scholarly journals Anti-tumor Promoting Activities of Natural Products. II. Inhibitory Effects of Digitoxin on Two-Stage Carcinogenesis of Mouse Skin Tumors and Mouse Pulmonary Tumors.

1993 ◽  
Vol 16 (9) ◽  
pp. 930-931 ◽  
Author(s):  
Akira INADA ◽  
Tsutomu NAKANISHI ◽  
Takao KONOSHIMA ◽  
Mutsuo KOZUKA ◽  
Harukuni TOKUDA ◽  
...  
Keyword(s):  
Natural Products ◽  
Mouse Skin ◽  
Skin Tumors ◽  
Inhibitory Effects ◽  
Two Stage ◽  
Pulmonary Tumors

Inhibitory Effects of Lanostane-Type Triterpene Acids, the Components of Poria cocos, on Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate in Two-Stage Carcinogenesis in Mouse Skin

Oncology ◽  
1996 ◽  
Vol 53 (5) ◽  
pp. 382-385 ◽  
Author(s):  
Tomohiro Kaminaga ◽  
Ken Yasukawa ◽  
Hiroshi Kanno ◽  
Takaaki Tai ◽  
Yoshiki Nunoura ◽  
...  
Keyword(s):  
Mouse Skin ◽  
Tumor Promotion ◽  
Inhibitory Effects ◽  
Two Stage ◽  
Poria Cocos ◽  
Triterpene Acids

scholarly journals Inhibitory Effects of Cucurbitane Triterpenoids on Epstein-Barr Virus Activation and Two-Stage Carcinogenesis of Skin Tumors.

1994 ◽  
Vol 17 (5) ◽  
pp. 668-671 ◽  
Author(s):  
Takao KONOSHIMA ◽  
Midori TAKASAKI ◽  
Takeshi TATSUMOTO ◽  
Mutsuo KOZUKA ◽  
Ryoji KASAI ◽  
...  
Keyword(s):  
Epstein Barr Virus ◽  
Skin Tumors ◽  
Inhibitory Effects ◽  
Two Stage ◽  
Barr Virus ◽  
Epstein Barr

scholarly journals Inhibitory Effects of Gymnema (Gymnema sylvestre) Leaves on Tumour Promotion in Two-Stage Mouse Skin Carcinogenesis

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Ken Yasukawa ◽  
Sakiko Okuda ◽  
Yasuhito Nobushi
Keyword(s):  
Mouse Skin ◽  
Ethanol Extract ◽  
Skin Carcinogenesis ◽  
Gymnema Sylvestre ◽  
Active Fraction ◽  
Inhibitory Effects ◽  
Two Stage ◽  
Tumour Promotion ◽  
Ethanol Extracts

Ethanol extracts of gymnema (Gymnema sylvestre) leaves exhibited marked antitumour-promoting activity in anin vivotwo-stage carcinogenesis test in mice using 7,12-dimethylbenz[a]anthracene as an initiator and 12-O-tetradecanoylphorbol-13-acetate (TPA) as a promoter. From the active fraction of the ethanol extract of the gymnema leaves, three triterpenoids were isolated and identified. These compounds were evaluated for their inhibitory effects on TPA-induced inflammation (1 µg/ear) in mice. The tested compounds showed marked anti-inflammatory effects, with a 50% inhibitory dose of 50–555 nmol/ear.

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