Elevated human epididymis protein 4 concentrations in chronic kidney disease

2012 ◽  
Vol 49 (4) ◽  
pp. 377-380 ◽  
Author(s):  
B. Nagy ◽  
Z. T. Krasznai ◽  
H. Balla ◽  
M. Csoban ◽  
P. Antal-Szalmas ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Human Epididymis Protein 4 ◽  
Human Epididymis

Cystatin C provides a better estimate of the effect of glomerular filtration rate on serum human epididymis protein 4 concentrations

2016 ◽  
Vol 54 (10) ◽  
Author(s):  
Simona Ferraro ◽  
Sara Pasqualetti ◽  
Assunta Carnevale ◽  
Mauro Panteghini
Keyword(s):  
Chronic Kidney Disease ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Cystatin C ◽  
Filtration Rate ◽  
Serum Concentrations ◽  
Glomerular Function ◽  
Human Epididymis Protein 4 ◽  
Disease Epidemiology ◽  
Human Epididymis

AbstractBackground:We evaluated the effect of kidney glomerular function on serum concentrations of human epididymis protein 4 (HE4) using creatinine (Cr), cystatin C (CysC) and related chronic kidney disease epidemiology collaboration (CKD-EPI) equations.Methods:We enrolled 101 women aged ≤56 years with a glomerular filtration rate (GFR) (estimated by CKD-EPI eGFRResults:A statistically significant increase in HE4 median concentrations was detected in subjects with an eGFRConclusions:Our study shows that a better estimate of the effect of GFR on serum HE4 is obtained by measuring CysC in serum or using CKD-EPI eGFR

Sign in / Sign up

Export Citation Format

Share Document