scholarly journals Effects of Egg Yolk Proteins on the Longitudinal Bone Growth of Adolescent Male Rats

2004 ◽  
Vol 68 (11) ◽  
pp. 2388-2390 ◽  
Author(s):  
Kang-Hyun LEEM ◽  
Myung-Gyou KIM ◽  
Hyun-Mi KIM ◽  
Mujo KIM ◽  
Young-Ja LEE ◽  
...  
2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Mijung Yeom ◽  
Sung-Hun Kim ◽  
Bina Lee ◽  
Xiuyu Zhang ◽  
Hyangsook Lee ◽  
...  

Longitudinal bone growth is the results of chondrocyte proliferation and hypertrophy and subsequent endochondral ossification in the growth plate. Recently, laser acupuncture (LA), an intervention to stimulate acupoint with low-level laser irradiation, has been suggested as an intervention to improve the longitudinal bone growth. This study investigated the effects of laser acupuncture on growth, particularly longitudinal bone growth in adolescent male rats. Laser acupuncture was performed once every other day for a total of 9 treatments over 18 days to adolescent male rats. Morphometry of the growth plate, longitudinal bone growth rate, and the protein expression of BMP-2 and IGF-1 in growth plate were observed. The bone growth rate and the heights of growth plates were significantly increased by laser acupuncture. BMP-2 but not IGF-1 immunostaining in growth plate was increased as well. In conclusion, LA promotes longitudinal bone growth in adolescent rats, suggesting that laser acupuncture may be a promising intervention for improving the growth potential for children and adolescents.


2003 ◽  
Vol 17 (9) ◽  
pp. 1113-1116 ◽  
Author(s):  
K. Leem ◽  
S. Y. Park ◽  
D. H. Lee ◽  
Y. M. Boo ◽  
K. H. Cho ◽  
...  

1983 ◽  
Vol 244 (2) ◽  
pp. E135-E140 ◽  
Author(s):  
J. O. Jansson ◽  
S. Eden ◽  
O. Isaksson

In this study the mechanisms by which sex steroids influence body growth were investigated. The effect of different doses of testosterone propionate on longitudinal bone growth and body weight gain was studied in a) gonadectomized male rats, b) gonadohypophysectomized male rats, and c) gonadohypophysectomized male rats given replacement therapy with bovine growth hormone (bGH). The effect of different doses of estradiol benzoate on the same growth parameters was studied in female rats divided into the same experimental groups as the males. Accumulated longitudinal bone growth was determined using oxytetracycline as an intravital marker. Testosterone caused a dose-dependent increase in longitudinal bone growth in gonadectomized male rats. In contrast, testosterone exerted no significant increase in longitudinal bone growth in gonadohypophysectomized male rats with and without bGH replacement therapy. Treatment with estrogen inhibited longitudinal bone growth and body weight gain. The inhibitory effect of estradiol was approximately the same in gonadohypophysectomized female rats given bGH replacement therapy as in gonadectomized female rats. The results suggest that testosterone exerts its stimulatory effect on body growth mainly by modulating hypothalamopituitary functions, e.g., by altering the secretory pattern of GH. On the other hand, it seems that changes in the hypothalamopituitary functions are less significant for the inhibitory effect of estradiol on body growth. It is concluded from this study that the sites of action for estrogen and testosterone in modulating body growth in the rat are different.


2016 ◽  
Vol 19 (1) ◽  
pp. 73-84 ◽  
Author(s):  
Yun-Young Choi ◽  
Yuri Choi ◽  
Jisook Kim ◽  
Hyeonhae Choi ◽  
Jiwon Shin ◽  
...  

2019 ◽  
Vol 28 ◽  
pp. 170-176 ◽  
Author(s):  
Qiping Zhan ◽  
Yingying Tian ◽  
Yufeng Dai ◽  
Yanqi Li ◽  
Yuanyuan Li ◽  
...  

1984 ◽  
Vol 107 (2) ◽  
pp. 192-198 ◽  
Author(s):  
A. Skottner ◽  
A. Forsman ◽  
E. Löfberg ◽  
K.-G. Thorngren

Abstract. In hypophysectomized male rats the biological effects of two batches of methionyl human growth hormone, Somatonorm®, (met-hGH), have been compared to those of human pituitary growth hormone, Crescormon® (hGH). The rats were treated with doses ranging from 10 mIU per day to 145 mIU per day for 10 days. The parameters studied were total weight gain, longitudinal bone growth, measured by the tetracycline method and indirect cartilage growth, measured by uptake of radioactive sulphate. The results obtained demonstrated that Somatonorm® stimulated weight increase in a linear and dose-dependent way, similar to that seen with the native hormone. Longitudinal bone growth, measured by the tetracycline method and the growth of different cartilages, measured as uptake of radioactive sulphate, were also similar between the two hormones.


Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
JY Kim ◽  
SH Lee ◽  
J Park ◽  
MY Kim ◽  
GT Chang ◽  
...  

1978 ◽  
Vol 19 (1A) ◽  
pp. 97-105 ◽  
Author(s):  
A. S. Aronson ◽  
L. I. Hansson ◽  
G. Selvik

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