Effects of Dietary Lipid Peroxidation Products on Hormonal Responses in Primary Cultured Hepatocytes of Rats

1997 ◽  
Vol 61 (12) ◽  
pp. 2089-2094
Author(s):  
Hitoshi Ashida ◽  
Kenichi Ohue ◽  
Kazuki Kanazawa ◽  
Gen-ichi Danno
Keyword(s):  
Lipid Peroxidation ◽  
Dietary Lipid ◽  
Cultured Hepatocytes ◽  
Hormonal Responses ◽  
Lipid Peroxidation Products ◽  
Primary Cultured Hepatocytes

scholarly journals Endotoxin associated lipid peroxidation of the primary cultured hepatocytes. Involvement of Kupffer cells.

Kanzo ◽  
1994 ◽  
Vol 35 (8) ◽  
pp. 601-608
Author(s):  
Taisei MUTOH ◽  
Masanori SUZUKI ◽  
Kenji FUKUHARA ◽  
Koji ITOH ◽  
Kojin ENDOH ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Kupffer Cells ◽  
Cultured Hepatocytes ◽  
Primary Cultured Hepatocytes

scholarly journals PSVII-17 Program Chair Poster Pick: Reproductive function of cows depending on lipid metabolism

2020 ◽  
Vol 98 (Supplement_4) ◽  
pp. 293-294
Author(s):  
Murat Baymishev ◽  
Sergey Eremin ◽  
Kirill Plemyashov ◽  
Khamidulla Baymishev ◽  
Igor Konopel’tsev ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Live Weight ◽  
Reproductive Function ◽  
Serum Levels ◽  
Total Serum ◽  
Dry Period ◽  
Lipid Peroxidation Products ◽  
Synthetic Function ◽  
The Difference ◽  
Oxidized Products

Abstract The aim of the study was to determine the etiopathogenesis of reproductive dysfunction in highly productive cows. Studies were conducted on cows of black-motley breed, aged 3–5 lactations, with a live weight of 480–520 kg. Cows were divided into two groups. The first group included 20 cows effective inseminated after the first insemination. The second group included 17 cows that did not fertilize after the first insemination. Blood samples (n = 253) were taken from 4–7; 14–17; 24–34; 35–50; 88–95; 195–210 days of pregnancy; during the beginning of dry period (DP); 1–4 days before calving and on the first day after calving. The content of total serum lipids in pregnant animals was 15.8% higher compared to unfertilized animals. In non-pregnant cows, a decrease in free cholesterol (by 28.65%), especially in its ether-bound fraction (14.91%), indicates a lower synthetic function of the liver, which is confirmed by the low serum levels of vitamins A and E (a difference of 11.3 and 23.65%). The DP was characterized by a significant increase in the products of lipid peroxidation - malondialdehyde by 12–17%, diene and triene conjugates - by 10–15 and 8–15%, respectively, and 1–4 days before calving in cows, which subsequently had a pathological calving, in particular - retention of placenta (5 cows), were characterized by an increased content in the blood plasma of lipid peroxidation products. Thus, the difference in the number of dienes, trienes, and malondialdehyde products was 14.0, 12.0, and 23.5%, compared with animals without obstetric pathology. On the first day after calving, this difference increased even more. Cows with retention of placenta had a significantly higher level of lipid peroxidation products and were characterized by a predominance of oxidized products over the antiradical thiol disulfide and ascorbate systems restored in the antioxidant balance.

Degradation of endogenous proteins and internalized asialofetuin in primary cultured hepatocytes of rats

1989 ◽  
Vol 21 (5) ◽  
pp. 483-495 ◽  
Author(s):  
Hisanori Kato ◽  
Shin-Ichiro Takahashi ◽  
Akio Takenaka ◽  
Ryuhei Funabiki ◽  
Tadashi Noguchi ◽  
...  
Keyword(s):  
Cultured Hepatocytes ◽  
Primary Cultured Hepatocytes ◽  
Endogenous Proteins

Hormonal Regulation of Aldolase B Gene Expression in Rat Primary Cultured Hepatocytes

1998 ◽  
Vol 350 (2) ◽  
pp. 291-297 ◽  
Author(s):  
Jun-itsu Ito ◽  
Takejiro Kuzumaki ◽  
Kaoru Otsu ◽  
Yoshihito Iuchi ◽  
Kiichi Ishikawa
Keyword(s):  
Gene Expression ◽  
Hormonal Regulation ◽  
Cultured Hepatocytes ◽  
Primary Cultured Hepatocytes ◽  
Aldolase B
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