scholarly journals CCR5 Antagonists as Anti-HIV-1 Agents. 1. Synthesis and Biological Evaluation of 5-Oxopyrrolidine-3-carboxamide Derivatives

2004 ◽  
Vol 52 (1) ◽  
pp. 63-73 ◽  
Author(s):  
Shinichi Imamura ◽  
Yuji Ishihara ◽  
Taeko Hattori ◽  
Osamu Kurasawa ◽  
Yoshihiro Matsushita ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ccr5 Antagonists ◽  
Synthesis And Biological Evaluation ◽  
Anti Hiv ◽  
Hiv 1

CCR5 antagonists as anti-HIV-1 agents. Part 2: Synthesis and biological evaluation of N-[3-(4-benzylpiperidin-1-yl)propyl]-N,N′-diphenylureas

2004 ◽  
Vol 12 (9) ◽  
pp. 2295-2306 ◽  
Author(s):  
Shinichi Imamura ◽  
Osamu Kurasawa ◽  
Yoshi Nara ◽  
Takashi Ichikawa ◽  
Youichi Nishikawa ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ccr5 Antagonists ◽  
Synthesis And Biological Evaluation ◽  
Anti Hiv ◽  
Hiv 1

CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives

2005 ◽  
Vol 13 (2) ◽  
pp. 397-416 ◽  
Author(s):  
Shinichi Imamura ◽  
Youichi Nishikawa ◽  
Takashi Ichikawa ◽  
Taeko Hattori ◽  
Yoshihiro Matsushita ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ccr5 Antagonists ◽  
Synthesis And Biological Evaluation ◽  
Anti Hiv ◽  
Hiv 1

CCR5 Antagonists as anti-HIV-1 Agents. Part 1. Synthesis and Biological Evaluation of 5-Oxopyrrolidine-3-carboxamide Derivatives.

ChemInform ◽  
2004 ◽  
Vol 35 (31) ◽  
Author(s):  
Shinichi Imamura ◽  
Yuji Ishihara ◽  
Taeko Hattori ◽  
Osamu Kurasawa ◽  
Yoshihiro Matsushita ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Ccr5 Antagonists ◽  
Synthesis And Biological Evaluation ◽  
Anti Hiv ◽  
Hiv 1

Synthesis and Biological Evaluation of 8-Hydroxyquinoline-hydrazones for Anti-HIV-1 and Anticancer Potential

2018 ◽  
Vol 3 (38) ◽  
pp. 10727-10731 ◽  
Author(s):  
Purvi Shah ◽  
Leila F. Abadi ◽  
Shraddha Gaikwad ◽  
Dasharath Chaudhari ◽  
Varun Kushwah ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Synthesis And Biological Evaluation ◽  
Anti Hiv ◽  
Hiv 1

Design, synthesis, and biological evaluation of novel trifluoromethyl indoles as potent HIV-1 NNRTIs with an improved drug resistance profile

2014 ◽  
Vol 12 (21) ◽  
pp. 3446-3458 ◽  
Author(s):  
Hai-Xia Jiang ◽  
Dao-Min Zhuang ◽  
Ying Huang ◽  
Xing-Xin Cao ◽  
Jian-Hua Yao ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Resistance Profile ◽  
Drug Resistance Profile ◽  
Synthesis And Biological Evaluation ◽  
Anti Hiv ◽  
Hiv 1

A novel series of trifluoromethyl indoles have been designed, synthesized and evaluated for anti-HIV-1 activities.

Synthesis and biological evaluation of novel quinoxalinone-based HIV-1 reverse transcriptase inhibitors

MedChemComm ◽  
2014 ◽  
Vol 5 (4) ◽  
pp. 441-444 ◽  
Author(s):  
Jie Zhou ◽  
Mingyu Ba ◽  
Bo Wang ◽  
Haibo Zhou ◽  
Jianbo Bie ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Biological Evaluation ◽  
Reverse Transcriptase Inhibitors ◽  
Quinoxalinone Derivatives ◽  
Synthesis And Biological Evaluation ◽  
Anti Hiv ◽  
Hiv 1

A series of novel quinoxalinone derivatives were identified as potent anti-HIV-1 agents with IC50 values at 10−8 μmol L−1 level.

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