Production of extracellular bifidogenic growth stimulator (BGS) from Propionibacterium shermanii using a bioreactor system with a microfiltration module and an on-line controller for lactic acid concentration

2008 ◽  
Vol 105 (3) ◽  
pp. 184-191 ◽  
Author(s):  
Tomoaki Kouya ◽  
Kazuhiro Tobita ◽  
Masahito Horiuchi ◽  
Eri Nakayama ◽  
Hiroyoshi Deguchi ◽  
...  
1958 ◽  
Vol 192 (3) ◽  
pp. 577-580 ◽  
Author(s):  
Donald D. Van Fossan ◽  
Robert T. Clark

Simulated altitude exposure elevates the postmortem brain lactic acid concentration up to 98 mg/100 gm above controls depending on species used, duration, and intensity of exposure. The sharp difference in post-mortem brain lactic acid concentration between altitude exposed animals and controls remains demonstrable for the longest postmortem intervals studied (20 hr. in the dog, 30 hr. in the rabbit, and 6 hr. in the rat). Upon recovery from altitude exposure the brain lactic acid and/or precursors return toward pre-exposure levels in accordance with first order reaction kinetics during the first few minutes. The velocity constant is .32 and the half-life is 2.2 minutes. Elevated post-mortem brain lactic acid concentration is a constant finding in animals which were hypoxic at the time of death and appears to be a suitable criterion for establishing ante-mortem altitude exposure or other physiologically similar oxygen deficiency situations.


2016 ◽  
Vol 54 ◽  
pp. 202-213 ◽  
Author(s):  
Karen Gonzalez ◽  
Sihem Tebbani ◽  
Filipa Lopes ◽  
Aurore Thorigné ◽  
Sébastien Givry ◽  
...  

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