AND CLINICAL CHARACTERISTICS OF DRUG-INDUCED INTERSTITIAL LUNG DISEASES BY SPONTANEOUS REPORTS IN KOREA

Respirology ◽  
2017 ◽  
Vol 22 ◽  
pp. 201-201
Keyword(s):  
Lung Diseases ◽  
Clinical Characteristics ◽  
Interstitial Lung Diseases ◽  
Drug Induced ◽  
Spontaneous Reports

scholarly journals Clinical Characteristics and Predictors of the Recurrence of Organising Pneumonia Associated with Rheumatoid Arthritis

2020 ◽  
Author(s):  
Ryosuke Kamei ◽  
HIROYUKI YAMASHITA ◽  
Yuko Takahashi ◽  
Hiroshi Kaneko
Keyword(s):  
Rheumatoid Arthritis ◽  
Lung Diseases ◽  
Clinical Characteristics ◽  
Recurrence Risk ◽  
Interstitial Lung Diseases ◽  
High Recurrence Rate ◽  
Free Survival ◽  
First Recurrence ◽  
Study Participants ◽  
The Relationship

Abstract Background: Organizing pneumonia (OP) accounts for ~10% of the interstitial lung diseases in patients diagnosed with rheumatoid arthritis (RA). There are only a few published studies that have described RA-associated OP (RA–OP), each with comparatively few study participants. Furthermore, despite the high frequency of secondary flareups, no studies to date have identified factors that predict RA–OP recurrence. This study aimed to clarify the clinical characteristics of RA–OP, to determine the relationship between OP and RA exacerbations, and to identify predictors of RA–OP disease recurrence.Methods: The data of 33 patients with RA–OP admitted to our hospital between 2006 and 2016 were retrospectively analysed.Results: RA onset preceded OP in 82% of patients; OP preceded or co-occurred with RA in 9% each. The median [Q1, Q3] age at first OP onset was 64.0 [55.0, 68.0] years and 5.5 [1.0, 19.3] years after RA onset. At OP onset, 42% of events exhibited unilateral shadows and 76% had normal KL-6; RA disease control remained good in 52% and was exacerbate d in only 18%. Ten (30%) patients experienced OP recurrence with an interval of 13.0 [7.5, 22.5] months between events, with a rate of first recurrence of 127 per 1,000 person-years. Compared with 14 non-recurrent cases, 10 recurrent cases showed lower age at first OP (59.5 years vs. 67.1 years; p = 0.043) and shorter period from RA to first OP (6.4 vs. 14.2 years; p = 0.047) and included more OP-preceding patients (30% vs. 0%; p = 0.029) and more ever-smokers (80% vs. 36%; p = 0.032). OP-preceding patients showed shorter median recurrence-free survival time (15 vs. 136 months; p = 0.009) and higher recurrence risk (hazard ratio, 5.5; p = 0.021). Conclusions: RA–OP showed a high recurrence rate but no association with RA exacerbation. Four predictors of RA–OP recurrence were identified.

scholarly journals Clinical characteristics of non-idiopathic pulmonary fibrosis, progressive fibrosing interstitial lung diseases

Medicine ◽  
2021 ◽  
Vol 100 (13) ◽  
pp. e25322
Author(s):  
Masamichi Komatsu ◽  
Hiroshi Yamamoto ◽  
Yoshiaki Kitaguchi ◽  
Satoshi Kawakami ◽  
Mina Matsushita ◽  
...  
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Lung Diseases ◽  
Clinical Characteristics ◽  
Interstitial Lung Diseases

Unclassifiable interstitial lung diseases: Clinical characteristics and survival

Respirology ◽  
2016 ◽  
Vol 22 (3) ◽  
pp. 494-500 ◽  
Author(s):  
Charlotte Hyldgaard ◽  
Elisabeth Bendstrup ◽  
Athol U. Wells ◽  
Ole Hilberg
Keyword(s):  
Lung Diseases ◽  
Clinical Characteristics ◽  
Interstitial Lung Diseases

CURRENT FEATURES OF NON-SPECIFIC INTERSTITIAL PNEUMONIA

2020 ◽  
Vol 93 (1) ◽  
pp. 11-13
Author(s):  
Nematillo Aralov ◽  
Nargiza Makhmatmuradova ◽  
Parvina Zakiryaeva
Keyword(s):  
Medical Association ◽  
Retrospective Analysis ◽  
Interstitial Pneumonia ◽  
Lung Diseases ◽  
Clinical Characteristics ◽  
Interstitial Lung Diseases ◽  
Frequency Of Occurrence ◽  
Case Histories ◽  
Working Age ◽  
Nonspecific Interstitial Pneumonia

In order to study the frequency of occurrence, clinical characteristics, and diagnosis of interstitial pneumonia in the pulmonary department of hospitals, a retrospective analysis of case histories of 22 patients with nonspecific interstitial pneumonia who were hospitalized in the pulmonology department of the Samarkand city medical association in 2018-2019 was performed. An increase was found in patients with interstitial lung diseases, which are observed more often in women of working age, with prevalence of dyspnea, weakness, cough in the clinic, and the importance of the use of imaging technologies is indicated. Consultation of a pulmonologist is recommended for patients with rheumatic diseases.

scholarly journals Drugs associated with drug-induced interstitial lung diseases

2021 ◽  
pp. 39-51
Author(s):  
O. D. Ostroumova ◽  
A. I. Listratov ◽  
A. I. Kochetkov ◽  
D. A. Sychev
Keyword(s):  
Respiratory Failure ◽  
Lung Diseases ◽  
Underlying Disease ◽  
Interstitial Lung Diseases ◽  
Diagnostic Methods ◽  
Lung Damage ◽  
Close Monitoring ◽  
Disease Treatment ◽  
Drug Induced ◽  
The Relationship

Interstitial lesion is one of the causes of respiratory failure. Drugs are a modifiable etiological factor of lung damage. Medications most commonly associated with drug-induced interstitial lung disease include antineoplastic drugs, disease-modifying anti-rheumatic drugs and amiodarone. According to the latest literature data, the previously described link between anti-rheumatic drugs and interstitial lung diseases is very inconsistent. It may even be a protective effect of this group of drugs on the lung tissue. The relationship between statin use and interstitial lesions is also complex and not fully understood. It is necessary to carefully assess the appearance of respiratory tract complaints in patients taking statins as in other groups of patients. Prescription of additional diagnostic methods is necessary to close monitoring and prevention the toxic effect of these drugs. These actions, as well as the potential prescription of steroid therapy and change in the underlying disease treatment approaches, are an important factor in reducing the incidence of respiratory failure in the population.

CLINICAL CHARACTERISTICS OF INTERSTITIAL LUNG DISEASES ADMITTED TO THE INTENSIVE CARE UNIT

2002 ◽  
Vol 30 (Supplement) ◽  
pp. A127
Author(s):  
Claudia I Olvera ◽  
Liliana Rojas ◽  
Joel O Ortega ◽  
Julio C Robledo
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Lung Diseases ◽  
Clinical Characteristics ◽  
Interstitial Lung Diseases
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