scholarly journals Whole-Body Retention of 60CoCl2 and 58Co-Cyanocobalamin in Young and Adult Rats

1976 ◽  
Vol 17 (4) ◽  
pp. 240-246 ◽  
Author(s):  
Y. NISHIMURA ◽  
J. INABA ◽  
R. ICHIKAWA
Keyword(s):  
Whole Body ◽  
Adult Rats ◽  
Body Retention

scholarly journals Whole-body Retention and Tissue Distribution of Cesium-134 in New-born, Young and Adult Rats

1967 ◽  
Vol 8 (3-4) ◽  
pp. 132-140 ◽  
Author(s):  
Jiro INABA ◽  
Naonori MATSUSAKA ◽  
Ryushi ICHIKAWA
Keyword(s):  
Tissue Distribution ◽  
Whole Body ◽  
Adult Rats ◽  
New Born ◽  
Body Retention

Radioimmunszintigraphie mit SPECT: Methodik, Probleme und klinische Erfahrungen

1987 ◽  
Vol 26 (05) ◽  
pp. 202-205 ◽  
Author(s):  
J. Fass ◽  
S. Truong ◽  
U. Büll ◽  
V. Schumpelick ◽  
R. Bares
Keyword(s):  
Clinical Practice ◽  
The Other ◽  
Whole Body ◽  
Blood Clearance ◽  
Planar Scintigraphy ◽  
Gastrointestinal Carcinomas ◽  
Body Regions ◽  
Other Hand ◽  
Body Retention ◽  
Klinische Erfahrungen

Radioimmunoscintigraphy (RIS) with 111ln- and 131 I-labelled monoclonal anti bodies (MAbs) against CEA and/or CA 19-9 was performed in 83 patients with various gastrointestinal carcinomas. A total of 276 body regions could be examined. The results of planar scintigraphy and SPECT were compared intraindividually. Using 111 In-labelled MAbs the sensitivity of RIS was significantly improved by SPECT (88.9 vs. 52.4% with planar scintigraphy, p <0.01). For131 l-labelled MAbs the effect was smaller (83.9 vs. 65.6% with planar scintigraphy, n.s.). This finding can be explained by different kinetics and biodistribution of the used MAb preparations.111 In-labelled MAbs with long whole-body retention and rapid blood clearance reveal ideal qualities for SPECT; on the other hand, the short whole-body retention of131 l-labelled MAbs leads to small count rates and therefore long counting times that make delayed SPECT unsuitable in clinical practice

scholarly journals Improved zinc and iron absorption from breakfast meals containing malted oats with reduced phytate content

1996 ◽  
Vol 76 (5) ◽  
pp. 677-688 ◽  
Author(s):  
Marie Larsson ◽  
Lena Rossander-Hulthén ◽  
Brittmarie Sandström ◽  
Ann-Sofie Sandberg
Keyword(s):  
Iron Absorption ◽  
Human Subjects ◽  
Vulnerable Groups ◽  
Whole Body ◽  
Absolute Amount ◽  
Average Increase ◽  
Mineral Deficiency ◽  
Breakfast Meal ◽  
Body Retention ◽  
Phytate Content

The absorption of Zn or Fe from breakfast meals containing oat porridge prepared from malted and soaked oats and a control porridge made from untreated oats was measured in human subjects. The effect on Zn and Fe absorption of reducing the phytate content of oat-porridge meals was examined in each subject by extrinsic labelling of porridge with 65Zn and of bread rolls with 55Fe and 59Fe, and measuring whole-body retention and the erythrocyte uptake of isotopes. Each experiment comprised nine to ten subjects. The absorption of Zn from malted-oat porridge with a phytate (inositol hexaphosphate) content of 107 μmol was 18·3%, and significantly higher (P < 0·05) than from the control porridge containing 432 μmol phytate (11·8%). Fe absorption from the meal containing malted-oat porridge with 107 μmol phytate (Expt 2) was also significantly improved (P < 0·05) compared with that from the meal containing control porridge with 437 μmol phytate. The average increase in Fe absorption was 47%, or from 4·4 to 6·0%. In the breakfast meal containing malted porridge with 198 μmol phytate (Expt 3) the increase in Fe absorption was not significantly improved. Even though the phytate content was reduced to a greater extent in Expt 3 than Expt 2, the average increase in Fe absorption in Expt 3 was only 25% more than that from the meal containing control porridge (with 599 μmol phytate), depending on the higher absolute amount of phytate. In conclusion, an improvement in Zn and Fe absorption from oat products can be achieved by practising malting and soaking in the processing of oats. This may be of importance in the prevention of mineral deficiency in vulnerable groups.

Gastrointestinal iron and cobalt absorption and iron status in young rats and guinea pigs

1995 ◽  
Vol 14 (12) ◽  
pp. 949-954 ◽  
Author(s):  
Gpl Naylor ◽  
JD Harrison
Keyword(s):  
Guinea Pig ◽  
Guinea Pigs ◽  
Iron Status ◽  
Age Groups ◽  
Gastrointestinal Absorption ◽  
Whole Body ◽  
Suckling Period ◽  
Young Rats ◽  
Body Retention ◽  
Different Ages

The gastrointestinal absorption of Fe and Co by rats and guinea pigs of different ages was measured by comparing the whole-body retention of 59Fe and 57Co after oral and intraperitoneal administrations. The age-groups studied included newborn, weanlings and adults. The absorption of both Fe and Co decreased markedly with age in both rats and guinea pigs. In the rat, absorption remained ele vated during the suckling period, while in the guinea pig absorption decreased markedly during suckling. In both species, Fe and Co absorption were similar, and remained elevated above adult values for some time after weaning. The generally greater absorption of Fe and Co by rats than by guinea pigs and the longer duration of maximal absorp tion in the rats may have involved differences in Fe status in the two species and differences in the timing of gut mat uration.

scholarly journals Comparison of whole body retention of I-131 in case humans thyroid cancer between model prediction and measurement

2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Brudecki Kamil ◽  
Mroz Tomasz ◽  
Janowski Paweł ◽  
Lorenc-Brudecka Jadwiga
Keyword(s):  
Thyroid Cancer ◽  
Model Prediction ◽  
Whole Body ◽  
Body Retention

scholarly journals Lithium Content of 160 Beverages and Its Impact on Lithium Status in Drosophila melanogaster

Foods ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 795 ◽  
Author(s):  
Ulrike Seidel ◽  
Katharina Jans ◽  
Niklas Hommen ◽  
Ignacio R Ipharraguerre ◽  
Kai Lüersen ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Inductively Coupled Plasma ◽  
Mineral Water ◽  
Reference Value ◽  
Energy Drinks ◽  
Mineral Waters ◽  
Whole Body ◽  
Human Consumption ◽  
Lithium Content ◽  
Body Retention

Lithium (Li) is an important micronutrient in human nutrition, although its exact molecular function as a potential essential trace element has not yet been fully elucidated. It has been previously shown that several mineral waters are rich and highly bioavailable sources of Li for human consumption. Nevertheless, little is known about the extent in which other beverages contribute to the dietary Li supply. To this end, the Li content of 160 different beverages comprising wine and beer, soft and energy drinks and tea and coffee infusions was analysed by inductively coupled plasma mass spectrometry (ICP-MS). Furthermore, a feeding study in Drosophila melanogaster was conducted to test whether Li derived from selected beverages changes Li status in flies. In comparison to the average Li concentration in mineral waters (108 µg/L; reference value), the Li concentration in wine (11.6 ± 1.97 µg/L) and beer (8.5 ± 0.77 µg/L), soft and energy drinks (10.2 ± 2.95 µg/L), tea (2.8 ± 0.65 µg/L) and coffee (0.1 ± 0.02 µg/L) infusions was considerably lower. Only Li-rich mineral water (~1600 µg/L) significantly increased Li concentrations in male and female flies. Unlike mineral water, most wine and beer, soft and energy drink and tea and coffee samples were rather Li-poor food items and thus may only contribute to a moderate extent to the dietary Li supply. A novelty of this study is that it relates analytical Li concentrations in beverages to Li whole body retention in Drosophila melanogaster.

EFFECTS OF EXPOSURE TO COLD AND OF DIET ON COENZYME A LEVELS IN TISSUES

1960 ◽  
Vol 38 (1) ◽  
pp. 175-185
Author(s):  
James Campbell ◽  
Gordon R. Green ◽  
Eduard Schönbaum ◽  
Harvey Socol
Keyword(s):  
Ascorbic Acid ◽  
Adrenal Glands ◽  
Coenzyme A ◽  
Pantothenic Acid ◽  
Whole Body ◽  
Unit Weight ◽  
Adult Rats ◽  
Fresh Tissue ◽  
Exposure To Cold ◽  
Complete Diet

Exposure of adult rats to a cold environment increased the coenzyme A (CoA) extractable from their livers. The increases, in rats fed a complete diet, were found within 3 days, and were larger the longer the duration of exposure, amounting to 6, 27, and 60% above the control values after 3, 17, and 24 days respectively. The relations were similar when the CoA from the liver was expressed per unit weight of fresh tissue, or of liver total solids, or of whole body. When rats were fed a diet deficient in pantothenic acid, exposure to cold also resulted in elevation of CoA in the liver, but the differences did not progress with the duration of exposure. The liver CoA was further increased by the addition of large amounts of ascorbic acid to both the complete and the pantothenate-deficient diets. This effect of ascorbic acid occurred in rats under both ordinary and cold environmental conditions. Exposure to cold did not alter the concentration of CoA in the adrenal glands, but caused enlargement of the glands so that the amount of CoA in the adrenal per unit weight of the whole body increased. Other alterations in these animals exposed to cold included enlargement of the kidneys and heart, and decrease in depot fat. Deficiency of pantothenate in the diet slowed the rate of growth of young rats and significantly reduced the levels of CoA in the liver and the adrenal glands.

scholarly journals Whole-body Retention of 60Co Incorporated into a Seaweed in Rats

1979 ◽  
Vol 20 (1) ◽  
pp. 121-125
Author(s):  
J. INABA ◽  
Y. NISHIMURA ◽  
R. ICHIKAWA
Keyword(s):  
Whole Body ◽  
Body Retention
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